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Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis. Specific Immunity in Young Children

dc.contributor.authorJenum, Synneen_US
dc.contributor.authorSivakumaran, Dhanasekaranen_US
dc.contributor.authorRitz, Christianen_US
dc.contributor.authorMacaden, Ren_US
dc.contributor.authorDoherty, TMen_US
dc.contributor.authorGrewal, Harleenen_US
dc.contributor.authorTB Trials Study, Groupen_US
dc.date.accessioned2017-06-09T13:15:13Z
dc.date.available2017-06-09T13:15:13Z
dc.date.issued2016
dc.PublishedJenum S, Sivakumaran D, Ritz C, Macaden R, Doherty T, Grewal H, TB Trials Study. Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis. Specific Immunity in Young Children. The Pediatric Infectious Disease Journal. 2016;35(12):1336-1338eng
dc.identifier.issn0891-3668
dc.identifier.urihttps://hdl.handle.net/1956/15959
dc.description.abstractWe have explored the added value of interferon-γ (IFNγ)– inducible protein 10 as a read-out of Mycobacterium tuberculosis–specific immunity in young Indian children, where the sensitivity of the IFNγ release assays for tuberculosis is poor. Reduced frequency of indeterminate results and an increased sensitivity for tuberculosis suggest a potential for fewer missed cases with a combined IFNγ/inducible protein 10 read-out in a 4th generation IFNγ release assays.en_US
dc.language.isoengeng
dc.publisherWolters Kluwereng
dc.rightsAttribution CC BY-NC-NDeng
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/eng
dc.subjectTuberculosiseng
dc.subjectChildeng
dc.subjecttuberculin skin testeng
dc.subjectinterferon-γ release assayeng
dc.subjectCytokineseng
dc.subjectchemokineseng
dc.titleAdded Value of IP-10 as a Read-Out of Mycobacterium tuberculosis. Specific Immunity in Young Childrenen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2017-05-08T12:12:08Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2016 Wolters Kluwer Health, Inc
dc.identifier.doihttps://doi.org/10.1097/inf.0000000000001328
dc.identifier.cristin1392265
dc.source.journalThe Pediatric Infectious Disease Journal


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