Blar i Department of Chemistry på tidsskrift "Frontiers in Chemistry"
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GLORY: Generator of the structures of likely cytochrome P450 metabolites based on predicted sites of metabolism
(Peer reviewed; Journal article, 2019-06-12)Computational prediction of xenobiotic metabolism can provide valuable information to guide the development of drugs, cosmetics, agrochemicals, and other chemical entities. We have previously developed FAME 2, an effective ... -
Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
(Journal article; Peer reviewed, 2023)Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N-terminal acetyltransferase NAA80 is ...