Browsing Sars International Centre for Marine Molecular Biology by Author "Richards, Gemma Sian"

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NvPOU4/Brain3 Functions as a Terminal Selector Gene in the Nervous System of the Cnidarian Nematostella vectensis

Tourniere, Oceane Barbara; Dolan, David William Peter; Richards, Gemma Sian; Sunagar, Kartik; Columbus-Shenkar, Yaara Y; Moran, Yehu; Rentzsch, Fabian (Journal article; Peer reviewed, 2020-03)

Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that characterize distinct cell types. Here, we show that, in the sea anemone Nematostella vectensis, NvPOU4 ...
NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis

Lemaitre, Quentin Indiana Bruno; Bartsch, Natascha; Kouzel, Ivan; Busengdal, Henriette; Richards, Gemma Sian; Steinmetz, Patrick; Rentzsch, Fabian (Journal article; Peer reviewed, 2023)

Neurogenesis has been studied extensively in the ectoderm, from which most animals generate the majority of their neurons. Neurogenesis from non-ectodermal tissue is, in contrast, poorly understood. Here we use the cnidarian ...
Regulation of Nematostella neural progenitors by SoxB, Notch and bHLH genes

Richards, Gemma Sian; Rentzsch, Fabian (Journal article; Peer reviewed, 2015-10-06)

Notch signalling, SoxB and Group A bHLH ‘proneural’ genes are conserved regulators of the neurogenic program in many bilaterians. However, the ancestry of their functions and interactions is not well understood. We address ...