Blar i Department of Clinical Science på tidsskrift "Communications Biology"
Viser treff 1-3 av 3
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Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
(Peer reviewed; Journal article, 2018-10-08)Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the ... -
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
(Journal article; Peer reviewed, 2021)T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T ... -
A radiogenomics application for prognostic profiling of endometrial cancer
(Journal article; Peer reviewed, 2021)Prognostication is critical for accurate diagnosis and tailored treatment in endometrial cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance imaging (MRI, n = 487 patients) with histologic-, ...