• GLORY: Generator of the structures of likely cytochrome P450 metabolites based on predicted sites of metabolism 

      de Bruyn Kops, Christina; Stork, Conrad; Sicho, Martin; Kochev, Nikolay; Svozil, Daniel; Jeliazkova, Nina; Kirchmair, Johannes (Peer reviewed; Journal article, 2019-06-12)
      Computational prediction of xenobiotic metabolism can provide valuable information to guide the development of drugs, cosmetics, agrochemicals, and other chemical entities. We have previously developed FAME 2, an effective ...
    • Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80 

      Myklebust, Line Merethe; Baumann, Markus; Støve, Svein Isungset; Foyn, Håvard; Arnesen, Thomas; Haug, Bengt Erik (Journal article; Peer reviewed, 2023)
      Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N-terminal acetyltransferase NAA80 is ...