Blar i Department of Mathematics på tidsskrift "PLoS Computational Biology"
Viser treff 1-5 av 5
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Determining individual variation in growth and its implication for life-history and population processes using the Empirical Bayes method
(Peer reviewed; Journal article, 2014-09-11)The differences in demographic and life-history processes between organisms living in the same population have important consequences for ecological and evolutionary dynamics. Modern statistical and computational methods ... -
Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations
(Peer reviewed; Journal article, 2019-06-26)The dynamics of the cellular proportion of mutant mtDNA molecules is crucial for mitochondrial diseases. Cellular populations of mitochondria are under homeostatic control, but the details of the control mechanisms involved ... -
Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions
(Journal article; Peer reviewed, 2023)Mitochondria are highly dynamic organelles, containing vital populations of mitochondrial DNA (mtDNA) distributed throughout the cell. Mitochondria form diverse physical structures in different cells, from cell-wide ... -
A new framework for assessing subject-specific whole brain circulation and perfusion using MRI-based measurements and a multi-scale continuous flow model
(Peer reviewed; Journal article, 2019-06-25)A large variety of severe medical conditions involve alterations in microvascular circulation. Hence, measurements or simulation of circulation and perfusion has considerable clinical value and can be used for diagnostics, ... -
Perfusion estimation using synthetic MRI-based measurements and a porous media flow model
(Journal article; Peer reviewed, 2023)The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis ...