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dc.contributor.authorWiig, Ulrikke S.en_US
dc.contributor.authorZahl, Sverre Mortenen_US
dc.contributor.authorEgge, Arilden_US
dc.contributor.authorHelseth, Eiriken_US
dc.contributor.authorWester, Knuten_US
dc.PublishedWiig, Zahl SM, Egge A, Helseth E, Wester K. Epidemiology of benign external hydrocephalus in Norway - a population-based study. Pediatric Neurology. 2017;73:36-41eng
dc.description.abstractBackground: Benign external hydrocephalus is defined as a rapidly increasing head circumference (occipitofrontal circumference) with characteristic radiological findings of increased subarachnoid cerebrospinal fluid spaces on neuroimaging. The incidence of benign external hydrocephalus has not been previously reported, and there is no available information on the ratio of benign external hydrocephalus in the population of hydrocephalic children. Methods: This study is retrospective and population-based study, geographically covering two health regions in the southern half of Norway with a total mean population of 3.34 million in the ten-year study period, constituting approximately 75% of the Norwegian population. Children with a head circumference crossing two percentiles, or greater than the 97.5th percentile, and with typical imaging findings of enlarged frontal subarachnoid spaces with or without enlarged ventricles were included. Children were excluded if they had a history of head trauma, intracranial hemorrhage, central nervous system infection, other known causes of hydrocephalus, or were born preterm defined as birth before 37 weeks of gestation. Results: A total of 176 children fitting the criteria were identified, giving an incidence of 0.4 per 1000 live births. One hundred fifty-two (86.4%) of the patients were male, and mean age at referral was 7.3 months. Increasing head circumference was the main reason for referral in 158 (89.8%) patients and the only finding in 60 (34.1%) patients. Thirty-seven (21%) children had normal ventricles on imaging; the remainder had increased ventricular size. The incidence of pediatric hydrocephalus in Norway is reported to be 0.75 per 1000 live births, thus benign external hydrocephalus accounts for approximately 50% of hydrocephalic conditions in this population. Conclusions: The incidence of benign external hydrocephalus was found to be 0.4 per 1000 live births in this population.en_US
dc.rightsAttribution CC BY-NC-NDeng
dc.subjectbenign external hydrocephaluseng
dc.subjecthead circumferenceeng
dc.titleEpidemiology of benign external hydrocephalus in Norway - a population-based studyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2017 The Author(s)
dc.source.journalPediatric Neurology

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