dc.contributor.author | Næsgaard, Patrycja | en_US |
dc.contributor.author | Fuente, Ricardo León de la | en_US |
dc.contributor.author | Nilsen, Stein Tore | en_US |
dc.contributor.author | Woie, Leik | en_US |
dc.contributor.author | Årsland, Torbjørn | en_US |
dc.contributor.author | Staines, Harry | en_US |
dc.contributor.author | Nilsen, Dennis W.T. | en_US |
dc.date.accessioned | 2016-08-02T09:13:04Z | |
dc.date.available | 2016-08-02T09:13:04Z | |
dc.date.issued | 2013 | |
dc.Published | Cardiology Research and Practice 2013, 2013:398034 | eng |
dc.identifier.issn | 2090-0597 | |
dc.identifier.uri | https://hdl.handle.net/1956/12381 | |
dc.description.abstract | Vitamin D may not only reflect disease but may also serve as a prognostic indicator. Our aim was to assess the gender-specific utility of vitamin D measured as 25-hydroxy-vitamin D [25(OH)D] to predict all-cause and cardiac death in patients with suspected acute coronary syndrome (ACS) and to compare its prognostic utility to brain natriuretic peptide (BNP) and high-sensitivity C-reactive protein (hsCRP). Blood samples were harvested on admission in 982 patients. Forty percent were women (65.9 ± 12.6 years). Mortality was evaluated in quartiles of 25(OH)D, BNP, and hsCRP, respectively, during a 5-year follow-up, applying univariate and multivariate analyses. One hundred and seventy-three patients died; 78 were women. In 92 patients (37 women), death was defined as cardiac. In women, the univariate hazard ratio (HR) for total death of 25(OH)D in Quartile (Q) 2 versus Q1, Q3 versus Q1, and Q4 versus Q1 was 0.55 (95% CI 0.33–0.93), 0.29 (95% CI 0.15–0.55), and 0.13 (95% CI 0.06–0.32), respectively. In females, it was an independent predictor of total and cardiac death, whereas BNP and hsCRP were less gender-specific. No gender differences in 25(OH)D were noted in a reference material. Accordingly, vitamin D independently predicts mortality in females with suspected ACS. | en_US |
dc.language.iso | eng | eng |
dc.publisher | Hindawi | eng |
dc.rights | Attribution CC BY | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/ | eng |
dc.title | Vitamin D predicts all-cause and cardiac mortality in females with suspected acute coronary syndrome: a comparison with brain natriuretic peptide and high-sensitivity C-reactive protein | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2016-04-11T12:46:47Z | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2013 The Authors | |
dc.identifier.doi | https://doi.org/10.1155/2013/398034 | |
dc.identifier.cristin | 1074472 | |
dc.relation.project | Egen institusjon: ClinicalTrials.gov Identifier: NCT01377402 | |
dc.subject.nsi | VDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771 | |
dc.subject.nsi | VDP::Midical sciences: 700::Clinical medical sciences: 750::Cardiology: 771 | |