• 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
    • ADHD symptoms in neurometabolic diseases: Underlying mechanisms and clinical implications 

      Homaei, Selina Cannon; Barone, Helene; Kleppe, Rune; Betari, Nibal; Reif, Andreas; Haavik, Jan (Journal article; Peer reviewed, 2021)
      Neurometabolic diseases (NMDs) are typically caused by genetic abnormalities affecting enzyme functions, which in turn interfere with normal development and activity of the nervous system. Although the individual disorders ...
    • Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets 

      Postema, Merel C.; Hoogman, Martine; Ambrosino, Sara; Asherson, Philip; Banaschewski, Tobias; Bandeira, Cibele E.; Baranov, Alexandr; Bau, Claiton H.D.; Baumeister, Sarah; Baur-Streubel, Ramona; Bellgrove, Mark A.; Biederman, Joseph; Bralten, Janita; Brandeis, Daniel; Brem, Silvia; Buitelaar, Jan K.; Busatto, Geraldo F.; Castellanos, Francisco X.; Cercignani, Mara; Chaim-Avancini, Tiffany M.; Chantiluke, Kaylita C.; Christakou, Anastasia; Coghill, David; Conzelmann, Annette; Cubillo, Ana; Cupertino, Renata B.; de Zeeuw, Patrick; Doyle, Alysa E.; Durston, Sarah; Earl, Eric A.; Epstein, Jeffery N.; Ethofer, Thomas; Fair, Damien A.; Fallgatter, Andreas J.; Faraone, Stephen V.; Frodl, Thomas; Gabel, Matt C.; Gogberashvili, Tinatin; Grevet, Eugenio H.; Haavik, Jan; Harrison, Neil A.; Hartman, Catharina A.; Heslenfeld, Dirk J.; Hoekstra, Pieter J.; Hohmann, Sarah; Høvik, Marie Farstad; Jernigan, Terry L.; Kardatzki, Bernd; Karkashadze, George A.; Kelly, Clare; Kohls, Gregor; Konrad, Kerstin; Kuntsi, Jonna; Lazaro, Luisa; Lera-Miguel, Sara; Lesch, Klaus-Peter; Louza, Mario R.; Lundervold, Astri J.; Malpas, Charles B.; Mattos, Paulo; McCarthy, Hazel; Namazova-Baranova, Leyla; Nicolau, Rosa; Nigg, Joel T.; Novotny, Stephanie E.; Oberwelland Weiss, Eileen; O'Gorman Tuura, Ruth L.; Oosterlaan, Jaap; Oranje, Bob; Paloyelis, Yannis; Pauli, Paul; Picon, Felipe A.; Plessen, Kerstin J.; Ramos-Quiroga, J. Antoni; Reif, Andreas; Reneman, Liesbeth; Rosa, Pedro G.P.; Rubia, Katya; Schrantee, Anouk; Schweren, Lizanne J.S.; Seitz, Jochen; Shaw, Philip; Silk, Tim J.; Skokauskas, Norbert; Soliva, Joan Carles; Stevens, Michael C.; Sudre, Gustavo; Tamm, Leanne; Tovar-Moll, Fernanda; van Erp, Theo G.M.; Vance, Alasdair; Vilarroya, Oscar; Vives-Gilabert, Yolanda; von Polier, Georg G.; Walitza, Susanne; Yoncheva, Yuliya N.; Zanetti, Marcus V; Ziegler, Georg C.; Glahn, David C.; Jahanshad, Neda; Medland, Sarah E.; Thompson, Paul M.; Fisher, Simon E.; Franke, Barbara; Francks, Clyde (Journal article; Peer reviewed, 2021)
      Objective Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the ...
    • Anterior cingulate gamma-aminobutyric acid concentrations and electroconvulsive therapy 

