Blar i Department of Clinical Science på tittel
Viser treff 1161-1180 av 2293
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Indoor airborne microbiome, environmental and household determinants and respiratory health in Northern Europe
(Doctoral thesis, 2023-09-22)Bakgrunn: Overgangen fra utemiljø til bygde miljøer har redusert vår eksponering for mikrobielt mangfold. I dag tilbringer det moderne mennesket opptil 80% av tiden innendørs. Tidligere studier har vist at eksponering for ... -
Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study
(Peer reviewed; Journal article, 2018-11-01)Objectives To determine whether an association exists between delirium and length of time indwelling urine catheters (IUC) are used in octogenarian patients treated with surgical aortic valve treatment (SAVR) or transcatheter ... -
Infected Hip and Knee Arthroplasties in Rheumatoid Arthritis. A register-based study with focus on risk factors
(Doctoral thesis, 2014-09-05)Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease which primarily affects and damages synovial joints. Patients with RA will therefore often undergo joint replacement surgery. Infections after such ... -
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
(Journal article; Peer reviewed, 2023)A potential relationship between dysregulation of immune/inflammatory pathways and cognitive impairment has been suggested in severe mental illnesses (SMI), such as schizophrenia (SZ) and bipolar (BD) spectrum disorders. ... -
Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study
(Journal article; Peer reviewed, 2022)Our aim was to test sex-specific associations of circulating markers of inflammation with blood pressure (BP) and incident hypertension in midlife. Participants in the Hordaland Health study (n = 3280, 56% women, mean age ... -
Inflammatory biomarkers with focus on Calprotectin (S100A8/S100A9) and S100A12 (EN-RAGE) : method development and application in acute radiation proctitis and rheumatoid arthritis patients
(Doctoral thesis, 2007-02-02)Assessments of diseases are usually performed by a combination of clinical symptoms, signs and objective measurements. Biochemical markers of inflammation are important in evaluation of treatment of acute and chronic ... -
Inflammatory markers, the tryptophan-kynurenine pathway, and Vitamin B status after bariatric surgery
(Peer reviewed; Journal article, 2018-02-05)Objective: Obesity is associated with increased inflammation and insulin resistance. In conditions with chronic immune activation, low plasma vitamin B6-levels are described, as well as an increased kynurenine:tryptophan-ratio ... -
The influence of acute unloading on left ventricular strain and strain rate by speckle tracking echocardiography in a porcine model
(Peer reviewed; Journal article, 2016)Noninvasive measurements of myocardial strain and strain rate by speckle tracking echocardiography correlate to cardiac contractile state but also to load, which may weaken their value as indices of inotropy. In a porcine ... -
Influence of Age and Nutritional Status on the Performance of the Tuberculin Skin Test and QuantiFERON®-TB Gold In-Tube in Young Children Evaluated for Tuberculosis in Southern India.
(Peer reviewed; Journal article, 2014-10)Background: Reliable identification of Mycobacterium tuberculosis infection or tuberculosis (TB) disease in young children is vital to assure adequate preventive and curative treatment. The tuberculin skin test (TST) and ... -
Influence of Annular Dynamics and Material Behavior in Finite Element Analysis of Barlow’s Mitral Valve Disease
(Journal article; Peer reviewed, 2021)Barlow’s disease affects the entire mitral valve apparatus, by altering several of the fundamental mechanisms in the mitral valve which ensures unidirectional blood flow between the left atrium and the left ventricle. In ... -
The influence of immigrant background and parental education on overweight and obesity in 8-year-old children in Norway
(Journal article; Peer reviewed, 2023)Background Little is known about the prevalence of overweight/obesity and socio-economic position (SEP) in children with immigrant background in Scandinavia. The purpose of this study is to examine the prevalence of ... -
Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon
(Peer reviewed; Journal article, 2015-07)MDM2 is a key regulator of the p53 tumor suppressor protein and is overexpressed in many human cancers. Two single nucleotide polymorphisms (SNPs) located in the MDM2 intronic promoter (P2) have been found to exert biological ... -
Influence of obesity on left ventricular adaptation, grading and outcome in aortic valve stenosis
(Doctoral thesis, 2014-09-29)Background/Aim: Obesity is associated with hemodynamic changes characterized by volume overload adding to the progressive pressure overload induced by aortic valve stenosis (AS). This thesis investigated whether concomitant ... -
Influence of p53 isoform expression on survival in high-grade serous ovarian cancers
(Peer reviewed; Journal article, 2019-03-27)High-grade serous ovarian carcinoma (HGSOC) is characterised by alterations in the p53 pathway. The expression levels of p53 isoforms have been shown to be associated with patient survival in several cancers. This study ... -
The influence of region of interest width in fetal 2D-speckle tracking echocardiography late in pregnancy
(Journal article; Peer reviewed, 2021)Speckle tracking echocardiography is a promising method for assessment of myocardial function in fetal and neonatal hearts, but further studies are necessary to validate and optimize the settings for use in fetal cardiology. ... -
The influence of socio-demographic and clinical factors on sick leave and return to work after open-heart surgery: a nationwide registry-based cohort study
(Journal article; Peer reviewed, 2023)Aims: To estimate sick leave (SL) duration after first-time elective open-heart surgery and identify factors contributing to increased SL. Methods and results: A retrospective nationwide cohort study combined data from ... -
Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines
(Peer reviewed; Journal article, 2015-04-24)Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual influenza vaccination is recommended for groups at ... -
Influenza virus and related activity in the palatine tonsils after live attenuated influenza vaccination
(Master thesis, 2015-10-30)Influenza is a common infection in humans, with annual outbreaks. It can cause severe disease and have great socioeconomic impact. Children are more susceptible to infection than adults, especially when they have a naïve ... -
Inhibiting notch activity in breast cancer stem cells by glucose functionalized nanoparticles carrying γ-secretase inhibitors
(Peer reviewed; Journal article, 2016-05)Cancer stem cells (CSCs) are a challenge in cancer treatment due to their therapy resistance. We demonstrated that enhanced Notch signaling in breast cancer promotes self-renewal of CSCs that display high glycolytic activity ... -
Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis
(Peer reviewed; Journal article, 2016-08-11)Rheumatoid arthritis is characterised by synovial inflammation and proliferation of fibroblast-like synoviocytes. The induction of apoptosis has long been proposed as a target for proliferative autoimmune diseases, and has ...