Blar i Department of Clinical Science på forfatter "Hagland, Hanne Røland"
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Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish
Alhourani, Abdelnour; Førde, Jan-Lukas; Nasrollahzadeh, Mojdeh; Eichacker, Lutz Andreas; Herfindal, Lars; Hagland, Hanne Røland (Journal article; Peer reviewed, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation
Førde, Jan-Lukas; Alhourani, Abdelnour; Carey, Tian; Arbab, Adrees; Fladmark, Kari Espolin; Skrede, Silje; Mollnes, Tom Eirik; Herfindal, Lars; Hagland, Hanne Røland (Journal article; Peer reviewed, 2024)Graphene, a material composed of a two-dimensional lattice of carbon atoms, has due to its many unique properties a wide array of potential applications in the biomedical field. One of the most common production methods ... -
Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide
Alhourani, Abdelnour; Førde, Jan-Lukas; Eichacker, Lutz Andreas; Herfindal, Lars; Hagland, Hanne Røland (Journal article; Peer reviewed, 2021)Graphene-based drug carriers provide a promising addition to current cancer drug delivery options. Increased accessibility of high-quality graphene made by plasma-enhanced chemical vapor deposition (PE-CVD) makes it an ...