      Erchinger, Vera Jane; Miller, Jeremy; Jones, Thomas; Kessler, Ute; Bustillo, Juan R.; Haavik, Jan; Petrillo, Jonathan; Ziomek, Gregory; Hammar, Åsa; Ødegaard, Ketil Joachim; Calhoun, Vince D.; McClintock, Shawn M.; Ersland, Lars; Oltedal, Leif; Abbott, Christopher (Journal article; Peer reviewed, 2020-09-17)
      Objective The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory ...
    • Association of sweetened carbonated beverage consumption during pregnancy and ADHD symptoms in the ofspring: a study from the Norwegian Mother, Father and Child Cohort Study (MoBa) 

      Kvalvik, Liv Grimstvedt; Klungsøyr, Kari; Igland, Jannicke; Caspersen, Ida Henriette; Brantsæter, Anne Lise; Solberg, Berit Skretting; Hartman, Catharina; Schweren, Lizanne Johanna Stephanie; Larsson, Henrik; Li, Lin; Forthun, Ingeborg; Johansson, Stefan; Vasquez, Alejandro Arias; Haavik, Jan (Journal article; Peer reviewed, 2022)
      Purpose Intrauterine exposures influence offspring health and development. Here we investigated maternal intake of sweetened carbonated beverages (SCB) during pregnancy and its association with ADHD symptoms in the ...
    • Attention-deficit/hyperactivity disorder and smoking habits in pregnant women 

      Anderson, Anneli; Hegvik, Tor-Arne; Chen, Qi; Kvalvik, Liv Grimstvedt; Almqvist, Catarina; D'Onofrio, Brian M.; Hartman, Catharina A; Klungsøyr, Kari; Haavik, Jan; Tuvblad, Catherine; Larsson, Henrik (Journal article; Peer reviewed, 2020)
      Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with an increased risk of tobacco smoking, and more difficulties with smoking cessation compared to non-ADHD individuals. Women with ADHD may ...
    • Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure 

      Hoogman, Martine; Van Rooij, Daan; Klein, Marieke; Boedhoe, Premika; Ilioska, Iva; Li, Ting; Patel, Yash; Postema, Merel C.; Zhang-James, Yanli; Anagnostou, Evdokia; Arango, Celso; Auzias, Guillaume; Banaschewski, Tobias; Bau, Claiton H.D.; Behrmann, Marlene; Bellgrove, Mark A.; Brandeis, Daniel; Brem, Silvia; Busatto, Geraldo F.; Calderoni, Sara; Calvo, Rosa; Castellanos, Francisco X.; Coghill, David; Conzelmann, Annette; Daly, Eileen; Deruelle, Christine; Dinstein, Ilan; Durston, Sarah; Ecker, Christine; Ehrlich, Stefan; Epstein, Jeffery N.; Fair, Damien A.; Fitzgerald, Jacqueline; Freitag, Christine; Frodl, Thomas; Gallagher, Louise; Grevet, Eugenio H.; Haavik, Jan; Hoekstra, Pieter J.; Janssen, Joost; Karkashadze, George A.; King, Joseph A.; Konrad, Kerstin; Kuntsi, Jonna; Lazaro, Luisa; Lerch, Jason P.; Lesch, Klaus-Peter; Louza, Mario R.; Luna, Beatriz; Mattos, Paulo; McGrath, Jane; Muratori, Filippo; Murphy, Clodagh; Nigg, Joel T.; Oberwelland Weiss, Eileen; O'Gorman Tuura, Ruth L.; O'Hearn, Kirsten; Oosterlaan, Jaap; Parellada, Mara; Pauli, Paul; Plessen, Kerstin von; Ramos-Quiroga, Josep Antoni; Reif, Andreas; Reneman, Liesbeth; Retico, Alessandra; Rosa, Pedro G.; Rubia, Katya; Shaw, Philip; Silk, Tim J.; Tamm, Leanne; Vilarroya, Oscar; Walitza, Susanne; Jahanshad, Neda; Faraone, Stephen V.; Francks, Clyde; van den Heuvel, Odile A.; Paus, Tomáš; Thompson, Paul M.; Buitelaar, Jan; Franke, Barbara (Journal article; Peer reviewed, 2020)
      Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main ...
    • Current and Retrospective Childhood Ratings of Emotional Fluctuations in Adults With ADHD 

