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dc.contributor.authorBunæs, Dagmar Fossåen_US
dc.contributor.authorLie, Stein Atleen_US
dc.contributor.authorÅstrøm, Anne Nordrehaugen_US
dc.contributor.authorMustafa, Kamal Babikeir Elnen_US
dc.contributor.authorLeknes, Knut N.en_US
dc.PublishedBunæs DFB, Lie SA, Åstrøm AN, Mustafa KBE, Leknes KN. Site-specific treatment outcome in smokers following 12 months of supportive periodontal therapy. Journal of Clinical Periodontology. 2016;43(12):1086-1093eng
dc.description.abstractAim: To evaluate the effect of cigarette smoking on periodontal health at patient, tooth, and site levels following supportive therapy. Materials and Methods: Eighty chronic periodontitis patients, 40 smokers and 40 non-smokers, were recruited to a single-arm clinical trial. Periodontal examinations were performed at baseline (T0), 3 months following active periodontal therapy (T1), and 12 months following supportive periodontal therapy (T2). Smoking status was validated measuring serum cotinine levels. Probing depth (PD) ≥ 5 mm with bleeding on probing (BoP) was defined as the primary outcome. Logistic regression analyses adjusted for clustered observations of patients, teeth, and sites and mixed effects models were employed to analyse the data. Results: All clinical parameters improved from T0 to T2 (p < 0.001), whereas PD, bleeding index (BI), and plaque index (PI) increased from T1 to T2 in smokers and non-smokers (p < 0.001). An overall negative effect of smoking was revealed at T2 (OR = 2.78, CI: 1.49, 5.18, p < 0.001), with the most pronounced effect at maxillary single-rooted teeth (OR = 5.08, CI: 2.01, 12.78, p < 0.001). At the patient level, less variation in treatment outcome was detected within smokers (ICC = 0.137) compared with non-smokers (ICC = 0.051). Conclusion: Smoking has a negative effect on periodontal health following 12 months of supportive therapy, in particular at maxillary single-rooted teeth.en_US
dc.relation.ispartof<a href="" target="blank"> Outcomes of Periodontal Therapy in Smokers and Non-smokers with Chronic Periodontitis</a>
dc.rightsAttribution CC BY-NC-NDeng
dc.subjectChronic periodontitiseng
dc.subjectmultilevel analysiseng
dc.subjectperiodontal therapyeng
dc.titleSite-specific treatment outcome in smokers following 12 months of supportive periodontal therapyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2016 The Author(s)
dc.source.journalJournal of Clinical Periodontology

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