Blar i Department of Clinical Science på tittel

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    • Endometrial ablation; less is more? Historical cohort study comparing long-term outcomes from two time periods and two treatment modalities for 854 women 

      Helleland, Liva; Bergesen, Lena Flekke; Rinnan, Karen Jakobsen; Engelsen, Ingeborg Bøe; Hordnes, Knut; Trovik, Jone (Peer reviewed; Journal article, 2019-07-10)
      Background: Abnormal uterine bleeding needs surgical treatment if medical therapy fails. After introduction of non-hysteroscopic endometrial ablation as alternative to hysteroscopic endometrial resection, we aimed to compare ...

    • Endometrial carcinoma: a step closer to individualized therapy? Exploring transcriptional alterations in relation to prognostic biomarkers 

      Wik, Elisabeth (Doctoral thesis, 2013-09-30)
      Background: Endometrial cancer is diagnosed early and has in general a good prognosis. The more important it is to diagnose and treat the poor-prognosis cases. Therapy of endometrial carcinoma patients per today is to a ...

    • Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation 

      Papp, Bela; Launay, Sophie; Gelebart, Pascal; Arbabian, Atousa; Enyedi, Agnes; Brouland, Jean-Philippe; Carosella, Edgardo D.; Adle-Biassette, Homa (Journal article; Peer reviewed, 2020)
      Endoplasmic reticulum (ER) calcium homeostasis plays an essential role in cellular calcium signaling, intra-ER protein chaperoning and maturation, as well as in the interaction of the ER with other organelles. Calcium is ...

    • Endothelial dysfunction in ME/CFS patients 

      Sandvik, Miriam Kristine; Sørland, Kari; Leirgul, Elisabeth; Rekeland, Ingrid Gurvin; Stavland, Christina Særsten; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2023-02-02)
      Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial ...

    • Endurance exercise training volume is not associated with progression of coronary artery calcification 

      Kleiven, Øyunn; Bjørkavoll-Bergseth, Magnus; Omland, Torbjørn; Aakre, Kristin Moberg; Frøysa, Vidar; Erevik, Christine B.; Greve, Ole Jacob; Melberg, Tor Harald; Auestad, Bjørn Henrik; Skadberg, Øyvind; Edvardsen, Thor; Ørn, Stein (Journal article; Peer reviewed, 2020)
      Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ...

    • Energy intake, nutritional status and weight reduction in patients one year after laparoscopic sleeve gastrectomy 

      Gjessing, Hanne Rosendahl; Nielsen, Hans Jørgen; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2013-07-30)
      Background: Laparoscopic sleeve gastrectomy (LSG) is increasingly popular due to its efficiency in reducing excess weight, however little is known about the nutritional status in patients after surgery. Purpose: To investigate ...

    • Enhanced T-lymphocyte infiltration in a desmoid tumor of the thoracic wall in a young woman treated with intratumoral injections of the oncolytic peptide LTX-315: A case report 

      Jebsen, Nina Louise; Apelseth, Torunn Oveland; Haugland, Hans Kristian; Rekdal, Øystein; Patel, Hamina; Gjertsen, Bjørn Tore; Jøssang, Dag Eirik (Peer reviewed; Journal article, 2019-06-10)
      Background: Desmoid tumors are intermediary malignant, fibrous lesions occurring in various soft tissues. Surgical treatment is relentlessly challenging because of the propensity for local aggressive behavior and high risk ...

    • Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles 

      Prandina, Anthony; Herfindal, Lars; Radix, S; Rongved, Pål; Doskeland, Stein Ove; Le Borgne, Marc; Perret, F (Journal article; Peer reviewed, 2018)
      Phenazine is known to regroup planar nitrogen-containing heterocyclic compounds. It was used here to enhance the bioavailability of the biologically important compound iodinin, which is near insoluble in aqueous solutions. ...

    • Enhancing potential impact of hospital discharge interventions for patients with COPD: a qualitative systematic review 

      Nygård, Torbjørn; Wright, David; Nazar, Hamde; Haavik, Svein (Journal article; Peer reviewed, 2023-06-22)
      Background: Patients with chronic obstructive pulmonary disease (COPD) are frequently readmitted to hospital resulting in avoidable healthcare costs. Many different interventions designed to reduce hospital readmissions ...

    • Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit 

      Argyropoulos, Christos D.; Leckler, Janina; Salmanton-García, Jon; Constantinou, Marinos; Alexandrou, Alexandra; Themistocleous, Sophia; Noula, Evgenia; Shiamakkides, George; Nearchou, Andria; Stewart, Fiona A.; Albus, Kerstin; Koniordou, Markela; Kopsidas, Ioannis; Spivak, Orly; Hellemans, Margot; Hendrickx, Greet; Davis, Ruth Joanna; Azzini, Anna Maria; Simon, Paula Valle; Carcas-Sansuan, Antonio Javier; Askling, Helena Hervius; Vene, Sirkka; Prellezo, Jana Baranda; Álvarez-Barco, Elena; Macken, Alan J.; Di Marzo, Romina; Luís, Catarina; Olesen, Ole F.; Frias Iniesta, Jesus A.; Barta, Imre; Tóth, Krisztina; Akova, Murat; Bonten, Marc M.J.; Cohen-Kandli, Miriam; Cox, Rebecca Jane; Součková, Lenka; Husa, Petr; Jancoriene, Ligita; Launay, Odile; Lundgren, Jens; Mallon, Patrick; Armeftis, Charis; Marques, Laura; Naucler, Pontus; Ochando, Jordi; Tacconelli, Evelina; van Damme, Pierre; Zaoutis, Theoklis; Hofstraat, Sanne; Bruijning-Verhagen, Patricia; Zeitlinger, Markus; Cornely, Oliver A.; Pana, Zoi Dorothea (Journal article; Peer reviewed, 2023)
      Background: The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale ...

    • Enrichment of genetic markers of recent human evolution in educational and cognitive traits 

      Srinivasan, Saurabh; Bettella, Francesco; Frei, Oleksandr; Hill, W. David; Wang, Yunpeng; Witoelar, Aree; Schork, Andrew J.; Thompson, Wesley Kurt; Davies, Gail; Desikan, Rahul S.; Deary, Ian J.; Melle, Ingrid; Ueland, Torill; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2018-08-22)
      Higher cognitive functions are regarded as one of the main distinctive traits of humans. Evidence for the cognitive evolution of human beings is mainly based on fossil records of an expanding cranium and an increasing ...

    • Environmental pollutants in blood donors: The multicentre Norwegian donor study 

      Averina, Maria; Hervig, Tor; Huber, Sandra; Kjær, Mette; Kristoffersen, Einar Klæboe; Bolann, Bjørn Johan (Journal article; Peer reviewed, 2020)
      Objectives The aim of this study was to measure blood concentrations of environmental pollutants in Norwegian donors and evaluate the risk of pollutant exposure through blood transfusions. Background Transfused blood ...

    • Eosinophilic airway diseases: basic science, clinical manifestations and future challenges 

      Janson, Christer; Bjermer, Leif; Lehtimäki, Lauri; Kankaanranta, Hannu; Karjalainen, Jussi; Altraja, Alan; Yasinska, Valentyna; Aarli, Bernt Bøgvald; Rådinger, Madeleine; Hellgren, Johan; Lofdahl, Magnus; Howarth, Peter H; Porsbjerg, Celeste (Journal article; Peer reviewed, 2022)
      Eosinophils have a broad range of functions, both homeostatic and pathological, mediated through an array of cell surface receptors and specific secretory granules that promote interactions with their microenvironment. ...

    • Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease 

      Khan, Ingela; Berge, Caroline Annette; Eskerud, Ingeborg; Larsen, Terje Hjalmar; Pedersen, Eva Ringdal; Lønnebakken, Mai Tone (Journal article; Peer reviewed, 2023)
      Background Epicardial adipose tissue (EAT) accumulation has been associated with inflammation, atherosclerosis and microvascular dysfunction. Whether increased EAT volume is associated with coronary plaque vulnerability ...

    • An epidemiological study on the associations between preeclampsia exposure, growth and physical activity in preschool age and subsequent allergy, asthma and lung function in late childhood 

      Byberg, Kristine Kjer (Doctoral thesis, 2017-10-13)
      Background An adverse intrauterine environment may affect offspring immunology, including allergies, asthma and lung function, as well as offspring metabolism, including growth and development. A few studies have been ...

    • The epidemiology and characteristics of sepsis in Norwegian hospitals 

      Knoop, Siri Tandberg (Doctoral thesis, 2018-06-08)
      Background: Sepsis develops when the host’s immune response to infection becomes dysregulated to such an extent that life-threatening organ dysfunction evolves. Sepsis epidemiology is influenced by population characteristics, ...

    • Epidemiology and etiology of primary ovarian insuffciency 

      Vogt, Elinor Chelsom (Doctoral thesis, 2023-03-02)
      Bakgrunn: Primær ovarialinsuffisiens (POI) er forårsaket av utilstrekkelig ovarieaktivitet og resulterer i for tidlig overgangsalder (alder <40 år). Diagnosen POI har livsendrende konsekvenser på grunn av infertilitet og ...

    • Epidemiology and health related quality of life in hypoparathyroidism in Norway 

      Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...

    • Epidemiology and impact on all-cause mortality of sepsis in Norwegian hospitals: A national retrospective study 

      Knoop, Siri Tandberg; Skrede, Steinar; Langeland, Nina; Flaatten, Hans (Peer reviewed; Journal article, 2017-11-17)
      Background: Although sepsis is the leading cause of death from infection, there are few population-level epidemiological sepsis reports. The impact of sepsis-related deaths on all-cause hospital mortality is insufficiently ...

    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Journal article; Peer reviewed, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...