Browsing Department of Clinical Science by Title
Now showing items 2331-2350 of 2522
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T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ
(Peer reviewed; Journal article, 2017-07)Next generation sequencing of T and B cell receptors is emerging as a valuable and effective method to diagnose and monitor hematopoietic malignancies. So far, this approach has not been fully explored in regard to autoimmune ... -
T Cell Responses and Regulation and the Impact of In Vitro IL-10 and TGF-beta Modulation During Treatment of Active Tuberculosis
(Peer reviewed; Journal article, 2017-02)Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ... -
Tablettknusing i eldreomsorgen, sett fra et legemiddelteknologisk perspektiv
(Master thesis, 2011-05-19)Bakgrunn: Vi blir stadig eldre og med økende alder følger også økt morbiditet og dermed også medisinbruk. Mange eldre bor i omsorgsboliger og får tildelt medisiner av helsepersonell. Ofte kan det av ulike grunner være behov ... -
Tailoring NIV by dynamic laryngoscopy in a child with spinal muscular atrophy type I
(Journal article; Peer reviewed, 2021)Dynamic laryngoscopy during noninvasive (NIV) respiratory therapy is feasible and may facilitate optimal and individualized treatment in patients with chronic respiratory failure, also in children. -
TAKROLIMUS -Farmakokinetikk i tidlig fase etter levertransplantasjon
(Master thesis, 2009-05-20)Takrolimus er del av standard immunsuppresjon og vedlikeholdsdoseringsregimet etter levertransplantasjon. Det har et smalt terapeutisk vindu, og monitorers derfor etter bunnkonsentrasjonsmålinger. Intra- og interindividuelle ... -
TAM-reseptoruttrykk i labiale spyttkjertler hos pasienter med primært Sjögrens syndrom
(Master thesis, 2023-05-22)Hensikt: Studien sammenlignet TAM-reseptoruttrykk i labiale spyttkjertler mellom pasienter med primært Sjögrens syndrom og kontroller med sicca symptomer for å identifisere potensiell svekkelse av apoptotisk cellefjerning ... -
Tamoxifen in the treatment of luminal breast cancer. Implications of active metabolites on gene expression, side effects and clinical outcome
(Doctoral thesis, 2019-02-21)Estrogen is a driver for the development and progression of luminal breast cancer, and up to 80% of all breast cancers diagnosed belong to the luminal subtype. The estrogenic effect on breast tumors can be reduced by the ... -
Taxonomic diversity and abundance of enchytraeids (Annelida, Clitellata, Enchytraeida) in the Northern Palaearctic. 1. Asian part
(Journal article; Peer reviewed, 2024)Background: Enchytraeids, or potworms, are tiny oligochaetes that are distributed worldwide in many terrestrial, freshwater and marine ecosystems. Despite their key role in the functioning of ecosystems, the diversity and ... -
Teaching geriatric medicine through gamification: a tool for enhancing postgraduate education in geriatric medicine
(Journal article; Peer reviewed, 2022)Background Polypharmacy is becoming increasingly common and all doctors must be prepared to manage it competently. Aims The aim of this project is to evaluate the feasibility and use of a novel gamification-based ... -
Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway
(Peer reviewed; Journal article, 2016-10-04)Background: Beta-haemolytic streptococci are important contributors to the global burden of osteoarticular infections (OAI). Knowledge on the disease traits specific for streptococcal OAI, however, remains scarce. We wished ... -
Tentative longterm effects of a noradrenergic antidepressant; affecting the number of glucose transporters
(Master thesis, 2008-06-01)Major depressive disorder is an affective disorder affecting millions of people worldwide. Only in Europe at least 21 million are thought to be affected. Several theories have been developed during the years trying to ... -
Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty
(Peer reviewed; Journal article, 2020)Context: Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development ... -
Tetradecylthioacetic Acid Increases Hepatic Mitochondrial b-Oxidation and Alters Fatty Acid Composition in a Mouse Model of Chronic Inflammation
(Peer reviewed; Journal article, 2011-04-09)The administration of tetradecylthioacetic acid (TTA), a hypolipidemic and anti-inflammatory modified bioactive fatty acid, has in several experiments based on high fat diets been shown to improve lipid transport and ... -
Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress
(Peer reviewed; Journal article, 2011-10-25)Background: Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells in vitro and in vivo. The mechanisms behind the observed ... -
Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice
(Peer reviewed; Journal article, 2016-02-05)Background: Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condition ... -
Thawing plateau time indicating the duration of phase transition from ice to water is the strongest predictor for long-term durable pulmonary vein isolation after cryoballoon ablation for atrial fibrillation—Data from the index and repeat procedures
(Journal article; Peer reviewed, 2023)Introduction: This study aimed to clarify the relationship between the durability of pulmonary vein (PV) isolation and the time of phase transition from ice to water indicated by thawing plateau time in a cryoballoon ... -
The Effect of Krill Oil and Krill Hydrolysate Protein on Fat Storage and Metabolic health in Male Wistar Rats
(Master thesis, 2022-06-03) -
The effect of phytosubstances and plant-derived synthetic analogs on acute myeloid leukemia cells
(Master thesis, 2021-05-20) -
The regulation of tyrosine hydroxylase by dopamine and selected binding partners
(Master thesis, 2022-05-20)Tyrosine hydroxylase (TH) catalyses the rate limiting step in the metabolic pathway of dopamine (DA) synthesis and is therefore important in physiological functions such as motor control, cognitive function, and the brain ...