Blar i Department of Chemistry på forfatter "Clementsen, Maren Heskestad"
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Synthesis of substituted imidazoles that stabilizes Survival Motor Neuron Protein for treatment of Spinal Muscular Atrophy
Clementsen, Maren Heskestad (Master thesis, 2019-08-31)Spinal muscular atrophy (SMA) is a common autosomal recessive disorder and the leading cause of infant mortality. Patients with this disorder are missing the SMN1 gene that is producing 80-90 % of the Spinal motor neuron ...