Show simple item record

dc.contributor.authorBorgen, Tove Tveitanen_US
dc.contributor.authorBjørnerem, Åshilden_US
dc.contributor.authorSolberg, Lene Bergendalen_US
dc.contributor.authorAndreasen, Camillaen_US
dc.contributor.authorFigved, Wenderen_US
dc.contributor.authorHübschle, Lars Michaelen_US
dc.contributor.authorStenbro, May-Britten_US
dc.contributor.authorBasso, Trudeen_US
dc.contributor.authorDahl, cecilieen_US
dc.contributor.authorStutzer, Jens-Meinharden_US
dc.contributor.authorFrihagen, Fredeen_US
dc.contributor.authorEriksen, Erik Finken_US
dc.contributor.authorNordsletten, Larsen_US
dc.contributor.authorHansen, Ann Kristinen_US
dc.contributor.authorApalset, Ellen Margreteen_US
dc.contributor.authorGjertsen, Jan Eriken_US
dc.contributor.authorLund, Idaen_US
dc.PublishedBorgen, Bjørnerem Å, Solberg, Andreasen C, Figved, Hübschle, Stenbro, Basso T, Dahl, Stutzer, Frihagen, Eriksen, Nordsletten, Hansen, Apalset, Gjertsen, Lund. Determinants of trabecular bone score and prevalent vertebral. Osteoporosis International. 2020;31:505–514eng
dc.description.abstractSummary: Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, alcohol intake and BMD, not SQ1–SQ3 fractures. SQ1–SQ3 fractures were associated with age, prior fractures, and lumbar spine BMD, but not TBS. Introduction: Trabecular bone score (TBS) and vertebral fractures assessed by semiquantitative method (SQ1–SQ3) seem to reflect different aspects of bone strength. We therefore sought to explore the determinants of and the associations between TBS and SQ1–SQ3 fractures. Methods: This cross-sectional sub-study of the Norwegian Capture the Fracture Initiative included 496 women aged ≥ 50 years with fragility fractures. All responded to a questionnaire about risk factors for fracture, had bone mineral density (BMD) of femoral neck and/or lumbar spine assessed, TBS calculated, and 423 had SQ1–SQ3 fracture assessed. Results: Mean (SD) age was 65.6 years (8.6), mean TBS 1.27 (0.10), and 33.3% exhibited SQ1–SQ3 fractures. In multiple variable analysis, higher age (βper SD = − 0.26, 95% CI: − 0.36,− 0.15), parental hip fracture (β = − 0.29, 95% CI: − 0.54,− 0.05), and daily alcohol intake (β = − 0.43, 95% CI − 0.79, − 0.08) were associated with lower TBS. Higher BMD of femoral neck (βper SD = 0.34, 95% CI 0.25–0.43) and lumbar spine (βper SD = 0.40, 95% CI 0.31–0.48) were associated with higher TBS. In multivariable logistic regression analyses, age (ORper SD = 1.94, 95% CI 1.51–2.46) and prior fragility fractures (OR = 1.71, 95% CI 1.09–2.71) were positively associated with SQ1–SQ3 fractures, while lumbar spine BMD (ORper SD = 0.75 95% CI 0.60–0.95) was negatively associated with SQ1–SQ3 fractures. No association between TBS and SQ1–SQ3 fractures was found. Conclusion: Since TBS and SQ1–SQ3 fractures were not associated, they may act as independent risk factors, justifying the use of both in post-fracture risk assessment.en_US
dc.rightsAttribution CC BYeng
dc.titleDeterminants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACTen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2019 The Authors
dc.source.journalOsteoporosis International

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution CC BY
Except where otherwise noted, this item's license is described as Attribution CC BY