Blar i Department of Clinical Science på tidsskrift "PLoS ONE"
Viser treff 41-52 av 52
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Relationship between Orthostatic Hypotension and White Matter Hyperintensity Load in Older Patients with Mild Dementia
(Peer reviewed; Journal article, 2012-12-19)Background/Objectives: White matter hyperintensities (WMH) in magnetic resonance imaging (MRI) scans of the brain, and orthostatic hypotension (OH) are both common in older people. We tested the hypothesis that OH is ... -
The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
(Peer reviewed; Journal article, 2019-10-24)Introduction: Exacerbations are major contributors to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD), and respiratory bacterial and viral infections are an important trigger. However, ... -
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice
(Peer reviewed; Journal article, 2014-05-19)Fish consumption is considered health beneficial as it decreases cardiovascular disease (CVD)-risk through effects on plasma lipids and inflammation. We investigated a salmon protein hydrolysate (SPH) that is hypothesized ... -
Sarcopenia in patients with hip fracture: A multicenter cross-sectional study
(Peer reviewed; Journal article, 2017-09-13)Background: Sarcopenia is prevalent in older persons and is a risk factor for falls, fractures, and mortality. The aim of this study was to determine a) the feasibility of determining sarcopenia in patients with acute hip ... -
Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats
(Peer reviewed; Journal article, 2019-12-05)Introduction: Peroxisome proliferator-activated receptors (PPARs) have been suggested to be involved in the regulation of one-carbon metabolism. Previously we have reported effects on plasma concentrations of metabolites ... -
Soluble Markers of the Toll-Like Receptor 4 Pathway Differentiate between Active and Latent Tuberculosis and Are Associated with Treatment Responses
(Peer reviewed; Journal article, 2013-07-16)Background. Biomarkers to differentiate between active tuberculosis (TB) and latent TB infection (LTBI) and to monitor treatment responses are requested to complement TB diagnostics and control, particularly in patients ... -
Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients
(Peer reviewed; Journal article, 2019-09-17)Background: Exacerbations of chronic obstructive pulmonary disease (COPD) are debilitating events and spur disease progression. Infectious causes are frequent; however, it is unknown to what extent exacerbations are caused ... -
Stathmin Protein Level, a Potential Predictive Marker for Taxane Treatment Response in Endometrial Cancer
(Peer reviewed; Journal article, 2014-02-25)Stathmin is a prognostic marker in many cancers, including endometrial cancer. Preclinical studies, predominantly in breast cancer, have suggested that stathmin may additionally be a predictive marker for response to ... -
Susceptibility to chronic mucus hypersecretion, a genome wide association study
(Peer reviewed; Journal article, 2014-04-08)Background: Chronic mucus hypersecretion (CMH) is associated with an increased frequency of respiratory infections, excess lung function decline, and increased hospitalisation and mortality rates in the general population. ... -
Switch in FOXA1 status associates with endometrial cancer progression
(Peer reviewed; Journal article, 2014-05-21)Background: The transcription factor Forkhead box A1 (FOXA1) is suggested to be important in hormone dependent cancers, although with little data for endometrial cancer. We investigated expression levels of FOXA1 in primary ... -
Use of loop diuretics is associated with increased mortality in patients with suspected coronary artery disease, but without systolic heart failure or renal impairment: an observational study using propensity score matching
(Peer reviewed; Journal article, 2015-06-01)Background Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long ... -
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
(Peer reviewed; Journal article, 2018-08-24)Background: Lower vitamin D levels are found in people with schizophrenia and depressive disorders, and also associated with neuroimaging abnormalities such as reduced brain volume in both animals and humans. Reduced whole ...