Browsing Department of Chemistry by Title
Now showing items 111-130 of 280
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Gas Chromatography optimization using experimental design and surface response methodology.
(Master thesis, 2018-10-25)Gas Chromatography (GC) is an analytical method for the separation of enormous range of routine applications, to analyse very complex mixtures of Petroleum, such us different proteins in the human body, and natural products. ... -
GLORY: Generator of the structures of likely cytochrome P450 metabolites based on predicted sites of metabolism
(Peer reviewed; Journal article, 2019-06-12)Computational prediction of xenobiotic metabolism can provide valuable information to guide the development of drugs, cosmetics, agrochemicals, and other chemical entities. We have previously developed FAME 2, an effective ... -
Hit Dexter 2.0: Machine-Learning Models for the Prediction of Frequent Hitters
(Journal article; Peer reviewed, 2019)Assay interference caused by small molecules continues to pose a significant challenge for early drug discovery. A number of rule-based and similarity-based approaches have been derived that allow the flagging of potentially ... -
Ikkje god, ikkje dårleg, men berre OK. Det er bra. Ei kvalitativ studie om etterarbeid ved vurderingar i kjemifaget i vidaregåande skule
(Master thesis, 2011-05-30)This thesis is mainly based on my interviews of four chemistry teachers and nine chemistry pupils. The goal of the thesis is to find out how teachers and pupils continue working with a subject after the pupils has been ... -
Impact of fish protein concentrate on apparent viscosity and physical properties of soy protein concentrate subjected to thermomechanical treatment
(Peer reviewed; Journal article, 2019-04-30)The aim of this research was to investigate the plasticizing and binding effect of fish protein concentrate (FPC) on soy protein concentrate (SPC) with the use of a capillary rheometer with pre-shearing capabilities. A ... -
Important Differences and Potential Synergies between Traditional Chinese Medicine and Western Medicine, and the Isolation of Natural Products from Bretschneidera Sinensis
(Master thesis, 2010-05-19)Summary Traditional Chinese medicine (TCM) has been an important medical system in China for thousands of years. Lately, certain techniques like acupuncture and herbal medicines are also becoming increasingly popular in ... -
Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)
(Peer reviewed; Journal article, 2017-01)Here we report a series of close analogues of our recently published scaffold-based tripeptidomimetic CXCR4 antagonists, containing positively charged guanidino groups in R1 and R2, and an aromatic group in R3. While ... -
The influence of crude oil acids on natural inhibition of hydrate plugs
(Doctoral thesis, 2009-03-26)Gas hydrates can form in petroleum production systems of natural gas, water and crude oil. In some systems the hydrates agglomerate rapidly into large plugs that cause hazardous blockages of e.g. transport pipelines. The ... -
The influence of pipeline wettability and crude oil composition on deposition of gas hydrates during petroleum production
(Doctoral thesis, 2010-02-05)At specific temperature and pressure conditions, hydrates can sometimes plug production pipelines. It has been shown that some oils contain natural inhibiting compounds (NICs) that prevent hydrate plug formation even though ... -
Inklusjonskompleks mellom β-syklodekstrin og surfaktantene natrium dodekyl sulfat og natrium dekanoat
(Master thesis, 2002)Det er utført tetthets- og ultralydsmålinger på fortynningsserier av natrium dekanoat og natrium dodekyl sulfat i vann- og i β-syklodekstrin/vann- løsninger, med konsentrasjoner over og under kritisk micelle konsentrasjon, ... -
Intensive lifestyle intervention provides rapid reduction of serum fatty acid levels in women with severe obesity without lowering omega-3 to unhealthy levels
(Peer reviewed; Journal article, 2016-08)Serum fatty acid (FA) levels were monitored in women with severe obesity during intensive lifestyle intervention. At baseline, total FA levels and most individual FAs were elevated compared to a matching cohort of normal ... -
Interaksjon av Coenzym Q10 på lipidmonolag. Effekt av ulike konsentrasjoner Coenzym Q10 på lipidmonolag studert ved Langmuir monolagsteknikk.
(Master thesis, 2013-12-12)Biologiske membraner er bygd opp som et bilag bestående av lipider, proteiner og karbohydrater. Coenzym Q10 (CoQ10) utgjør den største fysiologiske formen av ubiquinoner hos dyr og mennesker. Denne forbindelsen har ... -
Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates
(Peer reviewed; Journal article, 2019)Membrane-binding interfaces of peripheral proteins are restricted to a small part of their exposed surface, so the ability to engage in strong selective interactions with membrane lipids at various depths in the interface, ... -
Interpretation of associations between the accelerometry physical activity spectrum and cardiometabolic health and locomotor skills in two cohorts of children using raw, log-transformed, or compositional data
(Journal article; Peer reviewed, 2020)It is discussed whether associations between accelerometer-derived physical activity intensities and outcomes should be analysed as absolute or relative data. The aim of the present study was to compare interpretation of ... -
Interpretation of chromatographic and mass spectrometric data from analyses of fatty acid methyl esters Application of multivariate methods
(Doctoral thesis, 2006-11-10)The purpose of this work has been to develop tools for fatty acid identification, with special emphasis on poly-unsaturated fatty acids and trans fatty acids. The work is based on application of gas chromatography with ... -
Interpretation of multivariate association patterns between multicollinear physical activity accelerometry data and cardiometabolic health in children-a tutorial
(Peer reviewed; Journal article, 2019-07-02)Associations between multicollinear accelerometry-derived physical activity (PA) data and cardiometabolic health in children needs to be analyzed using an approach that can handle collinearity among the explanatory variables. ... -
The intriguing Cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding
(Peer reviewed; Journal article, 2010-10-04)Background: Cyclophilin A (CypA) represents a potential target for antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication, although the mechanism through which ... -
Investigation of serum protein profiles in scrapie infected sheep by means of SELDI-TOF-MS and multivariate data analysis
(Peer reviewed; Journal article, 2013-11-14)Background: Classical scrapie in sheep is a fatal neurodegenerative disease associated with the conversion PrPC to PrPSc. Much is known about genetic susceptibility, uptake and dissemination of PrPSc in the body, but many ... -
An investigation of the correlation between interfacial properties and phase composition in the crude oil/water system
(Master thesis, 2015-12-01)Enhanced oil recovery can be obtained by flooding the reservoir with chemical fluids. However, complex interactions between the crude oil components, floodwater composition and reservoir rock minerology have to be comprehended ...