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dc.contributor.authorJull, Janet E.G.en_US
dc.contributor.authorWhitehead, Margareten_US
dc.contributor.authorPetticrew, Marken_US
dc.contributor.authorKristjansson, Elizabethen_US
dc.contributor.authorGough, Daviden_US
dc.contributor.authorPetkovic, Jenniferen_US
dc.contributor.authorVolmink, Jimmyen_US
dc.contributor.authorWeijer, Charlesen_US
dc.contributor.authorTaljaard, Monicaen_US
dc.contributor.authorEdwards, Sarah Jane L.en_US
dc.contributor.authorMbuagbaw, Lawrenceen_US
dc.contributor.authorCookson, Richarden_US
dc.contributor.authorMcGowan, Jessie L.en_US
dc.contributor.authorLyddiatt, Anneen_US
dc.contributor.authorBoyer, Yvonneen_US
dc.contributor.authorCuervo, Luis Gabrielen_US
dc.contributor.authorArmstrong, Rebeccaen_US
dc.contributor.authorWhite, Howarden_US
dc.contributor.authorYoganathan, Manosilaen_US
dc.contributor.authorPantoja, Tomásen_US
dc.contributor.authorShea, Beverley J.en_US
dc.contributor.authorPottie, Kevinen_US
dc.contributor.authorNorheim, Ole Frithjofen_US
dc.contributor.authorBaird, Sarahen_US
dc.contributor.authorRobberstad, Bjarneen_US
dc.contributor.authorSommerfelt, Halvoren_US
dc.contributor.authorAsada, Yukikoen_US
dc.contributor.authorWells, George A.en_US
dc.contributor.authorTugwell, Peteren_US
dc.contributor.authorWelch, Vivianen_US
dc.PublishedJull, Whitehead M, Petticrew M, Kristjansson E, Gough D, Petkovic J, Volmink J, Weijer, Taljaard M, Edwards, Mbuagbaw L, Cookson R, McGowan, Lyddiatt A, Boyer, Cuervo LG, Armstrong, White H, Yoganathan, Pantoja, Shea, Pottie K, Norheim OF, Baird, Robberstad B, Sommerfelt H, Asada Y, Wells GA, Tugwell P, Welch V. When is a randomised controlled trial health equity relevant? Development and validation of a conceptual framework. BMJ Open. 2017;7(9)eng
dc.description.abstractBackground Randomised controlled trials can provide evidence relevant to assessing the equity impact of an intervention, but such information is often poorly reported. We describe a conceptual framework to identify health equity-relevant randomised trials with the aim of improving the design and reporting of such trials. Methods An interdisciplinary and international research team engaged in an iterative consensus building process to develop and refine the conceptual framework via face-to-face meetings, teleconferences and email correspondence, including findings from a validation exercise whereby two independent reviewers used the emerging framework to classify a sample of randomised trials. Results A randomised trial can usefully be classified as ‘health equity relevant’ if it assesses the effects of an intervention on the health or its determinants of either individuals or a population who experience ill health due to disadvantage defined across one or more social determinants of health. Health equity-relevant randomised trials can either exclusively focus on a single population or collect data potentially useful for assessing differential effects of the intervention across multiple populations experiencing different levels or types of social disadvantage. Trials that are not classified as ‘health equity relevant’ may nevertheless provide information that is indirectly relevant to assessing equity impact, including information about individual level variation unrelated to social disadvantage and potentially useful in secondary modelling studies. Conclusion The conceptual framework may be used to design and report randomised trials. The framework could also be used for other study designs to contribute to the evidence base for improved health equity.en_US
dc.publisherBMJ Publishing Group Ltd.eng
dc.rightsCC BY-NC 4.0eng
dc.titleWhen is a randomised controlled trial health equity relevant? Development and validation of a conceptual frameworken_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright The Author(s) 2017
dc.source.journalBMJ Open

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