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dc.contributor.authorChandyo, Ram Krishnaen_US
dc.contributor.authorHenjum, Sigrunen_US
dc.contributor.authorUlak, Manjesworien_US
dc.contributor.authorThorne-Lyman, Andrew Len_US
dc.contributor.authorUlvik, Rune Johanen_US
dc.contributor.authorShrestha, Prakash Sunderen_US
dc.contributor.authorLocks, Lindseyen_US
dc.contributor.authorFawzi, Wafaie W.en_US
dc.contributor.authorStrand, Tor A.en_US
dc.PublishedEuropean Journal of Clinical Nutrition 2015eng
dc.description.abstractBackground/Objectives: Iron deficiency anemia is a widespread public health problem, particularly in low- and middle-income countries. Maternal iron status around and during pregnancy may influence infant iron status. We examined multiple biomarkers to determine the prevalence of iron deficiency and anemia among breastfed infants and explored its relationship with maternal and infant characteristics in Bhaktapur, Nepal. Subjects/Methods: In a cross-sectional survey, we randomly selected 500 mother–infant pairs from Bhaktapur municipality. Blood was analyzed for hemoglobin, ferritin, total iron-binding capacity, transferrin receptors and C-reactive protein. Results: The altitude-adjusted prevalence of anemia was 49% among infants 2–6-month-old (hemaglobin (Hb) <10.8 g/dl) and 72% among infants 7–12-month-old (Hb <11.3 g/dl). Iron deficiency anemia, defined as anemia and serum ferritin <20 or <12 μg/l, affected 9 and 26% of infants of these same age groups. Twenty percent of mothers had anemia (Hb <12.3 g/dl), but only one-fifth was explained by depletion of iron stores. Significant predictors of infant iron status and anemia were infant age, sex and duration of exclusive breastfeeding and maternal ferritin concentrations. Conclusions: Our findings suggest that iron supplementation in pregnancy is likely to have resulted in a low prevalence of postpartum anemia. The higher prevalence of anemia and iron deficiency among breastfed infants compared with their mothers suggests calls for intervention targeting newborns and infants.en_US
dc.publisherNature Publishing Groupeng
dc.rightsAttribution CC BY-NC-NDeng
dc.titleThe prevalence of anemia and iron deficiency is more common in breastfed infants than their mothers in Bhaktapur, Nepalen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2015 The Authors

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