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dc.contributor.authorJoensen, Jonen_US
dc.contributor.authorØvsthus, Knuten_US
dc.contributor.authorReed, Rolf K.en_US
dc.contributor.authorHummelsund, Steinaren_US
dc.contributor.authorIversen, Vegard Vereideen_US
dc.contributor.authorLopes-Martins, Rodrigo Álvaro Brandãoen_US
dc.contributor.authorBjordal, Jan Magnusen_US
dc.date.accessioned2013-10-30T13:38:24Z
dc.date.available2013-10-30T13:38:24Z
dc.date.issued2012-11-26eng
dc.PublishedPhotomedicine and Laser Surgery 30(12): 688-694eng
dc.identifier.issn1549-5418
dc.identifier.urihttps://hdl.handle.net/1956/7460
dc.descriptionThis is a copy of an article published in the Photomedicine and Laser Surgery © 2012 copyright Mary Ann Liebert, Inc.; Photomedicine and Laser Surgery is available online at: http://online.liebertpub.comeng
dc.description.abstractObjective: The purpose of this study was to investigate the rat skin penetration abilities of two commercially available low-level laser therapy (LLLT) devices during 150 sec of irradiation. Background data: Effective LLLT irradiation typically lasts from 20 sec up to a few minutes, but the LLLT time-profiles for skin penetration of light energy have not yet been investigated. Materials and methods: Sixty-two skin flaps overlaying rat’s gastrocnemius muscles were harvested and immediately irradiated with LLLT devices. Irradiation was performed either with a 810 nm, 200mW continuous wave laser, or with a 904 nm, 60mW superpulsed laser, and the amount of penetrating light energy was measured by an optical power meter and registered at seven time points (range, 1–150 sec). Results: With the continuous wave 810nm laser probe in skin contact, the amount of penetrating light energy was stable at *20% (SEM – 0.6) of the initial optical output during 150 sec irradiation. However, irradiation with the superpulsed 904 nm, 60mW laser showed a linear increase in penetrating energy from 38% (SEM – 1.4) to 58% (SEM – 3.5) during 150 sec of exposure. The skin penetration abilities were significantly different ( p < 0.01) between the two lasers at all measured time points. Conclusions: LLLT irradiation through rat skin leaves sufficient subdermal light energy to influence pathological processes and tissue repair. The finding that superpulsed 904nm LLLT light energy penetrates 2–3 easier through the rat skin barrier than 810nm continuous wave LLLT, corresponds well with results of LLLT dose analyses in systematic reviews of LLLT in musculoskeletal disorders. This may explain why the differentiation between these laser types has been needed in the clinical dosage recommendations of World Association for Laser Therapy.en_US
dc.language.isoengeng
dc.publisherMary Ann Lieberteng
dc.relation.ispartof<a href="http://hdl.handle.net/1956/7461" target="blank">Biophysical and biological effects from infrared Low-Level-Laser-Therapy</a>eng
dc.titleSkin Penetration Time-Profiles for Continuous 810nm and Superpulsed 904nm Lasers in a Rat Modelen_US
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright Mary Ann Liebert, Inc.
dc.identifier.doihttps://doi.org/10.1089/pho.2012.3306
dc.identifier.cristin981708
dc.source.journalPhotomedicine and Laser Surgery
dc.source.4030
dc.source.1412
dc.source.pagenumber688-694


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