• Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy 

      Wade, Benjamin; Hellemann, Gerhard S.; Espinoza, Randall; Woods, Roger P.; Joshi, Shantanu H.; Redlich, Ronny; Dannlowski, Udo; Jorgensen, Anders; Abbott, Christopher; Oltedal, Leif; Narr, Katherine L. (Journal article; Peer reviewed, 2021)
      Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We ...
    • Development and validation of a multimodal neuroimaging biomarker for electroconvulsive therapy outcome in depression: A multicenter machine learning analysis 

      Bruin, Willem Benjamin; Oltedal, Leif; Bartsch, Hauke; Abbott, Christopher; Argyelan, Miklos; Barbour, Tracy; Camprodon, Joan; Chowdhury, Samadrita; Espinoza, Randall; Mulders, Peter; Narr, Katherine; Oudega, Mardien; Rhebergen, Didi; Ten Doesschate, Freek; Tendolkar, Indira; Van Eijndhoven, Philip; Van Exel, Eric; Van Verseveld, Mike; Wade, Benjamin; Van Waarde, Jeroen; Zhutovsky, Paul; Dols, Annemiek; Van Wingen, Guido (Journal article; Peer reviewed, 2023)
      Background Electroconvulsive therapy (ECT) is the most effective intervention for patients with treatment resistant depression. A clinical decision support tool could guide patient selection to improve the overall ...