Browsing University of Bergen Library by Journals "FEBS Letters"
Now showing items 1-3 of 3
-
K+ regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages
(Journal article; Peer reviewed, 2021)Pellino proteins are E3 ubiquitin ligases involved in the innate immune system. Recently, Pellino-2 was reported to modulate the activation of the mouse Nlrp3 inflammasome. We examined the intracellular localization of ... -
A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia
(Journal article; Peer reviewed, 2023)Ocular pterygium–digital keloid dysplasia (OPDKD) is a rare hereditary disease characterized by corneal ingrowth of vascularized conjunctival tissue early in life. Later, patients develop keloids on fingers and toes but ... -
Systemic interferon type I and B cell responses are impaired in autoimmune polyendocrine syndrome type 1
(Journal article; Peer reviewed, 2023)Autoimmune polyendocrine syndrome type I (APS-1) is caused by mutations in the autoimmune regulator (AIRE) gene and characterised clinically by multiple autoimmune manifestations and serologically by autoantibodies against ...