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dc.contributor.authorBerge, Line Idenen_US
dc.contributor.authorSkogen, Jens Christofferen_US
dc.contributor.authorSulo, Gerharden_US
dc.contributor.authorIgland, Jannickeen_US
dc.contributor.authorWilhelmsen, Ingvarden_US
dc.contributor.authorVollset, Stein Emilen_US
dc.contributor.authorTell, Grethe S.en_US
dc.contributor.authorKnudsen, Ann Kristinen_US
dc.date.accessioned2017-05-02T11:31:10Z
dc.date.available2017-05-02T11:31:10Z
dc.date.issued2016
dc.PublishedBerge LI, Skogen JC, Sulo G, Igland J, Wilhelmsen IWI, Vollset SE, Tell GST, Knudsen AK. Health anxiety and risk of ischaemic heart disease: A prospective cohort study linking the Hordaland Health Study (HUSK) with the Cardiovascular Diseases in Norway (CVDNOR) project. BMJ Open. 2016;6(11):e012914eng
dc.identifier.issn2044-6055
dc.identifier.urihttps://hdl.handle.net/1956/15765
dc.description.abstractBackground: The risk of ischaemic heart disease (IHD) is largely influenced by lifestyle. Interestingly, cohort studies show that anxiety in general is associated with increased risk of IHD, independent of established risk factors for cardiovascular disease. Health anxiety is a specific type of anxiety characterised by preoccupation of having, acquiring or possibly avoiding illness, yet little is known about lifestyle and risk of disease development in this group. Aim: Investigate whether health anxiety is prospectively associated with IHD, and whether a potential association can be explained by the presence or absence of established risk factors for cardiovascular diseases. Methods: Incident IHD was studied among 7052 participants in the community-based Hordaland Health Study (HUSK) during 12 years follow-up by linkage to the Cardiovascular Diseases in Norway (CVDNOR) project. Scores above 90th centile of the Whiteley Index defined health anxiety cases. Associations were examined with the Cox proportional regression models. Results: During follow-up, 6.1% of health anxiety cases developed IHD compared with 3.0% of noncases, yielding a gender-adjusted HR of 2.12 (95% CI 1.52 to 2.95). After adjustments for established cardiovascular risk factors, about 70% increased risk of IHD was found among cases with health anxiety (HR: 1.73 (95% CI 1.21 to 2.48)). The association followed a dose–response pattern. Conclusions: This finding corroborates and extends the understanding of anxiety in various forms as a risk factor for IHD. New evidence of negative consequences over time underlines the importance of proper diagnosis and treatment for health anxiety.en_US
dc.language.isoengeng
dc.publisherBMJeng
dc.relation.urihttp://bmjopen.bmj.com/content/bmjopen/6/11/e012914.full.pdf
dc.rightsAttribution CC BY-NCeng
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/eng
dc.titleHealth anxiety and risk of ischaemic heart disease: A prospective cohort study linking the Hordaland Health Study (HUSK) with the Cardiovascular Diseases in Norway (CVDNOR) projecten_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2017-02-10T09:15:18Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2016 The Author(s)
dc.identifier.doihttps://doi.org/10.1136/bmjopen-2016-012914
dc.identifier.cristin1415022
dc.source.journalBMJ Open


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