Browsing Department of Chemistry by Author "Reuter, Nathalie"

Now showing items 1-5 of 5

    • Dissecting peripheral protein-membrane interfaces 

      Tubiana, Thibault Michel Joseph; Sillitoe, Ian; Orengo, Christine; Reuter, Nathalie (Journal article; Peer reviewed, 2022-12-14)
      Peripheral membrane proteins (PMPs) include a wide variety of proteins that have in common to bind transiently to the chemically complex interfacial region of membranes through their interfacial binding site (IBS). In ...

    • Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates 

      Waheed, Qaiser; Khan, Hanif Muhammad; He, Tao; Roberts, Mary F.; Gershenson, Anne; Reuter, Nathalie (Peer reviewed; Journal article, 2019)
      Membrane-binding interfaces of peripheral proteins are restricted to a small part of their exposed surface, so the ability to engage in strong selective interactions with membrane lipids at various depths in the interface, ...

    • Membrane models for molecular simulations of peripheral membrane proteins 

      Moqadam, Mahmoud; Tubiana, Thibault Michel Joseph; Moutoussamy, Emmanuel Edouard; Reuter, Nathalie (Journal article; Peer reviewed, 2021)
      Peripheral membrane proteins (PMPs) bind temporarily to the surface of biological membranes. They also exist in a soluble form and their tertiary structure is often known. Yet, their membrane-bound form and their ...

    • PDBe-KB: collaboratively defining the biological context of structural data 

      Varadi, Mihaly; Anyango, Stephen; Armstrong, David; Berrisford, John; Choudhary, Preeti; Deshpande, Mandar; Nadzirin, Nurul; Nair, Sreenath S.; Pravda, Lukas; Tanweer, Ahsan; Al-Lazikani, Bissan; Andreini, Claudia; Barton, Geoffrey J.; Bednar, David; Berka, Karel; Blundell, Tom; Brock, Kelly P.; Carazo, Jose Maria; Damborsky, Jiri; David, Alessia; Dey, Sucharita; Dunbrack, Roland; Recio, Juan Fernandez; Fraternali, Franca; Gibson, Toby; Helmer-Citterich, Manuela; Hoksza, David; Hopf, Thomas; Jakubec, David; Kannan, Natarajan; Krivak, Radoslav; Kumar, Manjeet; Levy, Emmanuel D.; London, Nir; Macias, Jose Ramon; Srivatsan, Madhusudhan M.; Marks, Debora S.; Martens, Lennart; McGowan, Stuart A.; McGreig, Jake E.; Modi, Vivek; Parra, R. Gonzalo; Pepe, Gerardo; Piovesan, Damiano; Prilusky, Jaime; Putignano, Valeria; Radusky, Leandro G.; Ramasamy, Pathmanaban; Rausch, Atilio O.; Reuter, Nathalie; Rodriguez, Luis A.; Rollins, Nathan J.; Rosato, Antonio; Rubach, Paweł; Serrano, Luis; Singh, Gulzar; Skoda, Petr; Sorzano, Carlos Oscar S.; Stourac, Jan; Sulkowska, Joanna I.; Svobodova, Radka; Tichshenko, Natalia; Tosatto, Silvio C.E.; Vranken, Wim; Wass, Mark N.; Xue, Dandan; Zaidman, Daniel; Thornton, Janet; Sternberg, Michael; Orengo, Christine; Velankar, Sameer (Journal article; Peer reviewed, 2022)
      The Protein Data Bank in Europe – Knowledge Base (PDBe-KB, https://pdbe-kb.org) is an open collaboration between world-leading specialist data resources contributing functional and biophysical annotations derived from or ...

    • Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3 

      Maximova, Ksenia; Reuter, Nathalie; Trylska, Joanna (Peer reviewed; Journal article, 2019)
      Proteinase 3 (PR3), together with other serine proteases, such as neutrophil elastase (NE) and cathepsin G (CG), regulates inflammatory and immune responses. However, in comparison with NE and CG, there is increasing ...