• A 38,000-year-old carving from Grotte des Gorges, Amange, Jura, France 

      d'Errico, Francesco; David, Serge; Coqueugniot, Hélène; Meister, Christian; Dutkiewicz, Ewa; Pigeaud, Romain; Sitzia, Luca; Cailhol, Didier; Bosq, Mathieu; Griggo, Christophe; Affolter, Jehanne; Queffelec, Alain; Doyon, Luc (Journal article; Peer reviewed, 2023)
      The earliest European carvings, made of mammoth ivory, depict animals, humans, and anthropomorphs. They are found at Early Aurignacian sites of the Swabian Jura in Germany. Despite the wide geographical spread of the ...
    • Accuracy and efficiency of germline variant calling pipelines for human genome data 

      Zhao, Sen; Agafonov, Oleg; Azab, Abdulrahman; Stokowy, Tomasz; Hovig, Eivind (Journal article; Peer reviewed, 2020)
      Advances in next-generation sequencing technology have enabled whole genome sequencing (WGS) to be widely used for identification of causal variants in a spectrum of genetic-related disorders, and provided new insight into ...
    • Accuracy of single intravenous access iohexol GFR in children is hampered by marker contamination 

      Eide, Thea Tislevoll; Hufthammer, Karl Ove; Brun, Atle; Brackman, Damien; Svarstad, Einar; Tøndel, Camilla (Journal article; Peer reviewed, 2021)
      Measurement of glomerular filtration rate (GFR) in children by iohexol injection and blood sampling from the contralateral arm is widely used. A single intravenous access for iohexol injection and subsequent blood sampling ...
    • AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study 

      Hong, Yu; Liang, Kristina Xiao; Gilhus, Nils Erik (Journal article; Peer reviewed, 2020-07-08)
      Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, ...
    • Atlantic salmon and sea trout display synchronised smolt migration relative to linked environmental cues 

      Harvey, Alison C.; Glover, Kevin; Wennevik, Vidar; Skaala, Øystein (Journal article; Peer reviewed, 2020)
      Anadromous salmon and sea trout smolts face challenging migrations from freshwater to the marine environment characterised by high mortality. Therefore, the timing of smolt migration is likely to be critical for survival. ...
    • Automated segmentation of endometrial cancer on MR images using deep learning 

      Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Solteszova, Veronika; Zanna, Antonella; Fasmer, Kristine Eldevik; Krakstad, Camilla; Lundervold, Arvid; Lundervold, Alexander Selvikvåg; Salvesen, Øyvind; Erickson, Bradley J.; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ...
    • Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer 

      Krüger, Kristi; Silwal-Pandit, Laxmi; Wik, Elisabeth; Straume, Oddbjørn; Stefansson, Ingunn Marie; Borgen, Elin; Garred, Øystein; Naume, Bjørn; Engebråten, Olav; Akslen, Lars Andreas (Journal article; Peer reviewed, 2021)
      A subset of breast cancer patients benefits from preoperative bevacizumab and chemotherapy, but validated predictive biomarkers are lacking. Here, we aimed to evaluate tissue-based angiogenesis markers for potential ...
    • Best humans still outperform artificial intelligence in a creative divergent thinking task 

      Koivisto, Mika; Grassini, Simone (Journal article; Peer reviewed, 2023)
      Creativity has traditionally been considered an ability exclusive to human beings. However, the rapid development of artificial intelligence (AI) has resulted in generative AI chatbots that can produce high-quality artworks, ...
    • Brain solute transport is more rapid in periarterial than perivenous spaces 

      Vinje, Vegard; Bakker, Erik N. T. P.; Rognes, Marie Elisabeth (Journal article; Peer reviewed, 2021)
      Fluid flow in perivascular spaces is recognized as a key component underlying brain transport and clearance. An important open question is how and to what extent differences in vessel type or geometry affect perivascular ...
    • Brain‑correlates of processing local dependencies within a statistical learning paradigm 

      Tsogli, Vera; Skouras, Stavros; Koelsch, Stefan (Journal article; Peer reviewed, 2022)
      Statistical learning refers to the implicit mechanism of extracting regularities in our environment. Numerous studies have investigated the neural basis of statistical learning. However, how the brain responds to violations ...
    • CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation 

      McKerr, Niamh; Mohd-Sarip, Adone; Dorrian, Hannah; Breen, Conor; A. James, Jacqueline; McQuaid, Stephen; Mills, Ian Geoffrey; McCloskey, Karen D. (Journal article; Peer reviewed, 2023)
      Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding CaV1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and CaV1.3 ...
    • Century-long cod otolith biochronology reveals individual growth plasticity in response to temperature 