      Lundervold, Astri J.; Halmøy, Anne; Nordby, Emilie Sektnan; Haavik, Jan; Meza, Jocelyn I. (Journal article; Peer reviewed, 2020)
      Introduction: Emotional fluctuations and mood swings are common among adults with Attention Deficit/Hyperactivity Disorder (ADHD). Here we investigated if these problems could be retrospectively traced back to childhood ...
    • Diet quality, stress and common mental health problems: A cohort study of 121,008 adults 

      Schweren, Lizanne J.S.; Larsson, Henrik; Vinke, Petra C.; Li, Lin; Kvalvik, Liv Grimstvedt; Arias-Vasquez, Alejandro; Haavik, Jan; Hartman, Catharina A. (Journal article; Peer reviewed, 2021)
      Background & aims Overall diet quality may partially mediate the detrimental effects of stress and neuroticism on common mental health problems: stressed and/or neurotic individuals may be more prone to unhealthy dietary ...
    • Diet, Physical Activity, and Disinhibition in Middle-Aged and Older Adults: A UK Biobank Study 

      Schweren, Lizanne J.S.; van Rooij, Daan; Shi, Huiqing; Larsson, Henrik; Arias-Vasquez, Alejandro; Li, Lin; Kvalvik, Liv Grimstvedt; Haavik, Jan; Buitelaar, Jan; Hartman, Catharina (Journal article; Peer reviewed, 2021)
      Disinhibition is a prominent feature of multiple psychiatric disorders, and has been associated with poor long-term somatic outcomes. Modifiable lifestyle factors including diet and moderate-to-vigorous physical activity ...
    • Discovery and biological characterization of a novel scaffold for potent inhibitors of peripheral serotonin synthesis 

      Betari, Nibal; Sahlholm, Kristoffer; Ishizuka, Yuta; Teigen, Knut; Haavik, Jan (Journal article; Peer reviewed, 2020)
      Aim: Tryptophan hydroxylase 1 (TPH1) catalyzes serotonin synthesis in peripheral tissues. Selective TPH1 inhibitors may be useful for treating disorders related to serotonin dysregulation. Results & methodology: Screening ...
    • Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs 

      Sønderby, Ida Elken; Ching, Christopher R. K.; Thomopoulos, Sophia I.; van der Meer, Dennis; Sun, Daqiang; Villalon-Reina, Julio E.; Agartz, Ingrid; Amunts, Katrin; Arango, Celso; Armstrong, Nicola J.; Ayesa-Arriola, Rosa; Bakker, Geor; Bassett, Anne S.; Boomsma, Dorret I.; Bulow, Robin; Butcher, Nancy J.; Calhoun, Vince D.; Caspers, Svenja; Chow, Eva W. C.; Cichon, Sven; Ciufolini, Simone; Craig, Michael C.; Crespo-Facorro, Benedicto; Cunningham, Adam C.; Dale, Anders M.; Dazzan, Paola; de Zubicaray, Greig I.; Djurovic, Srdjan; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Durdle, Courtney A.; Ehrlich, Stefan; Emanuel, Beverly S.; Espeseth, Thomas; Fisher, Simon E.; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Gur, Raquel E.; Gutman, Boris A.; Lundervold, Astri J.; Haavik, Jan; Håberg, Asta; Hansen, Laura A.; Moberget, Torgeir; Sánchez, Jennifer Monereo; Reinbold, Céline Sonja; Tamnes, Christian Krog; Westlye, Lars Tjelta; Andreassen, Ole; et al., , (Journal article; Peer reviewed, 2022)
      The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors ...
    • Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy 

