Blar i Department of Clinical Science på tittel
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Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
(Journal article; Peer reviewed, 2022)Several lines of evidence implicate immune abnormalities in the pathophysiology of severe mental disorders (SMD) and comorbid mental disorders. Here, we use the data from genome-wide association studies (GWAS) of autoimmune ... -
Immune regulatory mechanisms in endocrine autoimmune disorders
(Doctoral thesis, 2023-09-15)Ulike mekanismer eksisterer for at immunforsvaret skal lære å skille det som er eget fra det som er fremmed, også kjent som immunologisk toleranse. I noen tilfeller brytes denne toleransen, noe som kan føre til at enkelte ... -
Immune response to influenza after vaccination and infection
(Doctoral thesis, 2016-09-23)Influenza causes great human morbidity and mortality from annual epidemics and pandemics occurring at irregular intervals. The socioeconomic impact of influenza is significant with 5% of adults and 20% of children infected, ... -
Immune Responses in Acute and Convalescent Patients with Mild, Moderate and Severe Disease during the 2009 Influenza Pandemic in Norway
(Peer reviewed; Journal article, 2015-11-25)Increased understanding of immune responses influencing clinical severity during pandemic influenza infection is important for improved treatment and vaccine development. In this study we recruited 46 adult patients during ... -
The immunogenicity of intranasal adjuvanted pandemic avian influenza vaccine in murine model
(Master thesis, 2009-07-02)Influenza vaccination remains the primary method for the prevention of influenza and the severe complications related to the disease. Development of an intranasal vaccination strategy will not only prevent the disease but ... -
Immunoglobulin-storing histiocytosis: A case based systemic review
(Journal article; Peer reviewed, 2021)Crystal-storing histiocytosis (CSH) is a rare event in disorders associated with monoclonal gammopathy and is mostly associated with the accumulation of immunoglobulins (Igs) in the cytoplasm of histiocytes. In this article, ... -
Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer
(Journal article; Peer reviewed, 2021)Objective: Pre-operative immunohistochemical (IHC) biomarkers are not incorporated in endometrial cancer (EC) risk classification. We aim to investigate the added prognostic relevance of IHC biomarkers to the ESMO-ESGO-ESTRO ... -
Immunological aspects of acute myelogenous leukemia
(Doctoral thesis, 2007-02-23)Acute myelogenous leukemia (AML) is an aggressive malignancy characterized by accumulation of immature myeloid cells in the bone marrow. The overall disease-free survival is less than 50% even for the younger patients who ... -
The immunological dilemma: Cellular innate and adaptive immune response versus human acute myeloid leukemia
(Peer reviewed; Journal article, 2007)It is generally accepted that acute myelogenous leukemia (AML) patients are immunocompromized. On the other hand, antileukemic immune reactivity is important for the improved survival of AML patients treated with allogeneic ... -
Immunological heterogeneity of healthy peripheral blood stem cell donors - Effects of granulocyte colony-stimulating factor on inflammatory responses
(Peer reviewed; Journal article, 2018-09-22)Interleukin-6 (IL-6) contributes to the development of immune-mediated complications after allogeneic stem cell transplantation. However, systemic IL-6 levels also increase during granulocyte colony-stimulating factor ... -
Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
(Journal article; Peer reviewed, 2019)Changes in the immune system induced by tyrosine kinase inhibitors (TKI) have been shown to positively correlate with therapy responses in chronic myeloid leukemia (CML). However, only a few longitudinal studies exist and ... -
The immunology of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; what can the tonsils reveal. A literature review.
(Peer reviewed; Journal article, 2020)Objectives: Tonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. ... -
Immunomodulation induced by stem cell mobilization and harvesting in healthy donors: Increased systemic osteopontin levels after treatment with granulocyte colony-stimulating factor
(Peer reviewed; Journal article, 2016-07-19)Peripheral blood stem cells from healthy donors mobilized by granulocyte colony-stimulating factor (G-CSF) and harvested by leukapheresis are commonly used for allogeneic stem cell transplantation. The frequency of severe ... -
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
(Peer reviewed; Journal article, 2018-01-29)Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT1–7) many of which are also involved in immune processes. Dendritic cells (DCs) are crucial players in immune defense by bridging ... -
Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes
(Journal article; Peer reviewed, 2020)Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells. ... -
Immunophenotyping in post-giardiasis functional gastrointestinal disease and chronic fatigue syndrome
(Peer reviewed; Journal article, 2012-10-14)Background: A Giardia outbreak was associated with development of post-infectious functional gastrointestinal disorders (PI-FGID) and chronic fatigue syndrome (PI-CFS). Markers of immune dysfunction have given conflicting ... -
Immunoregulatory networks in healthy adult allogeneic stem cell donors : Studies of peripheral hematopoietic stem cell donors and their recipients
(Doctoral thesis, 2020-10-28)Final outcome after allogeneic peripheral blood stem cell transplantation (PBSCT) is influenced by the high degrees of variation in disease and comorbidities among recipients, as well as the pre-and post-transplant handling ... -
Impact of a Mobile Application for Tracking Nausea and Vomiting During Pregnancy (NVP) on NVP Symptoms, Quality of Life, and Decisional Conflict Regarding NVP Treatments: MinSafeStart Randomized Controlled Trial
(Journal article; Peer reviewed, 2022)Background: Pregnant women are active users of mobile apps for health purposes. These apps may improve self-management of health-related conditions. Up to 70% of pregnant women experience nausea and vomiting (NVP). Even ... -
Impact of a surgical safety checklist on safety culture, morbidity, and mortality. A stepped-wedge cluster randomised controlled trial
(Doctoral thesis, 2014-08-26)Introduction: The incidence of in-hospital adverse events is estimated to occur in approximately 1 out of 10 patients. Events happening during surgical procedures contribute up to 60%, and of these, more than half are ... -
Impact of aortic stiffness on myocardial ischaemia in non-obstructive coronary artery disease
(Peer reviewed; Journal article, 2019)Objective: High aortic stiffness may reduce myocardial perfusion pressure and contribute to development of myocardial ischaemia. Whether high aortic stiffness is associated with myocardial ischaemia in patients with stable ...