Browsing Department of Clinical Science by Title

Now showing items 692-711 of 2283

    • The epidemiology and characteristics of sepsis in Norwegian hospitals 

      Knoop, Siri Tandberg (Doctoral thesis, 2018-06-08)
      Background: Sepsis develops when the host’s immune response to infection becomes dysregulated to such an extent that life-threatening organ dysfunction evolves. Sepsis epidemiology is influenced by population characteristics, ...

    • Epidemiology and etiology of primary ovarian insuffciency 

      Vogt, Elinor Chelsom (Doctoral thesis, 2023-03-02)
      Bakgrunn: Primær ovarialinsuffisiens (POI) er forårsaket av utilstrekkelig ovarieaktivitet og resulterer i for tidlig overgangsalder (alder <40 år). Diagnosen POI har livsendrende konsekvenser på grunn av infertilitet og ...

    • Epidemiology and health related quality of life in hypoparathyroidism in Norway 

      Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...

    • Epidemiology and impact on all-cause mortality of sepsis in Norwegian hospitals: A national retrospective study 

      Knoop, Siri Tandberg; Skrede, Steinar; Langeland, Nina; Flaatten, Hans (Peer reviewed; Journal article, 2017-11-17)
      Background: Although sepsis is the leading cause of death from infection, there are few population-level epidemiological sepsis reports. The impact of sepsis-related deaths on all-cause hospital mortality is insufficiently ...

    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Journal article; Peer reviewed, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...

    • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer 

      Shen, Hui; Fridley, BL; Song, HL; Lawrenson, K; Cunningham, JM; Ramus, SJ; Cicek, MS; Tyrer, J; Stram, D; Larson, MC; Kobel, M; Ziogas, A; Zheng, W; Yang, HP; Wu, AH; Wozniak, EL; Woo, YL; Winterhoff, B; Wik, Elisabeth; Whittemore, AS; Wentzensen, N; Weber, RP; Vitonis, AF; Vincent, D; Vierkant, RA; Vergote, I; Van Den Berg, D; Van Altena, AM; Tworoger, SS; Thompson, PJ; Tessier, DC; Terry, KL; Teo, SH; Templeman, C; Stram, DO; Southey, MC; Sieh, W; Siddiqui, N; Shvetsov, YB; Shu, XO; Shridhar, V; Wang-Gohrke, S; Severi, G; Schwaab, I; Salvesen, Helga Birgitte; Rzepecka, IK; Runnebaum, IB; Rossing, MA; Rodriguez-Rodriguez, L; Risch, HA; Renner, SP; Poole, EM; Pike, MC; Phelan, CM; Pelttari, LM; Pejovic, T; Paul, J; Orlow, I; Omar, SZ; Olson, SH; Odunsi, K; Nickels, S; Nevanlinna, H; Ness, RB; Narod, SA; Nakanishi, T; Moysich, KB; Monteiro, ANA; Moes-Sosnowska, J; Modugno, F; Menon, U; McLaughlin, JR; McGuire, V; Matsuo, K; Adenan, NAM; Massuger, LFAG; Lurie, G; Lundvall, L; Lubinski, J; Lissowska, J; Levine, DA; Leminen, A; Lee, AW; Le, ND; Lambrechts, S; Lambrechts, D; Kupryjanczyk, J; Krakstad, Camilla; Konecny, GE; Kjaer, SK; Kiemeney, LA; Kelemen, LE; Keeney, GL; Karlan, BY; Karevan, R; Kalli, KR; Kajiyama, H; Ji, BT; Jensen, A; Jakubowska, A; Iversen, E; Hosono, S; Hogdall, CK; Hogdall, E; Hoatlin, M; Hillemanns, P; Heitz, F; Hein, R; Harter, P; Halle, Mari Kyllesø; Hall, P; Gronwald, J; Gore, M; Goodman, MT; Giles, GG; Gentry-Maharaj, A; Garcia-Closas, M; Flanagan, JM; Fasching, PA; Ekici, AB; Edwards, R; Eccles, D; Easton, DF; Durst, M; du Bois, A; Dork, T; Doherty, JA; Despierre, E; Dansonka-Mieszkowska, A; Cybulski, C; Cramer, DW; Cook, LS; Chen, XQ; Charbonneau, B; Chang-Claude, J; Campbell, I; Butzow, R; Bunker, CH; Brueggmann, D; Brown, R; Brooks-Wilson, A; Brinton, LA; Bogdanova, N; Block, MS; Benjamin, E; Beesley, J; Beckmann, MW; Bandera, EV; Baglietto, L; Bacot, F; Armasu, SM; Antonenkova, N; Anton-Culver, H; Aben, KK; Liang, D; Wu, XF; Lu, KR; Hildebrandt, MAT; Schildkraut, JM; Sellers, TA; Huntsman, D; Berchuck, A; Chenevix-Trench, G; Gayther, SA; Pharoah, PDP; Laird, PW; Goode, EL; Pearce, CL (Peer reviewed; Journal article, 2013-03-27)
      HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with ...

    • An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD 

      Løkhammer, Solveig; Stavrum, Anne-Kristin Støbakk; Polushina, Tatiana; Aas, Monica; Ottesen, Akiah; Andreassen, Ole; Melle, Ingrid; Hellard, Stephanie Francoise Claire Le (Journal article; Peer reviewed, 2022)
      Patients with a severe mental disorder report significantly higher levels of childhood trauma (CT) than healthy individuals. Studies have suggested that CT may affect brain plasticity through epigenetic mechanisms and ...

    • Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study 

      Knudsen, Gerd Toril Mørkve; Rezwan, FI; Johannessen, Ane; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gomez Real, Francisco; Krauss-Etschmann, Susanne; Patil, Viswanath; Jarvis, Deborah; Arshad, SH; Holloway, John W; Svanes, Cecilie (Peer reviewed; Journal article, 2019)
      Epidemiological studies suggest that father’s smoking might influence their future children’s health, but few studies have addressed whether paternal line effects might be related to altered DNA methylation patterns in the ...

    • ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility 

      Rostad, Kari (Doctoral thesis, 2011-01-27)

    • Escherichia marmotae—a Human Pathogen Easily Misidentified as Escherichia coli 

      Sivertsen, Audun; Dyrhovden, Ruben; Tellevik, Marit Gjerde; Bruvold, Torbjørn Sæle; Nybakken, Eirik Jovall; Skutlaberg, Dag Harald; Skarstein, Ingerid; Kommedal, Øyvind (Journal article; Peer reviewed, 2022)
      We hereby present the first descriptions of human-invasive infections caused by Escherichia marmotae, a recently described species that encompasses the former “Escherichia cryptic clade V.” We describe four cases, one acute ...

    • Estimating cardiac output from coronary CT angiography: an individualized compartment model in comparison to the Stewart–Hamilton method 

      Leiknes, Jon Bjarne; Hiorth, Aksel; Havnen, Jorunn; Greve, Ole Jacob; Kurz, Kathinka Dæhli; Larsen, Alf Inge (Journal article; Peer reviewed, 2023)
      Background: Attenuation is correlated with the concentration of contrast medium (CM) in the arteries. The cardiac output (CO) affects the concentration of CM in the circulatory system; therefore, CO affects the time–density ...

    • Estimating the within-subject (CVI) and between-subject (CVG) biological variation of serum tryptase 

      Skarbø, Birthe Rochlenge Skarbø; Vinnes, Erik Wilhelm; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2021)
      Background Tryptase is used as a biomarker to support the diagnosis of anaphylaxis and hematologic diseases. In the event of a mast cell activation during anaphylaxis, a temporary increase in the concentration of tryptase ...

    • The European Cardiac Resynchronization Therapy (CRT) Survey 

      Bogale, Nigussie (Doctoral thesis, 2011-10-20)
      Aims: The European Cardiac Resynchronization Therapy (CRT) Survey was a joint initiative taken by the Heart Failure (HFA) and the European Heart Rhythm (EHRA) Associations of the European Society of Cardiology (ESC) designed ...

    • European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma 

      Sorbye, Halfdan; Grande, Enrique; Pavel, Marianne; Tesselaar, Margot; Fazio, Nicola; Reed, Nicholas Simon; Knigge, Ulrich; Christ, Emanuel; Ambrosini, Valentina; Couvelard, Anne; Tiensuu Janson, Eva (Journal article; Peer reviewed, 2023)
      This ENETS guidance paper, developed by a multidisciplinary working group, provides up-to-date and practical advice on the diagnosis and management of digestive neuroendocrine carcinoma, based on recent developments and ...

    • Evaluating national guidelines for monitoring early growth using routinely collected data in Bergen, Norway 

      Balthasar, Melissa Rajini; Roelants, Mathieu; Brannsether-Ellingsen, Bente; Stangenes, Kristine Marie; Magnus, Maria Christine; Håberg, Siri Eldevik; Øverland, Simon Nygaard; Juliusson, Pétur Benedikt (Journal article; Peer reviewed, 2023)
      Aims: The overarching aim of this study was to evaluate the Norwegian guidelines for growth monitoring using routinely collected data from healthy children up to five years of age. We analysed criteria for both status ...

    • Evaluating the suitability of the Low Energy Availability in Females Questionnaire (LEAF-Q) for female footballers 

      Dasa, Marcus Småvik; Friborg, Oddgeir; Kristoffersen, Morten; Pettersen, Gunn; Sagen, Jørn Vegard; Sundgot-Borgen, Jorunn; Rosenvinge, Jan H (Journal article; Peer reviewed, 2023)
      Background The Low Energy Availability in Females Questionnaire (LEAF-Q) is a screening tool developed to detect endurance athletes and dancers at risk for development of persistent low energy availability (LEA) and the ...

    • Evaluating Translational Methods for Personalized Medicine—A Scoping Review 

      Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Gerardi, Chiara; Banzi, Rita; Fratelli, Maddalena; Bietrix, Florence; Ussi, Anton; Andreu, Antonio L.; McCormack, Emmet (Journal article; Peer reviewed, 2022)
      The introduction of personalized medicine, through the increasing multi-omics characterization of disease, brings new challenges to disease modeling. The scope of this review was a broad evaluation of the relevance, validity, ...

    • Evaluation of interferon-beta neutralizing antibodies in individual patients with multiple sclerosis based on phospho-specific flow cytometry 

      Gavasso, Sonia (Doctoral thesis, 2013-03-19)
      Background: Recombinant human interferon-beta (IFN-β) is the most frequently used drug for treating relapsing-remitting multiple sclerosis (RRMS), a demyelinating disease of the central nervous system. It modulates the ...

    • Evaluation of the Rosa Chatbot Providing Genetic Information to Patients at Risk of Hereditary Breast and Ovarian Cancer: Qualitative Interview Study 

      Siglen, Elen; Vetti, Hildegunn Høberg; Augestad, Mirjam Tonheim; Steen, Vidar Martin; Lunde, Åshild; Bjorvatn, Cathrine (Journal article; Peer reviewed, 2023)
      Background: Genetic testing has become an integrated part of health care for patients with breast or ovarian cancer, and the increasing demand for genetic testing is accompanied by an increasing need for easy access to ...

    • Evaluation of the sublingual route for administration of influenza vaccines in a murine model 

      Gjeraker, Ingrid Hjetland (Master thesis, 2011-05-19)
      Influenza is a one of the most important respiratory viruses, and it infects millions of people every year. Due to mutational changes in the virus genome (antigenic drift), influenza cause occasional pandemics. Pandemic ...