Browsing University of Bergen Library by Journals "Biological Psychiatry"

Now showing items 1-11 of 11

    • Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology 

      van der Meer, Dennis; Shadrin, Alexey; O'Connell, Kevin Sean; Bettella, Francesco; Djurovic, Srdjan; Wolfers, Thomas; Alnæs, Dag; Agartz, Ingrid; Smeland, Olav Bjerkehagen; Melle, Ingrid; Sánchez, Jennifer Monereo; Linden, David E.J.; Dale, Anders; Westlye, Lars Tjelta; Andreassen, Ole; Frei, Oleksandr; Kaufmann, Tobias (Journal article; Peer reviewed, 2022)
      Background Schizophrenia is a complex polygenic disorder with subtle, distributed abnormalities in brain morphology. There are indications of shared genetic architecture between schizophrenia and brain measures despite ...

    • Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes 

      O'Connell, Kevin Sean; Frei, Oleksandr; Bahrami, Shahram; Smeland, Olav Bjerkehagen; Bettella, Francesco; Cheng, Weiqiu; Chu, Yunhan; Hindley, Guy; Lin, Aihua; Shadrin, Alexey; Barrett, Elizabeth Ann; Lagerberg, Trine Vik; Steen, Nils Eiel; Dale, Anders M.; Djurovic, Srdjan; Andreassen, Ole A. (Journal article; Peer reviewed, 2021)
      Background: A range of sleep disturbances are commonly experienced by patients with psychiatric disorders, and genome-wide genetic analyses have shown some significant genetic correlations between these traits. Here, we ...

    • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors 

      Mullins, Niamh; Kang, JooEun; Campos, Adrian I.; Coleman, Jonathan R.I.; Edwards, Alexis C.; Galfalvy, Hanga; Levey, Daniel F.; Lori, Adriana; Shabalin, Andrey A; Andreassen, Ole; Melle, Ingrid; Morken, Gunnar; Starnawska, Anna; Su, Mei-Hsin; Watson, Hunna J; Adams, Mark; Awasthi, Swapnil; Gandal, Michael; Hafferty, Jonathan; Hishimoto, Akitoyo; Kim, Minsoo; Okazaki, Satoshi; Otsuka, Ikuo; Ware, Erin B.; Stephan, Ripke; Bergen, Andrew W.; Berrettini, Wade H.; Bohus, Martin; Brandt, Harry; Chang, Xiao; Chen, Wei J; Chen, Hsi-Chung; Crawford, Steven; Crow, Scott; DiBlasi, Emily; Duriez, Philibert; Fichter, Manfred M; Fernández-Aranda, Fernando; Gallinger, Steven; Glatt, Stephen J.; Gorwood, Philip; Guo, Yiran; Hakonarson, Hakon; Halmi, Katherine A; Hwu, Hai-Gwo; Jain, Sonia; Jamain, Stephane; Jimenez-Murcia, Susana; Johnson, Craig; Djurovic, Srdjan (Journal article; Peer reviewed, 2022)
      Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ...

    • Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts 

      Parker, Nadine; Cheng, Weiqiu; Hindley, Guy; O'Connell, Kevin Sean; Karthikeyan, Sandeep; Holen, Børge; Shadrin, Alexey; Rahman, Zillur; Karadag, Naz; Bahrami, Shahram; Lin, Aihua; Steen, Nils Eiel; Ueland, Thor; Aukrust, Pål; Djurovic, Srdjan; Dale, Anders; Smeland, Olav Bjerkehagen; Frei, Oleksandr; Andreassen, Ole (Journal article; Peer reviewed, 2024)
      Background For many brain disorders, a subset of patients jointly exhibit alterations in cortical brain structure and elevated levels of circulating immune markers. This may be driven in part by shared genetic architecture. ...

    • Genome-wide analyses of vocabulary size in infancy and toddlerhood: associations with ADHD, literacy and cognition-related traits 

      Verhoef, Ellen; Allegrini, Andrea G.; Jansen, Philip R.; Lange, Katherine; Wang, Carol A.; Morgan, Angela; Ahluwalia, Tarunveer S.; Symeonides, Christos; Eising, Else; Franken, Marie-Christine; Hypponen, Elina; Mansell, Toby; Olislagers, Mitchell; Omerovic, Emina; Rimfeld, Kaili; Schlag, Fenja; Selzam, Saskia; Shapland, Chin Yang; Tiemeier, Henning; Whitehouse, Andrew J.O.; Saffery, Richard; Bønnelykke, Klaus; Reilly, Sheena; Pennell, Craig E.; Wake, Melissa; Cecil, Charlotte A. M.; Plomin, Robert; Fisher, Simon E.; St Pourcain, Beate; Andreassen, Ole; Bartels, Meike; Boomsma, Dorret; Dale, Philip S.; Ehli, Erik; Fernandez-Orth, Dietmar; Guxens, Mònica; Hakulinen, Christian; Harris, Kathleen Mullan; Haworth, Simon; de Hoyos, Lucía; Jaddoe, Vincent; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho; Middeldorp, Christel; Min, Josine L.; Mishra, Pashupati P.; Njølstad, Pål Rasmus; Sunyer, Jordi; Tate, Ashley E.; Timpson, Nicholas; van der Laan, Camiel; Vrijheid, Martine; Vuoksimaa, Eero; Whipp, Alyce M.; Ystrøm, Eivind (Journal article; Peer reviewed, 2024)
      Background The number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta–genome-wide ...

