Browsing Department of Clinical Science by Author "Haanshuus, Christel Gill"
Now showing items 1-16 of 16
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Assessment of malaria real-time PCR methods and application with focus on lowlevel parasitaemia
Haanshuus, Christel Gill; Mørch, Kristine; Blomberg, Bjørn; Strøm, Gro Elizabeth Ann; Langeland, Nina; Hanevik, Kurt; Mohn, Stein Christian (Peer reviewed; Journal article, 2019-07-05)In epidemiological surveys and surveillance the application of molecular tools is essential in detecting submicroscopic malaria. A genus-specific conventional cytochrome b (cytb) PCR has shown high sensitivity in field ... -
Challenges in diagnosing paediatric malaria in Dar es Salaam, Tanzania
Strøm, Gro Elizabeth Ann; Haanshuus, Christel Gill; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Peer reviewed; Journal article, 2013-07-03)Background: Malaria is a major cause of paediatric morbidity and mortality. As no clinical features clearly differentiate malaria from other febrile illnesses, and malaria diagnosis is challenged by often lacking laboratory ... -
Challenges in diagnosing pediatric malaria in Dar es Salaam, Tanzania
Strøm, Gro Elizabeth Ann; Haanshuus, Christel Gill; Moyo, Sabrina John; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Conference poster, 2012-10-15) -
Clinical features and risk factors for death in acute undifferentiated fever: A prospective observational study in rural community hospitals in six states of India
Mørch, Kristine; Manoharan, Anand; Chandy, Sara; Singh, Ashita; Kuriakose, Cijoy; Patil, Suvarna; Henry, Anil; Chacko, Novin; Alvarez-Uria, Gerardo; Nesaraj, Joel; Blomberg, Bjørn; Kurian, Siby; Haanshuus, Christel Gill; Antony, George; Langeland, Nina; Mathai, Dilip (Journal article; Peer reviewed, 2023)Background Acute undifferentiated fever (AUF) ranges from self-limiting illness to life-threatening infections, such as sepsis, malaria, dengue, leptospirosis and rickettsioses. Similar clinical presentation challenges ... -
Detection of remaining Plasmodium DNA and gametocytes during follow up after curative malaria treatment among returned travellers in Norway
Haanshuus, Christel Gill; Mørch, Kristine (Journal article; Peer reviewed, 2020)Background PCR can be positive weeks after effective malaria treatment, potentially leading to over diagnose of recrudescence and re-infections. The DNA detected by PCR post-treatment might stem from residuals of destroyed ... -
Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country
Dyrhol-Riise, Anne Ma; Gran, Gerd; Wentzel-Larsen, Tore; Blomberg, Bjørn; Haanshuus, Christel Gill; Mørkve, Odd (Peer reviewed; Journal article, 2010-03-08)Background Interferon-gamma (IFN-γ) Release Assays (IGRA) are more specific than the tuberculosis skin test (TST) in the diagnosis of latent tuberculosis (TB) infection (LTBI). We present the performance of the QuantiFERON®-TB ... -
emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway
Kittang, Bård Reiakvam; Skrede, Steinar; Langeland, Nina; Haanshuus, Christel Gill; Mylvaganam, Haima (Peer reviewed; Journal article, 2010-11-20)In order to investigate molecular characteristics of beta-hemolytic streptococcal isolates from western Norway, we analysed the entire emm gene sequences, obtained superantigen gene profiles and determined the prevalence ... -
Malaria prevalence among patients with acute undifferentiated fever in secondary hospitals in India
Haanshuus, Christel Gill; Vivek, Rosario; Xena, Deepika; Chandy, Sara; Mathai, Dilip; Manoharan, Anand; Langeland, Nina; Blomberg, Bjørn; Mørch, Kristine (Conference poster, 2014-09-22) -
Malaria prevalence and performance of diagnostic tests among patients hospitalized with acute undifferentiated fever in Zanzibar
Onken, Annette; Haanshuus, Christel Gill; Miraji, Mohammed Khamis; Marijani, Msafiri; Kibwana, Kibwana Omar; Abeid, Khamis Ali; Mørch, Kristine; Reimers, Marianne; Langeland, Nina; Müller, Fredrik; Jenum, Pål; Blomberg, Bjørn (Journal article; Peer reviewed, 2022-02-19)Background: Control efforts in Zanzibar reduced the burden of malaria substantially from 2000 to 2015, but re-emergence of falciparum malaria has been observed lately. This study evaluated the prevalence of malaria and ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
PCR based Malaria diagnostics : – Method development and application
Haanshuus, Christel Gill (Doctoral thesis, 2019-11-12)Background Almost half of the world’s population is at risk of malaria. Malaria is a parasitic vector borne disease spread by infected female Anopheles mosquitos. The protozoan parasite belongs to the genus Plasmodium ... -
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Berg, Åse; Patel, Sam; Tellevik, Marit Gjerde; Haanshuus, Christel Gill; Dalen, Ingvild; Otterdal, Kari; Ueland, Thor; Moyo, Sabrina John; Aukrust, Pål; Langeland, Nina (Journal article; Peer reviewed, 2020)Purpose When considering malaria disease severity, estimation of parasitemia in erythrocytes is important, but sometimes misleading, since the infected erythrocytes may be sequestered in peripheral capillaries. In African ... -
Serological profile among patients with malaria in secondary community hospitals in India - a multicenter cross sectional study
Mørch, Kristine; Vivek, Rosario; Xena, Depeeka; Chandy, Sara; Manoharan, Anand; Haanshuus, Christel Gill; Langeland, Nina; Blomberg, Bjørn; Mathai, Dilip (Conference poster, 2014-09-22) -
Single amplification PCR targeting mitochondrial genome more sensitive in diagnosing malaria than nested 18S PCR among returned travelers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Conference poster, 2012-10-15) -
Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria
Otterdal, Kari; Berg, Åse; Michelsen, Annika; Patel, Sam; Tellevik, Marit Gjerde; Haanshuus, Christel Gill; Fevang, Børre; Aukrust, Pål; Langeland, Nina; Ueland, Thor (Peer reviewed; Journal article, 2018-12-18)BACKGROUND: The immune response during P. falciparum infection is a two-edged sword, involving dysregulation of the inflammatory responses with several types of immune cells participating. Here we examined T-cell, ...