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dc.contributor.authorRajalingam, Dhaksshaginy
dc.contributor.authorJacobsen, Daniel Pitz
dc.contributor.authorNielsen, Morten Birkeland
dc.contributor.authorEinarsen, Ståle
dc.contributor.authorGjerstad, Johannes
dc.date.accessioned2020-02-17T13:40:55Z
dc.date.available2020-02-17T13:40:55Z
dc.date.issued2019-05-24
dc.PublishedRajalingam D, Jacobsen DP, Nielsen MB, Einarsen S, Gjerstad J. Exposure to workplace bullying, distress, and insomnia. The moderating role of the miR-146a genotype. Frontiers in Psychology. 2019;10:1204.eng
dc.identifier.issn1664-1078
dc.identifier.urihttps://hdl.handle.net/1956/21426
dc.description.abstractSeveral lines of evidence show that systematic exposure to negative social acts at the workplace i.e., workplace bullying, results in symptoms of depression and anxiety among those targeted. However, little is known about the association between bullying, inflammatory genes and sleep problems. In the present study, we examined the indirect association between exposure to negative social acts and sleep through distress, as moderated by the miR-146a genotype. The study was based on a nationally representative survey of 1179 Norwegian employees drawn from the Norwegian Central Employee Register by Statistics Norway. Exposure to workplace bullying was measured with the 9-item version of Negative Acts Questionnaire – Revised (NAQ-R) inventory. Seventeen items from Hopkins Symptom Checklist (HSCL-25) was used to measure distress. Insomnia was assessed with three items reflecting problems with sleep onset, maintenance of sleep and early morning awakening. Genotyping with regard to miR146a rs2910164, previously linked to inflammatory processes, was carried out using Taqman assay. The data revealed that individuals systematically exposed to negative social acts at the workplace reported higher levels of sleep problems than non-exposed individuals. Moreover, the relationship between distress induced by exposure to negative social acts and insomnia was significantly stronger for individuals with the miR-146a GG genotype. Thus, the miR-146a genotype moderated the association between distress and insomnia among individuals exposed to negative social acts. The present report support the hypothesis that inflammation could play a role in stress-induced insomnia among individuals exposed to workplace bullying.en_US
dc.language.isoengeng
dc.publisherFrontierseng
dc.rightsAttribution CC BY 4.0eng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/eng
dc.subjectBullyingeng
dc.subjectDistresseng
dc.subjectInsomniaeng
dc.subjectGenotypeeng
dc.subjectmiR-146aeng
dc.subjectrs2910164eng
dc.titleExposure to workplace bullying, distress, and insomnia. The moderating role of the miR-146a genotypeeng
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2019-08-22T11:17:55Z
dc.description.versionpublishedVersion
dc.rights.holderCopyright 2019 Rajalingam, Jacobsen, Nielsen, Einarsen and Gjerstad.eng
dc.identifier.doihttps://doi.org/10.3389/fpsyg.2019.01204
dc.identifier.cristin1704212
dc.source.journalFrontiers in Psychology


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