      Smolinski, Szymon; Deplanque-Lasserre, Julie; Hjörleifsson, Einar; Geffen, Audrey J.; Godiksen, Jane Aanestad; Campana, Steven E. (Journal article; Peer reviewed, 2020)
      Otolith biochronologies combine growth records from individual fish to produce long-term growth sequences, which can help to disentangle individual from population-level responses to environmental variability. This study ...
    • Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis 

      Mosleth, Ellen Færgestad; Vedeler, Christian Alexander; Liland, Kristian Hovde; McLeod, Anette; Bringeland, Gerd Haga; Kroondijk, Liesbeth; Berven, Frode Steingrimsen; Lysenko, Artem; Rawlings, Christopher J.; El-Hajj Eid, Karim; Opsahl, Jill Anette; Gjertsen, Bjørn Tore; Myhr, Kjell-Morten; Gavasso, Sonia (Journal article; Peer reviewed, 2021-02-18)
      Despite intensive research, the aetiology of multiple sclerosis (MS) remains unknown. Cerebrospinal fluid proteomics has the potential to reveal mechanisms of MS pathogenesis, but analyses must account for disease ...
    • Changes in the gene expression profile during spontaneous migraine attacks 

      Kogelman, Lisette J.A.; Falkenberg, Katrine; Buil, Alfonso; Erola, Pau; Courraud, Julie; Laursen, Susan Svane; Michoel, Tom Luk Robert; Olesen, Jes; Hansen, Thomas F. (Journal article; Peer reviewed, 2021)
      Migraine attacks are delimited, allowing investigation of changes during and outside attack. Gene expression fluctuates according to environmental and endogenous events and therefore, we hypothesized that changes in RNA ...
    • Characterization of Pseudoterranova ceticola (Nematoda: Anisakidae) larvae from meso/bathypelagic fishes off Macaronesia (NW Africa waters) 

      Bao, Miguel; Olsen, Kaja M.; Levsen, Arne; Cipriani, Paolo; Giulietti, Lucilla; Storesund, Julia Endresen; García-Seoane, Eva; Karlsbakk, Egil Erlingsson (Journal article; Peer reviewed, 2022)
      The genus Pseudoterranova includes parasite species of cetaceans and pinnipeds. The third stage larva (L3) of seal-infecting species occur in second intermediate or paratenic fish hosts mainly in neritic waters. This study ...
    • The chemical defensome of five model teleost fish 

      Eide, Marta; Zhang, Xiaokang; Karlsen, Odd André; Goldstone, Jared V.; Stegeman, John; Jonassen, Inge; Goksøyr, Anders (Journal article; Peer reviewed, 2021)
      How an organism copes with chemicals is largely determined by the genes and proteins that collectively function to defend against, detoxify and eliminate chemical stressors. This integrative network includes receptors and ...
    • Cognitive and MRI trajectories for prediction of Alzheimer’s disease 

      Abolpour Mofrad, Samaneh; Lundervold, Astri Johansen; Vik, Alexandra; Lundervold, Alexander Selvikvåg (Journal article; Peer reviewed, 2021)
      The concept of Mild Cognitive Impairment (MCI) is used to describe the early stages of Alzheimer’s disease (AD), and identification and treatment before further decline is an important clinical task. We selected longitudinal ...
    • Cognitive function and brain plasticity in a rat model of shift work: role of daily rhythms, sleep and glucocorticoids 

      Marti, Andrea Rørvik; Pedersen, Torhild; Wisor, Jonathan P.; Mrdalj, Jelena; Holmelid, Øystein; Patil, Sudarshan; Meerlo, Peter; Bramham, Clive R.; Grønli, Janne (Journal article; Peer reviewed, 2020)
      Many occupations require operations during the night-time when the internal circadian clock promotes sleep, in many cases resulting in impairments in cognitive performance and brain functioning. Here, we use a rat model ...
    • Coherent electron displacement for quantum information processing using attosecond single cycle pulses 

      Agueny, Hicham (Journal article; Peer reviewed, 2020)
      Coherent electron displacement is a conventional strategy for processing quantum information, as it enables to interconnect distinct sites in a network of atoms. The efficiency of the processing relies on the precise control ...
    • COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1 

      Dankel, Simon N; Grytten, Elise; Bjune, Jan-Inge; Nielsen, Hans Jørgen; Dietrich, Arne; Blüher, Matthias; Sagen, Jørn V.; Mellgren, Gunnar (Journal article; Peer reviewed, 2020)
      Fibrillar collagen COL6α3 in adipose tissue has been associated with obesity, inflammation, insulin resistance and cancer. We here aimed to identify novel transcriptional regulators of COL6A3 expression. Based on a ...