      Opel, Nils; Narr, Katherine L; Abbott, Christopher; Argyelan, Miklos; Espinoza, Randall; Emsell, Louise; Bouckaert, Filip; Sienaert, Pascal; Vandenbulcke, Mathieu; Nordanskog, Pia; Repple, Jonathan; Kavakbasi, Erhan; Jorgensen, Martin B.; Paulson, Olaf B.; Hanson, Lars G.; Dols, Annemieke; van Exel, Eric; Oudega, Mardien L.; Takamiya, Akihiro; Kishimoto, Taishiro; Ousdal, Olga Therese; Haavik, Jan; Hammar, Åsa Karin; Ødegaard, Ketil Joachim; Kessler, Ute; Bartsch, Hauke; Dale, Anders M.; Baune, Bernhard T; Dannlowski, Udo; Oltedal, Leif; Redlich, Ronny (Journal article; Peer reviewed, 2021)
      Background: Obesity is a frequent somatic comorbidity of major depression, and it has been associated with worse clinical outcomes and brain structural abnormalities. Converging evidence suggests that electroconvulsive ...
    • Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis 

      Zhang-James, Yanli; Helminen, Emily C.; Liu, Jinru; Busatto, Geraldo F.; Calvo, Anna; Cercignani, Mara; Chaim-Avancini, Tiffany M.; Gabel, Matt C.; Harrison, Neil A.; Lazaro, Luisa; Lera-Miguel, Sara; Louza, Mario R.; Nicolau, Rosa; Rosa, Pedro G.; Schulte-Rutte, Martin; Zanetti, Marcus V.; Ambrosino, Sara; Asherson, Philip; Banaschewski, Tobias; Baranov, Alexandr; Baumeister, Sarah; Baur-Streubel, Ramona; Bellgrove, Mark A.; Biederman, Joseph; Bralten, Janita; Bramati, Ivanei; Brandeis, Daniel; Brem, Silvia; Buitelaar, Jan K.; Castellanos, Francisco X.; Chantiluke, Kaylita C.; Christakou, Anastasia; Coghill, David; Conzelmann, Annette; Cubillo, Ana; Dale, Anders M.; de Zeeuw, Patrick; Doyle, Alysa E.; Durston, Sarah; Earl, Eric A.; Epstein, Jeffery N.; Ethofer, Thomas; Fair, Damien A.; Fallgatter, Andreas J.; Frodl, Thomas; Gogberashvili, Tinatin; Haavik, Jan; Hartman, Catharina A.; Heslenfeld, Dirk J.; Hoekstra, Pieter J.; Hohmann, Sarah; Høvik, Marie Farstad; Jahanshad, Neda; Jernigan, Terry L.; Kardatzki, Bernd; Karkashadze, George A.; Kelly, Clare; Kohls, Gregor; Konrad, Kerstin; Kuntsi, Jonna; Lesch, Klaus-Peter; Lundervold, Astri J.; Malpas, Charles B.; Mattos, Paulo; McCarthy, Hazel; Mehta, Mitul A.; Namazova-Baranova, Leyla; Nigg, Joel T.; Novotny, Stephanie E.; O’Gorman Tuura, Ruth L.; Weiss, Eileen Oberwelland; Oosterlaan, Jaap; Oranje, Bob; Paloyelis, Yannis; Pauli, Paul; Plessen, Kerstin J.; Ramos-Quiroga, Josep Antoni; Reif, Andreas; Reneman, Liesbeth; Rubia, Katya; Schrantee, Anouk; Schwarz, Lena; Schweren, Lizanne J.S.; Seitz, Jochen; Shaw, Philip; Silk, Tim J.; Skokauskas, Norbert; Vila, Juan Carlos Soliva; Stevens, Michael C.; Sudre, Gustavo; Tamm, Leanne; Thompson, Paul M.; Tovar-Moll, Fernanda; van Erp, Theo G.M.; Vance, Alasdair; Vilarroya, Oscar; Vives-Gilabert, Yolanda; von Polier, Georg G.; Walitza, Susanne; Yoncheva, Yuliya N.; Ziegler, Georg C.; Franke, Barbara; Hoogman, Martine; Faraone, Stephen (Journal article; Peer reviewed, 2021)
      Attention-deficit/hyperactivity disorder (ADHD) affects 5% of children world-wide. Of these, two-thirds continue to have impairing symptoms of ADHD into adulthood. Although a large literature implicates structural brain ...
    • An Exploratory Investigation of Goal Management Training in Adults With ADHD: Improvements in Inhibition and Everyday Functioning 

