• Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study 

      Husebø, Gunnar Reksten; Bakke, Per; Aanerud, Marianne; Hardie, Jon Andrew; Ueland, Thor; Grønseth, Rune; Persson, Louise Jeanette Pauline; Aukrust, Pål; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2014-10-03)
      Background: COPD exacerbations accelerate disease progression. Aims To examine if COPD characteristics and systemic inflammatory markers predict the risk for acute COPD exacerbation (AECOPD) frequency and duration. Methods: ...
    • Protected sampling is preferable in bronchoscopic studies of the airway microbiome 

      Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Tangedal, Solveig; Xue, Yaxin; Husebø, Gunnar; Svanes, Øistein; Lehmann, Sverre; Aardal, Marit Elisabeth; Hoang, Tuyen; Kalananthan, Tharmini; Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Aanerud, Marianne; Nordeide, Eli; Haaland, Ingvild; Jonassen, Inge; Bakke, Per S.; Eagan, Tomas Mikal (Journal article; Peer reviewed, 2017)
      The aim was to evaluate susceptibility of oropharyngeal contamination with various bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control subjects underwent bronchoscopy with ...
    • Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey 

      Voll-Aanerud, Marianne; Eagan, Tomas Mikal; Plana, Estel; Omenaas, Ernst; Bakke, Per; Svanes, Cecilie; Siroux, Valerie; Pin, Isabelle; Antó, Josep M.; Leynaert, Benedicte (Peer reviewed; Journal article, 2010-09-27)
      Background Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with HRQoL ...
    • The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease 

      van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per S.; Claas, Eric C.J.; Eagan, Tomas Mikal; Hiemstra, Pieter S.; Kroes, Aloys C.M.; de Vries, Jutte J.C. (Peer reviewed; Journal article, 2019-10-24)
      Introduction: Exacerbations are major contributors to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD), and respiratory bacterial and viral infections are an important trigger. However, ...
    • Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study 

      Husebø, Gunnar Reksten; Nielsen, Rune; Hardie, Jon Andrew; Bakke, Per S.; Lerner, Lorena; D'Alessandro-Gabazza, Corina; Gyuris, Jeno; Gabazza, Esteban; Aukrust, Pål; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2019)
      Background: COPD patients have an increased risk of developing lung cancer, but the underlying mechanisms are poorly understood. We aimed to identify risk factors for lung cancer in patients from the Bergen COPD Cohort ...
    • Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients 

      Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne; Persson, Louise Jeanette Pauline; Wiker, Harald G; Bakke, Per S.; Hiemstra, Pieter S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2019-09-17)
      Background: Exacerbations of chronic obstructive pulmonary disease (COPD) are debilitating events and spur disease progression. Infectious causes are frequent; however, it is unknown to what extent exacerbations are caused ...
    • TNF-α is associated with loss of lean body mass only in already cachectic COPD patients 

      Eagan, Tomas Mikal; Gabazza, Esteban C.; D’Alessandro-Gabazza, Corina; Gil-Bernabe, Paloma; Aoki, Shinya; Hardie, Jon Andrew; Bakke, Per; Wagner, Peter D. (Peer reviewed; Journal article, 2012-06-18)
    • Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD 

      Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hiemstra, Pieter Sicco; Michelsen, Annika; Ueland, Thor; Hardie, Jon Andrew; Aukrust, Pål; Bakke, Per S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2015-03-24)
      Background: Associations between Vitamin D3 [25(OH)D], vitamin D binding protein (VDBP) and chronic obstructive pulmonary disease (COPD) are previously reported. We aimed to further investigate these associations on ...