Browsing Department of Clinical Science by Title
Now showing items 273-292 of 2605
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Bruk av inhalasjonsmedisiner hos pasienter i hjemmesykepleien
(Master thesis, 2021-05-20)Bakgrunn: Astma og kols er kroniske luftveissykdommer som først og fremst behandles med inhalasjonsmedisiner. Forekomsten av sykdommene er økende, spesielt kolsprevalens for eldre, ettersom at det blir flere eldre i ... -
Bruk av legemidler mot diabetes og depresjon i 2004 og 2009. Prevalens, sambruk, og risiko
(Master thesis, 2012-11-12)Farmakoepidemiologi er læren om legemiddelbruk i samfunnet. Ved hjelp av statistikk kan vi se nærmere på hvordan legemidler brukes av befolkningen og om det finnes et mønster i denne bruken. Diabetes og depresjon er begge ... -
Bruk av psykofarmaka ved syke- og aldershjem i Stavanger kommune - kan undervisning av ansatte bidra til mer hensiktsmessig forskrivning?
(Master thesis, 2022-05-20)Bakgrunn: I løpet av de neste ti årene vil befolkningen for første gang bestå av flere eldre enn yngre. Selv om legemiddelbehandling er en viktig årsak til at mennesker lever lenger, er eldre særlig utsatt for legemiddelrelaterte ... -
Bruken av antidiabetika i Norge for perioden 2004-2010. En reseptregisterstudie
(Master thesis, 2011-05-20)For å etablere gode rutiner for behandling av diabetes finnes det i dag kliniske retningslinjer. Kjernen i disse er først å benytte seg av veldokumenterte billige alternativer fremfor nye, dyrere og mindre dokumenterte ... -
Burden and characteristics of the comorbidity tuberculosis - diabetes in Europe : TBnet prevalence survey and case-control study
(Peer reviewed; Journal article, 2019-01)Background: The growing burden of diabetes mellitus (DM) is posing a threat to global tuberculosis (TB) control. DM triples the risk of developing TB, modifies the presenting features of pulmonary TB, and worsens TB treatment ... -
Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study
(Peer reviewed; Journal article, 2017-03-11)Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ... -
Burden of treatment in patients with chronic heart failure – A cross-sectional study
(Journal article; Peer reviewed, 2021)Background Patients with heart failure (HF) must manage both a demanding treatment regimen and self-care, which may lead to a burden of treatment. The purpose of this study was to assess the levels of burdens from treatment ... -
CA-125 levels are predictive of survival in low-grade serous ovarian cancer—A multicenter analysis
(Journal article; Peer reviewed, 2022-04-13)Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a ... -
Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections
(Journal article; Peer reviewed, 2023)Developing an effective therapy to overcome carbapenemase-positive Klebsiella pneumoniae (CPKp) is an important therapeutic challenge that must be addressed urgently. Here, we explored a Ca-EDTA combination with aztreonam ... -
CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation
(Journal article; Peer reviewed, 2023)Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding CaV1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and CaV1.3 ... -
Cadmium, lead and mercury in Norwegian obese patients before and 12 months after bariatric surgery
(Peer reviewed; Journal article, 2019)Purpose Previous studies have suggested a role for the toxic elements lead (Pb), mercury (Hg) and cadmium (Cd) in the development of insulin resistance and hypertension. Increased blood Pb levels have been reported after ... -
Calcium Channel Blockers and the Risk of Exacerbation in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Study of 48,488 Outpatients
(Journal article; Peer reviewed, 2023)Patients with chronic obstructive pulmonary disease (COPD) are prone to developing arterial hypertension, and many patients are treated with the calcium channel blocker amlodipine. However, it remains unclear whether using ... -
Calprotectin (S100A8/A9) and S100A12 in inflammatory arthritis : clinical and epidemiological studies of rheumatoid and psoriatic arthritis
(Doctoral thesis, 2007-12-14)Rheumatoid- and psoriatic arthritis (RA and PsA) are the two most prevalent inflammatory joint diseases in Caucasian. Different biomarkers in peripheral blood may contribute in the diagnostic and prognostic process, as ... -
Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis
(Peer reviewed; Journal article, 2017-01-12)Background: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is ... -
Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods
(Journal article; Peer reviewed, 2023)Calprotectin (S100A8/S100A9, MRP8/MRP14) is a major leukocyte protein found to be more sensitive than C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) as a marker of inflammation in patients with rheumatoid ... -
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
(Peer reviewed; Journal article, 2009-11-13)Background: An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro. The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, ... -
Can spirometric norms be set using pre- or post- bronchodilator test results in older people?
(Peer reviewed; Journal article, 2012-11-16)Background: Chronic Obstructive Pulmonary Disease (COPD) is defined by post-bronchodilator spirometry. Data on “normal values” come predominantly from pre-bronchodilator spirometry. The effects of this on diagnosis are ... -
Can The Use of Electronic Journal Systems Replace Human Intervention By The Medicine Reconciliation Process?
(Master thesis, 2016-05-20)Can the use of electronic journal systems replace human intervention by the medicine reconciliation process? By André Luong Keywords: Medicine/medication reconciliation, electronic journal systems/records, pharmacist ... -
Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital
(Peer reviewed; Journal article, 2019)Background: Worldwide, a large proportion of neonates are prescribed antibiotics without having infections leading to increased antimicrobial resistance, disturbance of the evolving microbiota, and increasing the risk of ... -
Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers
(Journal article; Peer reviewed, 2021)Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ...