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dc.contributor.authorMahande, Michael Johnsonen_US
dc.contributor.authorDaltveit, Anne Kjerstien_US
dc.contributor.authorMmbaga, Blandina T.en_US
dc.contributor.authorObure, Josephen_US
dc.contributor.authorMasenga, Gilearden_US
dc.contributor.authorManongi, Rachelen_US
dc.contributor.authorLie, Rolv Terjeen_US
dc.PublishedBMC Pregnancy and Childbirth 13(1):166eng
dc.description.abstractBackground Perinatal mortality is known to be high in Sub-Saharan Africa. Some women may carry a particularly high risk which would be reflected in a high recurrence risk. We aim to estimate the recurrence risk of perinatal death using data from a hospital in Northern Tanzania. Methods We constructed a cohort study using data from the hospital based KCMC Medical Birth Registry. Women who delivered a singleton for the first time at the hospital between 2000 and 2008 were followed in the registry for subsequent deliveries up to 2010 and 3,909 women were identified with at least one more delivery within the follow-up period. Recurrence risk of perinatal death was estimated in multivariate models analysis while adjusting for confounders and accounting for correlation between births from the same mother. Results The recurrence risk of perinatal death for women who had lost a previous baby was 9.1%. This amounted to a relative risk of 3.2 (95% CI: 2.2 - 4.7) compared to the much lower risk of 2.8% for women who had had a surviving baby. Recurrence contributed 21.2% (31/146) of perinatal deaths in subsequent pregnancies. Preeclampsia, placental abruption, placenta previa, induced labor, preterm delivery and low birth weight in a previous delivery with a surviving baby were also associated with increased perinatal mortality in the next pregnancy. Conclusions Some women in Tanzanian who suffer a perinatal loss in one pregnancy are at a particularly high risk of also losing the baby of a subsequent pregnancy. Strategies of perinatal death prevention that target pregnant women who are particularly vulnerable or already have experienced a perinatal loss should be considered in future research.en_US
dc.publisherBioMed Central Ltd.eng
dc.relation.ispartof<a href="" target="blank">Recurrence of Perinatal Death, Preterm Birth and Preeclampsia in Northern Tanzania: A Registry Based Study</a>eng
dc.rightsAttribution CC BYeng
dc.subjectPerinatal mortalityeng
dc.subjectPerinatal deatheng
dc.subjectRisk factorseng
dc.subjectContinuation rateeng
dc.titleRecurrence of perinatal death in Northern Tanzania: a registry based cohort studyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2013 Mahande et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.holderMichael J Mahande et al.; licensee BioMed Central Ltd.

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