Now showing items 811-830 of 1183

    • Occult obstructive coronary artery disease is associated with prolonged cardiac troponin elevation following strenuous exercise 

      Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Peer reviewed; Journal article, 2019)
      Background: Sudden cardiac death among middle-aged recreational athletes is predominantly due to myocardial ischaemia. This study examined whether measuring cardiac troponin I and T (cTnI and cTnT) after strenuous exercise ...
    • One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects 

      Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even; Berge, Rolf Kristian; Madsen, Lise; Steen, Vidar Martin; Skrede, Silje (Peer reviewed; Journal article, 2019-05)
      Background: Antipsychotic drugs can negatively affect the metabolic status of patients, with olanzapine as one of the most potent drugs. While patients are often medicated for long time periods, experiments in rats typically ...
    • Opptak av legemiddelanamnese ved innleggelse på sykehus 

      Brøndbo, Inga Aftret (Master thesis, 2011-05-20)
      Uheldige hendelser som følge av feil legemiddelbruk forårsaker årlig et betydelig antall dødsfall, invalidiserende skader og ekstra liggedøgn i sykehus. Halvparten av hendelsene kan forebygges. En stor andel feil skjer ved ...
    • Optic nerve constraints for carbon ion RT at CNAO ? Reporting and relating outcome to European and Japanese RBE 

      Dale, Jon Espen; Molinelli, Silvia; Vitolo, Viviana; Vischioni, Barbara; Bonora, Maria; Magro, Giuseppe; Pettersen, Helge Egil Seime; Mairani, Andrea; Hasegawa, Azusa; Dahl, Olav; Valvo, Francesca; Fossati, Piero (Peer reviewed; Journal article, 2019)
      Background and purpose: Until now, carbon ion RT (CIRT) dose constraints for the optic nerve (ON) have only been validated and reported in the NIRS RBE-weighted dose (DNIRS). The aim of this work is to improve CNAO’s ...
    • An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells 

      Davies, Richard Allan; Vogelsang, Petra; Jonsson, Roland; Appel, Silke (Peer reviewed; Journal article, 2016-09)
      Phosphoflow cytometry is increasingly being used as a tool for the discovery of biomarkers used in the treatment and monitoring of disease and therapy. The ability to measure numerous phospho-protein targets simultaneously ...
    • Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP 

      Gjerde, Kjersti; Lehmann, Sverre; Berge, Morten Eirik; Johansson, Ann-Katrin Gerd; Johansson, Anders (Peer reviewed; Journal article, 2015-12-27)
      The aim of this retrospective study was to evaluate the effect of individually adjusted custom-made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep ...
    • Oral microbiota in autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind; Siddiqui, Huma; Marthinussen, Michaela Cuida; Chen, Tsute; Jonsson, Roland; Oftedal, Bergithe Eikeland; Olsen, Ingar; Husebye, Eystein Sverre; Wolff, Anette Bøe (Peer reviewed; Journal article, 2018)
      Background: Autoimmune polyendocrine syndrome type-1 (APS-1) is a rare, childhood onset disease caused by mutations in the Autoimmune Regulator gene. The phenotypic expression is highly variable and includes disease ...
    • An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic n termini of transmembrane proteins and maintains golgi integrity 

      Aksnes, Henriette; Van Damme, Petra; Goris, Marianne; Starheim, Kristian K.; Marie, Michael Bruno Eric; Støve, Svein Isungset; Hoel, Camilla; Kalvik, Thomas Vikestad; Hole, Kristine; Glomnes, Nina; Furnes, Clemens; Ljostveit, Sonja; Ziegler, Mathias; Niere, Marc; Gevaert, Kris; Arnesen, Thomas (Peer reviewed; Journal article, 2015-02-26)
      N-terminal acetylation is a major and vital protein modification catalyzed by N-terminal acetyltransferases (NATs). NatF, or Nα-acetyltransferase 60 (Naa60), was recently identified as a NAT in multicellular eukaryotes. ...
    • Our genes, our selves: hereditary breast cancer and biological citizenship in Norway 

      Solbrække, Kari Nyheim; Søiland, Håvard; Lode, Kirsten; Gripsrud, Birgitta Haga (Peer reviewed; Journal article, 2017-03)
      In this paper we explore the rise of ‘the breast cancer gene’ as a field of medical, cultural and personal knowledge. We address its significance in the Norwegian public health care system in relation to so-called biological ...
    • Outcome after rewarming from accidental hypothermia by use of extracorporeal circulation 

