• Accurate population-based model for individual prediction of colon cancer recurrence 

      Österman, Erik; Ekström, Joakim; Sjöblom, Tobias; Kørner, Hartwig; Myklebust, Tor Åge; Guren, Marianne; Glimelius, Bengt (Journal article; Peer reviewed, 2021)
      Background Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models ...
    • Improving knowledge-based treatment planning for lung cancer radiotherapy with automatic multi-criteria optimized training plans 

      Fjellanger, Kristine; Hordnes, Marte; Sandvik, Inger Marie; Sulen, Turid Husevåg; Heijmen, Ben J. M.; Breedveld, Sebastiaan; Rossi, Linda; Pettersen, Helge Egil Seime; Hysing, Liv Bolstad (Journal article; Peer reviewed, 2023)
      Background: Knowledge-based planning (KBP) is a method for automated radiotherapy treatment planning where appropriate optimization objectives for new patients are predicted based on a library of training plans. KBP can ...
    • Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis 

      Nunes, Luís; Aasebø, Kristine; Mathot, Lucy; Ljungström, Viktor; Edqvist, Per-Henrik; Sundström, Magnus; Dragomir, Anca; Pfeiffer, Per; Ameur, Adam; Pontén, Fredrik; Mezheyeuski, Artur; Sorbye, Halfdan; Sjöblom, Tobias; Glimelius, Bengt (Journal article; Peer reviewed, 2020-01-10)
      Background: We have reported that BRAF V600E mutations and microsatellite instability-high (MSI-H) are more prevalent in a population-based cohort of metastatic colorectal cancer (mCRC) patients than has been reported from ...
    • Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms 

      Janson, Eva Tiensuu; Knigge, Ulrich; Dam, Gitte; Federspiel, Birgitte; Grønbaek, Henning; Stålberg, Peter; Langer, Seppo W.; Kjaer, Andreas; Arola, Johanna; Schalin-Jäntti, Camilla; Sundin, Anders; Welin, Staffan; Thiis-Evensen, Espen; Sorbye, Halfdan (Journal article; Peer reviewed, 2021)
      Background The diagnostic work-up and treatment of patients with gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) has undergone major advances and new methods are introduced. Furthermore, an update of the WHO ...
    • The power of empirical data; lessons from the clinical registry initiatives in Scandinavian cancer care 

      Nilbert, Mef; Thomsen, Linda Aagaard; Winther Jensen, Jens; Møller, Henrik; Borre, Michael; Widenlou Nordmark, Arvid; Lambe, Mats; Brändström, Helena; Kørner, Hartwig; Møller, Bjørn; Ursin, Giske (Journal article; Peer reviewed, 2020)
      Background In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment ...
    • Reduction of PTV margins for elective pelvic lymph nodes in online adaptive radiotherapy of prostate cancer patients 

      Brennsæter, John Alfred; Dahle, Tordis Johnsen; Moi, Jannicke Nøkling; Svanberg, Ingvild Førsvoll; Haaland, Gry Sandvik; Pilskog, Sara Margareta Cecilia (Journal article; Peer reviewed, 2023)
      Background Cone beam CT (CBCT) based online adaptive radiotherapy (oART) is a new development in radiotherapy. With oART, the requirements for planning target volume (PTV) margins differ from standard therapy because ...
    • Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors 

      Otterlei, Ole Marius; Indelicato, Daniel J.; Toussaint, Laura; Ytre-Hauge, Kristian; Pilskog, Sara; Fjæra, Lars Fredrik; Rørvik, Eivind; Pettersen, Helge Egil Seime; Muren, Ludvig Paul; Lassen-Ramshad, Yasmin; Di Pinto, Marcos; Stokkevåg, Camilla Hanquist (Journal article; Peer reviewed, 2021)
      Background Clinically, a constant value of 1.1 is used for the relative biological effectiveness (RBE) of protons, whereas in vitro the RBE has been shown to vary depending on physical dose, tissue type, and linear energy ...