Show simple item record

dc.contributor.authorNæsgaard, Patrycjaen_US
dc.contributor.authorGrundt, Heidien_US
dc.contributor.authorNordøy, Arneen_US
dc.contributor.authorStaines, Harryen_US
dc.contributor.authorNilsen, Dennis W.T.en_US
dc.PublishedNæsgaard P, Grundt H, Nordøy a, Staines H, Nilsen DW. Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction. Frontiers in Cardiovascular Medicine. 2017;4:41eng
dc.description.abstractBackground: Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce. Objectives: We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. Methods: 228 patients were randomized 1:1 to receive a daily dose of either 4 g omega-3 (OMACOR®) or an equal dose of corn oil, administered double-blindly for 12 months. Total omega-3 and omega-6 measurements were available in 40 randomly picked patients. Results: There was no significant intergroup difference in 25(OH)D changes at 12 months follow-up (p = 0.12), but there was a minor statistical significant intragroup increase in 25(OH)D in both intervention arms (p < 0.001 for n-3 polyunsaturated fatty acids and p = 0.013 for corn oil, respectively). A positive correlation was noted between 25(OH)D and omega-3 prior to inclusion; r = 0.418, p = 0.007, attenuated at 12 months by purified omega-3 intervention; r = 0.021, p = 0.93. No positive correlation was observed between omega-6 and 25(OH)D. Conclusion: Long-term treatment with a high dose of purified omega-3 as compared to corn oil did not improve serum concentrations of vitamin D.en_US
dc.rightsAttribution CC BYeng
dc.subjectvitamin Deng
dc.subjectacute myocardial infarctioneng
dc.subject25-hydroxyvitamin Deng
dc.titleVitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarctionen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2017 The Author(s)
dc.source.journalFrontiers in Cardiovascular Medicine
dc.subject.nsiVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771
dc.subject.nsiVDP::Midical sciences: 700::Clinical medical sciences: 750::Cardiology: 771

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution CC BY
Except where otherwise noted, this item's license is described as Attribution CC BY