• UGT1A4 og UGT2B15 enkeltnukleotidpolymorfismer. Etablering av real time PCR metoder og betydning for tamoxifen metabolisme 

      Ness, Ole-Johan (Master thesis, 2008-06-02)
      Brystkreft er den vanligste kreftformen blant kvinner i Norge og adjuvant tamoxifenbehandling er vist å øke tilbakefallsfri og total overlevelse. Den interinidividuelle varaiasjonen i effekt og bivirkninger av tamoxifen ...
    • Ultraprosessert mat burde være et kostråd: JA 

      Dankel, Simon N; Molin, Marianne; Bere, Elling Tufte (Journal article, 2023)
    • Ultrasonography of major salivary glands in primary and juvenile Sjögren’s syndrome 

      Hammenfors, Daniel S. (Doctoral thesis, 2019-06-07)
      Background: Primary Sjögrens’s syndrome (pSS) is a systemic autoimmune disease, mainly affecting the salivary and lacrimal glands. Primary SS can also affect the younger population and when it does, the denomination is ...
    • Ultrasound in Crohn’s Disease - bowel wall characteristics and perfusion estimates using microbubbles 

      Nylund, Kim (Doctoral thesis, 2013-01-18)
      Crohn’s disease (CD) is a chronic inflammatory bowel disease which often presents early in life and sometimes can be debilitating. The patients need frequent diagnostic work-up to assess disease activity, location, extent ...
    • Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells 

      Bjånes, Tormod Karlsen; Kotopoulis, Spiros; Murvold, Elsa Thodesen; Kamceva, Tina; Gjertsen, Bjørn Tore; Gilja, Odd Helge; Schjøtt, Jan; Riedel, Bettina; McCormack, Emmet (Journal article; Peer reviewed, 2020)
      Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles ...
    • Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS) 

      Triebner, Kai; Bifulco, Ersilia; Barrera-Gómez, Jose; Basagaña, Xavier; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Garcia-Larsen, Vanessa; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren-Agirre, Nerea; Pin, Isabelle; Raherison, Chantal; Pereira-Vega, Antonio; Schlünssen, Vivi; Valentin, Antonia; Hustad, Steinar; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2021)
      Background Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites ...
    • Understanding fatigue in Sjögren’s Syndrome: Outcome measures, biomarkers and possible interventions 

      Mæland, Elisabeth; Miyamoto, Samira T.; Hammenfors, Daniel; Valim, Valeria; Jonsson, Malin Viktoria (Journal article; Peer reviewed, 2021)
      Sjögren’s syndrome (SS) is an autoimmune disease affecting the salivary and lacrimal glands. Symptoms range from dryness to severe extra-glandular disease involving manifestations in the skin, lungs, nervous system, and ...
    • Understanding the Effects of Antipsychotics on Appetite Control 

      Mukherjee, Sayani; Skrede, Silje; Milbank, Edward; Andriantsitohaina, Ramaroson; López, Miguel; Fernø, Johan (Journal article; Peer reviewed, 2021)
      Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so-called extrapyramidal side effects, and ...
    • Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center 

      Steiner, Sophie; Fehrer, Annick; Hoheisel, Friederike; Schoening, Simon; Aschenbrenner, Anna; Babel, Nina; Bellmann-Strobl, Judith; Finke, Carsten; Fluge, Øystein; Froehlich, Laura; Goebel, Andreas; Grande, Bettina; Haas, Johannes-Peter; Hohberger, Bettina; Jason, Leonard A.; Komaroff, Anthony L.; Lacerda, Eliana; Liebl, Max; Maier, Andrea; Mella, Olav; Nacul, Luis; Paul, Friedemann; Prusty, Bhupesh K.; Puta, Christian; Riemekasten, Gabriela; Ries, Wolfgang; Rowe, Peter C.; Sawitzki, Birgit; Shoenfeld, Yehuda; Schultze, Joachim L.; Seifert, Martina; Sepúlveda, Nuno; Sotzny, Franziska; Stein, Elisa; Stingl, Michael; Ufer, Friederike; Veauthier, Christian; Westermeier, Francisco; Wirth, Klaus; Wolfarth, Bernd; Zalewski, Pawel; Behrends, Uta; Scheibenbogen, Carmen (Journal article; Peer reviewed, 2023)
      Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase ...
    • Undersøke sammenhengen mellom jernstatus og jernabsorpsjon. Sammenligning av friske og pasienter med hemokromatose 