      Svendsen, Øyvind Sverre; Grong, Ketil; Andersen, Knut Sverre; Husby, Paul (Peer reviewed; Journal article, 2017)
      Background: Accidental hypothermia with arrested circulation remains a condition associated with high mortality. In our institution, extracorporeal circulation (ECC) rewarming has been the cornerstone in treating such ...
    • OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation 

      Yang, Mingyi; Lin, Xiaolin; Segers, Filip; Suganthan, Rajikala; Hildrestrand, Gunn Annette; Rinholm, Johanne Egge; Aas, Per Arne; Sousa, Mirta; Holm, Sverre; Bolstad, Nils; Warren, David; Berge, Rolf Kristian; Johansen, Rune Forstrøm; Yndestad, Arne; Kristiansen, Elise; Klungland, Arne; Gomez, Luisa Fernanda Luna; Eide, Lars; Halvorsen, Bente; Aukrust, Pål; Bjørås, Magnar (Journal article; Peer reviewed, 2020)
      Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A−/−) develop fatty liver. RNA sequencing of male Oxr1A−/− liver indicates ...
    • Oxygen concentration in inhaled gas and nitric oxide concentration in exhaled gas. Is nitric oxide concentration in exhaled gas a useful marker for exposure to hyperoxia? 

      Caspersen, Cecilie (Doctoral thesis, 2014-04-10)
      Background: Exposure to partial pressures of oxygen (PO2) higher than 50 kPa may result in toxic effects on the lungs with reduced vital capacity, maximal expiratory flow rates and diffusion capacity. The risk of developing ...
    • p53 protein biosignatures in acute myeloid leukemia 

      Ånensen, Nina (Doctoral thesis, 2006-03-10)
      p53 is a tumor suppressor protein often regarded as the guardian of the genome. It is a highly connected protein involved in many signaling processes in the cell. The inactivation of p53 through genetic mutations in TP53 ...
    • Pain and pain tolerance in whiplash-associated disorders:A population-based study 

      Myrtveit, Solbjørg Makalani; Skogen, Jens Christoffer; Sivertsen, Børge; Steingrímsdóttir, Ólöf Anna; Stubhaug, Audun; Nielsen, Christopher Sivert (Peer reviewed; Journal article, 2015)
      Background: Pain is a cardinal symptom in individuals with whiplash-associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, ...
    • Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit 

      Tandberg, Bente Silnes; Flacking, Renée; Markestad, Trond Jacob; Grundt, Hege; Moen, Atle (Peer reviewed; Journal article, 2019-11-05)
      Background Studies of parents’ psychological well-being in single-family rooms in neonatal intensive care units have shown conflicting results. Aims To compare emotional distress in the form of depression, anxiety, stress ...
    • Parental anxiety related to referral of childhood heart murmur; an observational/interventional study 

      Bårdsen, Tonje; Sørbye, Mari Hoven; Trønnes, Håvard; Greve, Gottfried; Berg, Ansgar (Peer reviewed; Journal article, 2015-11-21)
      Background: Detection of a heart murmur in healthy children is common, but may generate anxiety among parents. Many parents believe a heart murmur is a sign of heart disease, although the majority of heart murmurs are ...
    • Parental involvement in decision-making about their child's health care at the hospital 

      Aarthun, Antje; Øymar, Knut; Akerjordet, Kristin (Peer reviewed; Journal article, 2018-07-30)
      Aim: To explore parents’ experiences on parental involvement in decision‐making about their child’s health care at the hospital and to identify how health professionals can improve parental involvement. Design: An explorative ...
    • Parental smoking and risk of childhood-onset type 1 diabetes 

      Magnus, Maria Christine; Tapia, German; Olsen, Sjurdur Frodi; Granström, Charlotta; Mårild, Karl Staffan; Ueland, Per Magne; Midttun, Øivind; Svensson, Jannet; Johannesen, Jesper; Skrivarhaug, Torild; Joner, Geir; Njølstad, Pål Rasmus; Størdal, Ketil; Stene, Lars Christian Mørch (Peer reviewed; Journal article, 2018-11)
      Background: A few prospective studies suggest an association between maternal smoking during pregnancy and lower risk of type 1 diabetes. However, the role of unmeasured confounding and misclassification remains unclear. ...
    • Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample 

      Johannessen, Tor Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Høyland, Anne Lise; Strohmaier, Jana; Heiberg, Arvid; Rietschel, Marcella; Djurovic, Srdjan; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2017-05-18)
      Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ...