Browsing Department of Clinical Science by Title
Now showing items 457-476 of 2289
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Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU
(Peer reviewed; Journal article, 2012-04-19)Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ... -
The course and determinants of post-traumatic stress over 12 months after hospitalization for COVID-19
(Journal article; Peer reviewed, 2022)Objective: To assess the trajectory of symptoms and symptom-defined post-traumatic stress disorder (PTSD) from 1.5 to 12 months after hospitalization for COVID-19 and determine risk factors for persistent symptoms and ... -
Covariables of Myocardial Function in Women and Men with Increased Body Mass Index
(Journal article; Peer reviewed, 2020)Introduction Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function ... -
Covid-19 hos pasienter med kronisk inflammatorisk leddsykdom
(Journal article; Peer reviewed, 2021)BAKGRUNN Siden pasienter med kronisk inflammatorisk leddsykdom kan være mer utsatt for infeksjoner, ønsket vi å undersøke forekomsten av covid-19 i denne gruppen og se om forhold ved den revmatiske sykdommen, pasienten ... -
COVID-19 myocarditis and postinfection Bell’s palsy
(Journal article; Peer reviewed, 2021)Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ... -
COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021
(Journal article; Peer reviewed, 2022)Purpose: We compared the prevalence of COVID-19 and related mortality in nursing homes (NHs) in 14 countries until October 2021. We explored the relationship between COVID-19 mortality in NHs with the average size of NHs ... -
Cow Farmers’ Homes Host More Diverse Airborne Bacterial Communities Than Pig Farmers’ Homes and Suburban Homes
(Journal article; Peer reviewed, 2022)Living on a farm has been linked to a lower risk of immunoregulatory disorders, such as asthma, allergy, and inflammatory bowel disease. It is hypothesized that a decrease in the diversity and composition of indoor microbial ... -
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
(Peer reviewed; Journal article, 2016-10-24)Background: Tuberculosis (TB) causes a major burden on global health with long and cumbersome TB treatment regimens. Host-directed immune modulating therapies have been suggested as adjunctive treatment to TB antibiotics. ... -
Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease
(Peer reviewed; Journal article, 2019-09-09)Purpose: We hypothesized that biomarkers and dietary factors related to cardiovascular disease risk were associated with serum retinol and evaluated these potential associations in patients with suspected coronary artery ... -
A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part I: The randomized controlled trials
(Peer reviewed; Journal article, 2014-06)We reappraised the five randomized controlled trials that compared cardiotocography plus ECG ST interval analysis (CTG+ST) vs. cardiotocography. The numbers enrolled ranged from 5681 (Dutch randomized controlled trial) to ... -
A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: The meta-analyses
(Peer reviewed; Journal article, 2014-06)We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials which compared cardiotocography (CTG)+ST analysis to cardiotocography. The ... -
Critical evaluation of the appetite test for children with severe acute malnutrition
(Peer reviewed; Journal article, 2020)OBJECTIVES: The appetite test is used to risk-stratify for children with severe acute malnutrition (SAM) in in-patient or out-patient care. The test is recommended in guidelines despite lack of evidence. We evaluated its ... -
Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids
(Peer reviewed; Journal article, 2015-10-28)Purpose: The cloned enzyme donor immunoassay (CEDIA) for buprenorphine is applied for both urine drugs-of-abuse screening and compliance monitoring. Sensitivity, specificity, and optimal cutoff of this assay have differed ... -
Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid
(Peer reviewed; Journal article, 2012-11-14)The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA ... -
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
(Journal article; Peer reviewed, 2023)C-reactive protein (CRP) tends to be elevated in individuals with psychiatric disorders. Recent findings have suggested a protective effect of the genetic liability to elevated CRP on schizophrenia risk and a causative ... -
Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes
(Peer reviewed; Journal article, 2014-12)Heat Shock Factor 1 (HSF1) is the primary transcription factor responsible for the response to cellularstress, while HSF2 becomes activated during development and differentiation, including spermatogen-esis. Although both ... -
Cryoballoon vs. radiofrequency catheter ablation: insights from NOrwegian randomized study of PERSistent Atrial Fibrillation (NO-PERSAF study)
(Journal article; Peer reviewed, 2022)Aims Pulmonary vein isolation (PVI) is still regarded as a cornerstone for treatment of persistent atrial fibrillation (AF). This study evaluated the effectiveness of PVI performed with cryoballoon ablation (CBA) in ... -
Cryptosporidiosis in low-resource healthcare settings : Near-patient diagnostics, risk factors, and parasite shedding dynamics in young Ethiopian children
(Doctoral thesis, 2023-04-28)Bakgrunn: Tarmparasitten Cryptosporidium er en ledende årsak til diaré og dødsfall hos småbarn i lavinntektsland. Målretta behandling trengs, men forutsetter presise diagnostiske tester som er egna for ressursfattige ... -
Cryptosporidium Infections in Africa—How Important Is Zoonotic Transmission? A Review of the Evidence
(Journal article; Peer reviewed, 2020)Cryptosporidium, a protozoan parasite in the phylum Apicomplexa, is the etiological agent of cryptosporidiosis, an intestinal infection characterized by profuse watery diarrhea. Over 30 species of Cryptosporidium are ... -
CT-defined emphysema in COPD patients and risk for change in desaturation status in 6-min walk test
(Journal article; Peer reviewed, 2021)Background Emphysema and exercise induced desaturation (EID) are both related to poorer COPD prognosis. More knowledge of associations between emphysema and desaturation is needed for more efficient disease management. ...