    • Genome-wide Association Analysis of Parkinson’s Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci 

      Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Bahrami, Shahram; Broce, Iris J.; Tesli, Martin Steen; Frei, Oleksandr; Wirgenes, Katrine Verena; O`Connell, Kevin; Krull, Florian; Bettella, Francesco; Steen, Nils Eiel; Sugrue, Leo P.; Wang, Yunpeng; Svenningsson, Per; Sharma, Manu; Pihlstrøm, Lasse; Toft, H. Mathias S.; O’Donovan, Michael; Djurovic, Srdjan; Desikan, Rahul S; Dale, Anders M.; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2021)
      Background Parkinson’s disease (PD) and schizophrenia (SCZ) are heritable brain disorders that involve dysregulation of the dopaminergic system. Epidemiological studies have reported potential comorbidity between the ...

    • Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum 

      Yang, Zhiyu; Wu, Hanrui; Lee, Phil H.; Tsetsos, Fotis; Davis, Lea K.; Yu, Dongmei; Lee, Sang Hong; Dalsgaard, Søren; Haavik, Jan; Barta, Csaba; Zayats, Tetyana; Eapen, Valsamma; Wray, Naomi R.; Devlin, Bernie; Daly, Mark; Neale, Benjamin; Børglum, Anders D.; Crowley, James J.; Scharf, Jeremiah; Mathews, Carol A.; Faraone, Stephen V.; Franke, Barbara; Mattheisen, Manuel; Smoller, Jordan W.; Paschou, Peristera (Journal article; Peer reviewed, 2021)
      Background Tourette syndrome (TS) is often found comorbid with other neurodevelopmental disorders across the impulsivity-compulsivity spectrum, with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder ...

    • Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia 

      Akkouh, Ibrahim Ahmed; Ueland, Thor; Szabo, Attila; Hughes, Timothy; Smeland, Olav Bjerkehagen; Andreassen, Ole; Requena Osete, Jordi; Djurovic, Srdjan (Journal article; Peer reviewed, 2024)
      Background Schizophrenia (SCZ) has a known neurodevelopmental etiology, but limited access to human prenatal brain tissue hampers the investigation of basic disease mechanisms in early brain development. Here, we elucidate ...

    • Maternal Fiber Intake During Pregnancy and Development of Attention-Deficit/Hyperactivity Disorder Symptoms Across Childhood: The Norwegian Mother, Father, and Child Cohort Study 

      Solberg, Berit Skretting; Kvalvik, Liv Grimstvedt; Instanes, Johanne Telnes; Hartman, Catharina A.; Klungsøyr, Kari; Li, Lin; Larsson, Henrik; Magnus, Per Minor; Njølstad, Pål Rasmus; Johansson, Stefan; Andreassen, Ole; Bakken, Nora Refsum; Bekkhus, Mona; Austerberry, Chloe; Smajlagic, Dinka; Havdahl, Alexandra; Corfield, Elizabeth Claire; Haavik, Jan; Gjestad, Rolf; Zayats, Tetyana (Journal article; Peer reviewed, 2023)
      Background Epidemiological studies suggest that maternal diet quality during pregnancy may influence the risk of neurodevelopmental disorders in offspring. Here, we investigated associations between maternal intake of ...

    • The Neurobiological Effects of Electroconvulsive Therapy Studied Through Magnetic Resonance: What Have We Learned, and Where Do We Go? 

      Ousdal, Olga Therese; Brancati, Giulio E.; Kessler, Ute; Erchinger, Vera; Dale, Anders M.; Abbott, Christopher; Oltedal, Leif (Journal article; Peer reviewed, 2021)
      Electroconvulsive therapy (ECT) is an established treatment choice for severe, treatment-resistant depression, yet its mechanisms of action remain elusive. Magnetic resonance imaging (MRI) of the human brain before and ...

    • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 

      Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Journal article; Peer reviewed, 2022)
      Background: Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...