Browsing Department of Clinical Science by Title
Now showing items 293-312 of 2573
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Candidate markers for stratification and classification in rheumatoid arthritis
(Peer reviewed; Journal article, 2019-07-05)Rheumatoid arthritis (RA) is a chronic autoimmune, inflammatory disease, characterized by synovitis in small- and medium-sized joints and, if not treated early and efficiently, joint damage, and destruction. RA is a ... -
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
(Journal article; Peer reviewed, 2020)The complex effects of plant cannabinoids on human physiology is not yet fully understood, but include a wide spectrum of effects on immune modulation. The immune system and its inflammatory effector pathways are recently ... -
The Capacity of Long-Term In Vitro Proliferation of Acute Myeloid Leukemia Cells Supported Only by Exogenous Cytokines Is Associated with a Patient Subset with Adverse Outcome
(Peer reviewed; Journal article, 2019-01-10)Acute myeloid leukemia (AML) is an aggressive malignancy, which is highly heterogeneous with regard to chemosensitivity and biological features. The AML cell population is organized in a hierarchy that is reflected in the ... -
Carbamylation of immunoglobulin abrogates activation of the classical complement pathway
(Peer reviewed; Journal article, 2014-11)Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory ... -
Carbapenem-Resistant Enterobacteriaceae—Implications for Treating Acute Leukemias, a Subgroup of Hematological Malignancies
(Journal article; Peer reviewed, 2021)Acute leukemias (AL) are a group of aggressive malignant diseases associated with a high degree of morbidity and mortality. Patients with AL are highly susceptible to infectious diseases due to the disease itself, factors ... -
Cardiac adaptation to hypertension in adult female Dahl salt-sensitive rats is dependent on ovarian function, but loss of ovarian function does not predict early maladaptation
(Peer reviewed; Journal article, 2018-02-08)Aim of study was to examine experimentally the adult female hypertensive heart in order to determine the role of ovary function in the response of the heart to salt‐dependent hypertension. Dahl salt‐sensitive rats, age 12 ... -
Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry
(Journal article; Peer reviewed, 2020)Objectives The Norwegian Cardiac Arrest Registry (NorCAR) was established in 2013 when cardiac arrest became a mandatory reportable condition. The aim of this cohort study is to describe how the world’s first mandatory, ... -
Cardiac Function and Early Risk Markers for Cardiovascular Disease in Children and Young Adults Surviving Severe Childhood Disease
(Doctoral thesis, 2023-11-03)Sammendrag på norsk Bakgrunn Prosessene som ligger bak utvikling av hjerte-kar sykdom starter tidlig i livet og er avhengig av antall risikofaktorer og debuttidspunkt av disse. Noen grupper er mer utsatt for hjerte-kar ... -
Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Peer reviewed; Journal article, 2018-03)Background: Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively ... -
Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Peer reviewed; Journal article, 2018-03)Background Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. ... -
Cardiac morphology in neonates with fetal growth restriction
(Journal article; Peer reviewed, 2023)Objective: Assess effects of fetal growth restriction (FGR) on cardiac modelling in premature and term neonates. Study design: Prospective echocardiographic study of a cohort of FGR neonates (n = 21) and controls (n = 41) ... -
Cardiac organ damage in systemic hypertension: Impact of gender, etiology, and comorbidities
(Doctoral thesis, 2024-03-15)Bakgrunn: Ukontrollert systemisk hypertensjon fører til økt risiko for kardiovaskulær sykdom og død både ved essensiell og sekundær hypertensjon. Den økte risikoen skyldes i stor grad utvikling av strukturelle og funksjonelle ... -
Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: a nationwide registry study
(Journal article; Peer reviewed, 2023) -
Cardiac Resynchronization Therapy (CRT): Patient Selection and Guideline Adherence : An Analysis of CRT Practice in Europe Based on the European Society of Cardiology CRT Survey II with 11088 patients in 42 countries.
(Doctoral thesis, 2020-09-04)Background/Aims Cardiac Resynchronization Therapy (CRT) reduces morbidity and mortality in patients with heart failure and electrical dyssynchrony. Recommendations for which patients should receive a CRT device are outlined ... -
Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value
(Journal article; Peer reviewed, 2020)Background Cardiac troponin (cTn) permits early rule‐out/rule‐in of patients admitted with possible non–ST‐segment–elevation myocardial infarction. In this study, we developed an admission and a 0/1 hour rule‐out/rule‐in ... -
Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)
(Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the ... -
Cardiometabolic risk factors differ among adolescents with obesity in three European countries - a cross sectional study
(Peer reviewed; Journal article, 2018-03)Aim: We aimed to compare modifiable cardiometabolic risk factors among treatment‐seeking adolescents with obesity in Italy, Germany and Norway. Methods: This retrospective, registry‐based, cross‐sectional cohort study ... -
Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats
(Journal article; Peer reviewed, 2023)Intrauterine hypoxia in newborns leads to a multifaceted array of alterations that exert a detrimental impact on the cardiovascular system. The aim of this research was to assess the cardioprotective effects of modulators ... -
Cardiotoxicity of Doxorubicin. A Study of Methods and Protective Interventions in Rat Models
(Doctoral thesis, 2015-03-13)Introduction: The clinical use of anthracyclines, like doxorubicin, is a double-edged sword. On one side, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases. On the other side; ... -
Cardiovascular organ damage in relation to hypertension status in patients with ankylosing spondylitis
(Journal article; Peer reviewed, 2023)Purpose Hypertension is a major cardiovascular (CV) risk factor in ankylosing spondylitis (AS) patients. Less is known about the prevalence of CV organ damage in relation to hypertension status in AS patients. Materials ...