      Jensen, Daniel André; Halmøy, Anne; Stubberud, Jan Egil; Haavik, Jan; Lundervold, Astri J.; Sørensen, Lin (Journal article; Peer reviewed, 2021)
      Background: Adults with attention deficit/hyperactivity disorder (ADHD) are predominantly treated with medication. However, there is also a need for effective, psychologically based interventions. As ADHD is strongly ...
    • Familial co-aggregation of attention-deficit/ hyperactivity disorder and autoimmune diseases: a cohort study based on Swedish population-wide registers 

      Hegvik, Tor-Arne; Chen, Qi; Kuja-Halkola, Ralf; Klungsøyr, Kari; Butwicka, Agnieszka; Lichtenstein, Paul; Almqvist, Catarina; Faraone, Stephen V.; Haavik, Jan; Larsson, Henrik (Journal article; Peer reviewed, 2021)
      Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with several autoimmune diseases (AD), both within individuals and across relatives, implying common underlying genetic or environmental factors ...
    • GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production 

      Mahootchi, Elaheh; Homaei, Selina Cannon; Kleppe, Rune; Winge, Ingeborg; Hegvik, Tor-Arne; Perez, Roberto Megias; Totland, Christian; Mogavero, Floriana; Baumann, Anne; Glennon, Jeffrey Colm; Miletic, Hrvoje; Kursula, Petri; Haavik, Jan (Journal article; Peer reviewed, 2020)
      Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This ...
    • Gene-Environment Interactions in Attention-Deficit/Hyperactivity Disorder Symptom Dimensions: The Role of Unhealthy Food Habits 

      Li, Lin; Taylor, Mark J; Bälter, Katarina; xie, tian; Solberg, Berit Skretting; Haavik, Jan; Arias-Vásquez, Alejandro; Hartman, Catharina A; Larsson, Henrik (Journal article; Peer reviewed, 2021)
      Background: Dietary habits were investigated as environmental risk factors for Attention-Deficit/Hyperactivity Disorder (ADHD). However, no previous studies explored the effects of dietary factors on modifying the role of ...
    • Genetic association study of childhood aggression across raters, instruments, and age 

      Ip, Hill F.; van der Laan, Camiel M.; Krapohl, Eva M. L.; Brikell, Isabell; Sánchez-Mora, Cristina; Nolte, Ilja M.; Pourcain, Beate St; Bolhuis, Koen; Palviainen, Teemu; Zafarmand, Hadi; Colodro-Conde, Lucía; Gordon, Scott; Zayats, Tetyana; Aliev, Fazil; Jiang, Chang; Wang, Carol A.; Saunders, Gretchen; Karhunen, Ville; Hammerschlag, Anke R.; Adkins, Daniel E.; Border, Richard; Peterson, Roseann E.; Prinz, Joseph A.; Thiering, Elisabeth; Seppälä, Iikka; Vilor-Tejedor, Natàlia; Ahluwalia, Tarunveer S.; Day, Felix R.; Hottenga, Jouke-Jan; Allegrini, Andrea G.; Rimfeld, Kaili; Chen, Qi; Yi, Lu; Martin, Joanna; Soler Artigas, Marìa; Rovira, Paula; Bosch, Rosa; Español, Gemma; Ramos-Quiroga, Josep Antonio; Neumann, Alexander; Haavik, Jan; Harris, Jennifer Ruth; Helgeland, Øyvind; Johansson, Stefan; Knudsen, Gun Peggy Strømstad; Njølstad, Pål Rasmus; Havdahl, Alexandra; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Boomsma, Dorret I. (Journal article; Peer reviewed, 2021)
      Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from ...
    • Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations 

      Betari, Nibal; Sahlholm, Kristoffer; Morató, Xavier; Godoy-Marín, Héctor; Jáuregui, Olga; Teigen, Knut; Ciruela, Francisco; Haavik, Jan (Journal article; Peer reviewed, 2020)
      Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including cardiovascular function, bowel motility, and platelet aggregation. 5-HT ...