Show simple item record

dc.contributor.authorSolheim, Eivinden_US
dc.contributor.authorOff, Morten Kristianen_US
dc.contributor.authorHoff, Per Ivaren_US
dc.contributor.authorDe Bortoli, Alessandroen_US
dc.contributor.authorSchuster, Peteren_US
dc.contributor.authorOhm, Ole-Jørgenen_US
dc.contributor.authorChen, Jianen_US
dc.date.accessioned2011-11-23T12:39:39Z
dc.date.available2011-11-23T12:39:39Z
dc.date.issued2011-04-08eng
dc.PublishedJournal of Interventional Cardiac Electrophysiology 32(1): 37-43en
dc.identifier.issn1383-875X
dc.identifier.urihttps://hdl.handle.net/1956/5222
dc.description.abstractBackground A remote magnetic navigation (MN) system is available for radiofrequency ablation of atrial fibrillation (AF), challenging the conventional manual ablation technique. The myocardial markers were measured to compare the effects of the two types of MN catheters with those of a manual-irrigated catheter in AF ablation. Methods AF patients underwent an ablation procedure using either a conventional manual-irrigated catheter (CIR, n=65) or an MN system utilizing either an irrigated (RMI, n=23) or non-irrigated catheter (RMN, n=26). Levels of troponin T (TnT) and the cardiac isoform of creatin kinase (CKMB) were measured before and after ablation. Results Mean procedure times and total ablation times were longer employing the remote magnetic system. In all groups, there were pronounced increases in markers of myocardial injury after ablation, demonstrating a significant correlation between total ablation time and post-ablation levels of TnT and CKMB (CIR r=0.61 and 0.53, p<0.001; RMI r=0.74 and 0.73, p<0.001; and RMN r=0.51 and 0.59, p<0.01). Time-corrected release of TnT was significantly higher in the CIR group than in the other groups. Of the patients, 59.6% were free from AF at follow-up (12.2± 5.4 months) and there were no differences in success rate between the three groups. Conclusions Remote magnetic catheters may create more discrete and predictable ablation lesions measured by myocardial enzymes and may require longer total ablation time to reach the procedural endpoints. Remote magnetic non-irrigated catheters do not appear to be inferior to magnetic irrigated catheters in terms of myocardial enzyme release and clinical outcome.en_US
dc.language.isoengeng
dc.publisherSpringereng
dc.relation.ispartof<a href="http://hdl.handle.net/1956/5363" target="blank">Radiofrequency ablation of atrial fibrillation. Clinical results and studies of mechanisms</a>eng
dc.rights.urihttp://www.springer.com/open+access/open+choice?SGWID=0-40359-0-0-0eng
dc.subjectAtrial fibrillationeng
dc.subjectMyocardial markerseng
dc.subjectMagnetic navigationeng
dc.subjectIrrigated cathetereng
dc.titleRemote magnetic versus manual catheters: evaluation of ablation effect in atrial fibrillation by myocardial marker levelsen_US
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright the Author(s) 2011
dc.identifier.doihttps://doi.org/10.1007/s10840-011-9567-z
dc.subject.nsiVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Cardiology: 771eng


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record