      Bø, Eirik Svandal (Master thesis, 2008-06-01)
      Jern er et essensielt spormetall som vi har ca 3-4 g av i kroppen. Jern inngår i flere proteiner, der hemoglobin er det viktigste. Jern er også delaktig i flere redoksreaksjoner i kroppen vår. Vi trenger daglig et tilskudd ...
    • Unexplained chronic liver disease in Ethiopia: a cross-sectional study 

      Orlien, Stian Magnus Staurung; Ismael, Nejib Yusuf; Ahmed, Tekabe Abdosh; Berhe, Nega; Lauritzen, Trine; Roald, Borghild; Goldin, Robert David; Stene-Johansen, Kathrine; Dyrhol-Riise, Anne Ma; Gundersen, Svein Gunnar; Morgan, Marsha Yvonne; Johannessen, Asgeir (Peer reviewed; Journal article, 2018-02-13)
      Background: Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence ...
    • Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation 

      Valeur, Jørgen (Doctoral thesis, 2010-10-08)
      Background: Self-reported food hypersensitivity remains unexplained in most cases. Abdominal symptoms, typically consistent with the irritable bowel syndrome (IBS), are common in patients with such unexplained, self-reported ...
    • Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients 

      Theorell, Jakob; Bileviciute-Ljungar, Indre; Tesi, Bianca; Schlums, Heinrich; Johnsgaard, Mette Sophie; Asadi-Azarbaijani, Babak; Strand, Elin Bolle; Bryceson, Yenan (Peer reviewed; Journal article, 2017-06-26)
      Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a debilitating disorder linked to diverse intracellular infections as well as physiological stress. Cytotoxic lymphocytes combat intracellular infections. ...
    • Unsupervised clustering of missense variants in HNF1A using multidimensional functional data aids clinical interpretation 

      Althari, Sara; Najmi, Laeya Abdoli; Bennett, Amanda J.; Aukrust, Ingvild; Rundle, Jana K.; Colclough, Kevin; Molnes, Janne; Kaci, Alba; Nawaz, Sameena; van der Lugt, Timme; Hassanali, Neelam; Mahajan, Anubha; Molven, Anders; Ellard, Sian; McCarthy, Mark I.; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Gloyn, Anna L. (Journal article; Peer reviewed, 2020-10-01)
      Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), ...
    • Update on primary sclerosing cholangitis 

      Karlsen, Tom Hemming; Boberg, Kirsten Muri (Peer reviewed; Journal article, 2013-09)
      Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ...
    • Updated total IgE reference intervals in Norwegian adults 

      Vinnes, Erik Wilhelm; Skarbø, Birthe Rochlenge Skarbø; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2023)
      Background It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ...
    • The urban-rural gradient in asthma: A population-based study in Northern Europe 

      Timm, Signe; Frydenberg, Morten; Janson, Christer; Campbell, Brittany; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Jõgi, Rain; Omenaas, Ernst; Sigsgaard, Torben; Svanes, Cecilie; Schlünssen, Vivi (Peer reviewed; Journal article, 2015-12-30)
      The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...
    • Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial 

      Borowczyk, Kamila; Piechocka, Justyna; Głowacki, Rafał; Dhar, Indu; Midttun, Øivind; Tell, Grethe S.; Ueland, Per Magne; Nygård, Ottar; Jakubowski, Hieronim (Peer reviewed; Journal article, 2018)
      Objectives: No individual homocysteine (Hcy) metabolite has been studied as a risk marker for coronary artery disease (CAD). Our objective was to examine Hcy‐thiolactone, a chemically reactive metabolite generated by ...
    • Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction 

      Streng, Koen W.; Hillege, Hans L.; ter Maaten, Jozine M.; van Veldhuisen, Dirk J.; Dickstein, Kenneth; Samani, Nilesh J.; Ng, Leong L.; Metra, Marco; Filippatos, Gerasimos S.; Ponikowski, Piotr; Zannad, Faiez; Anker, Stefan D.; van der Meer, Peter; Lang, Chim C.; Voors, Adriaan A.; Damman, Kevin (Journal article; Peer reviewed, 2023)
      Background Recent data suggest different causes of renal dysfunction between heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF). We therefore studied a wide range of urinary markers reflecting ...
    • The use of 16S rRNA targeted next generation sequencing in diagnostics of polymicrobial invasive infections 

      Dyrhovden, Ruben (Doctoral thesis, 2023-08-21)
      16S rRNA dypsekvensering muliggjør, som vist i flere vitenskapelige arbeider, en mer fullstendig karakterisering av komplekse bakterielle mikrobiota enn det som kan oppnås ved tradisjonelle, dyrkningsbaserte, mikrobiologiske ...