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dc.contributor.authorDahle, Håkoneng
dc.contributor.authorHannisdal, Bjarteeng
dc.contributor.authorSteinsbu, Bjørn Olaveng
dc.contributor.authorOmmedal, Hegeeng
dc.contributor.authorEinen, Jørneng
dc.contributor.authorJensen, Sigmundeng
dc.contributor.authorLarsen, Øyvindeng
dc.contributor.authorØvreås, Liseeng
dc.contributor.authorNorland, Sveineng
dc.PublishedExtremophiles 15(4): 509-516en
dc.description.abstractQuantitative characterization of the mode and rate of phenotypic evolution is rarely applied to prokaryotes. Here, we present an analysis of temperature optimum (Topt) evolution in the thermophilic family Thermotogaceae, which has a large number of cultured representatives. We use log-rate-interval analysis to show that Topt evolution in Thermotogaceae is consistent with a Brownian motion (BM) evolutionary model. The properties of the BM model are used to a establish confidence intervals on the unknown phenotypic trait value of an uncultured organism, given its distance to a close relative with known trait value. Cross-validation by bootstrapping indicates that the predictions are robust.en_US
dc.subjectUltrasonographic imagingeng
dc.titleEvolution of temperature optimum in Thermotogaceae and the prediction of trait values of uncultured organismsen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holder©The Author(s) 2011en_US
dc.subject.nsiVDP::Mathematics and natural science: 400::Zoology and botany: 480en_US

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