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    • Exhaled nitric oxide is related to atopy, but not asthma in adolescents with bronchiolitis in infancy 

      Mikalsen, Ingvild Bruun; Halvorsen, Thomas; Øymar, Knut (Peer reviewed; Journal article, 2013-11-17)
      Background: The fraction of exhaled nitric oxide (FeNO) has been suggested as a non-invasive marker of eosinophilic inflammation in asthma, but lately rather as a biomarker of atopy than of asthma itself. Asthma after ...

    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...

    • Exome chip analyses in adult attention deficit hyperactivity disorder 

      Zayats, Tetyana; Jacobsen, Kaya Kvarme; Kleppe, Rune; Jacob, CP; Kittel-Schneider, Sarah; Ribases, Marta; Ramos-Quiroga, JA; Richarte, Vanesa; Casas, M; Mota, NR; Grevet, EH; Klein, M; Corominas, J; Bralten, Janita; Galesloot, T; Vasquez, AA; Herms, S; Forstner, AJ; Larsson, H; Breen, G; Asherson, P; Gross-Lesch, Silke; Lesch, KP; Cichon, Sven; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Bau, CH; Buitelaar, Jan; Kiemeney, L; Faraone, Stephen V.; Cormand, B; Franke, Barbara; Reif, Andreas; Haavik, Jan; Johansson, Stefan (Peer reviewed; Journal article, 2016)
      Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ...

    • Experimental Infection of Human Volunteers with the Heat-Stable Enterotoxin-Producing Enterotoxigenic Escherichia coli Strain TW11681 

      Sakkestad, Sunniva Todnem; Steinsland, Hans; Skrede, Steinar; Kleppa, Elisabeth; Lillebø, Kristine; Sævik, Marianne; Søyland, Hanne; Heien, Astrid Rykkje; Tellevik, Marit Gjerde; Barry, Eileen M.; Sommerfelt, Halvor; Hanevik, Kurt (Peer reviewed; Journal article, 2019-06-22)
      Infection with enterotoxigenic Escherichia coli (ETEC) producing the heat-stable enterotoxin (ST) is one of the most important causes of childhood diarrhoea in low- and middle-income countries. Here, we undertook a controlled ...

    • An expert consensus on the recommendations for the use of biomarkers in Fabry disease 

      Burlina, Allesandro; Brand, Eva; Hughes, Derralynn A.; Kantola, Ilkka; Krämer, Johannes; Nowak, Albina; Tøndel, Camilla; Wanner, Christoph; Spada, Marco (Journal article; Peer reviewed, 2023)
      Fabry disease is an X-linked lysosomal storage disorder caused by the accumulation of glycosphingolipids in various tissues and body fluids, leading to progressive organ damage and life-threatening complications. Phenotypic ...

    • Expert opinion of mediastinal lymph node positions from an intrabronchial view 

      Roth, Kjetil; Eagan, Tomas; Hardie, Jon (Peer reviewed; Journal article, 2016-01-22)
      Background The knowledge of the mediastinal lymph node positions from an intrabronchial view was important for conventional transbronchial needle aspiration (TBNA). The introduction of endobronchial ultrasound guided ...

    • Exploration of Cellular Signaling Patterns for the Stratification of Patients with Rheumatoid Arthritis 

      Bader, Lucius (Doctoral thesis, 2020-09-16)
      Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by synovial inflammation that, if not treated early and efficiently, causes joint damage. The proinflammatory cytokine tumor necrosis ...

    • Exploration of the Cellular Microenvironment in Minor Salivary Glands of Primary Sjögren's Patients by Imaging Mass Cytometry 

      Helgesen, Ylva Bratterud (Master thesis, 2022-05-20)

    • Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study 

      Anfinsen, Åslaug Matre; Rosendahl-Riise, Hanne; Nygård, Ottar Kjell; Tell, Grethe S.; Ueland, Per Magne; Ulvik, Arve; McCann, Adrian; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)
      Purpose Dietary intake may have pronounced effects on circulating biomarker concentrations. Therefore, the aim was to provide a descriptive overview of serum metabolite concentrations in relation to time since last meal, ...

    • Exploring and redefining Autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind (Doctoral thesis, 2019-02-08)
      Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, monogenic, childhood-onset disorder caused by mutations in the autoimmune regulator (AIRE) gene. Multi-organ autoimmune disease and chronic mucocutaneous candidiasis ...

    • Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study 

      Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn; Ersland, Kari Merete; Hansson, Lars Johan Axel; Bahrami, Shahram; Andreassen, Ole Andreas; Steen, Vidar Martin; Djurovic, Srdjan; Hughes, Timothy (Peer reviewed; Journal article, 2019)
      Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to ...

    • Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4 

      Drengenes, Christine; Eagan, Tomas Mikal; Haaland, Ingvild; Wiker, Harald G; Nielsen, Rune (Journal article; Peer reviewed, 2021)
      Background Studies on the airway microbiome have been performed using a wide range of laboratory protocols for high-throughput sequencing of the bacterial 16S ribosomal RNA (16S rRNA) gene. We sought to determine the ...

    • Exploring the boundaries of precision haemato-oncology : The case of FLT3 length mutated acute myeloid leukaemia 

      Engen, Caroline Benedicte Nitter (Doctoral thesis, 2020-02-14)
      This dissertation explores the astounding biological heterogeneity of acute myeloid leukaemia (AML). In three research papers, we study FLT3 length mutated (LM) AML to contribute to the characterisation of genetic diversity ...

    • Exploring the Patient Perspective of Bone Sarcoma Survivors Who Have Undergone Particle Radiotherapy Abroad 

      Fauske, Lena; Jebsen, Nina Louise; Bondevik, Hilde; Bruland, Øyvind (Journal article; Peer reviewed, 2023)
      Background/Aim: Sarcoma patients’ experiences of their health-related quality of life and late effects following particle therapy are sparse. Such knowledge is essential to optimize treatment compliance and follow-up care ...

    • Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder 

      Hoseth, Eva Zsuzsanna; Krull, Florian; Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Gardsjord, Erlend Strand; Steen, Nils Eiel; Melle, Ingrid; Brattbakk, Hans-Richard; Steen, Vidar Martin; Aukrust, Pål; Djurovic, Srdjan; Andreassen, Ole Andreas; Ueland, Thor (Peer reviewed; Journal article, 2018)
      The Wnt signaling pathway plays a crucial role in neurodevelopment and in regulating the function and structure of the adult nervous system. Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders with ...

    • Exposure to Antibacterial Chemicals Is Associated With Altered Composition of Oral Microbiome 

      Vindenes, Hilde Kristin; Lin, Huang; Shigdel, Rajesh; Ringel-Kulka, Tamar; Real, Francisco Gomez; Svanes, Cecilie; Peddada, Shyamal D.; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2022)
      Antimicrobial chemicals are used as preservatives in cosmetics, pharmaceuticals, and food to prevent the growth of bacteria and fungi in the products. Unintentional exposure in humans to such chemicals is well documented, ...

    • Exposure to preeclampsia growth from birth to late childhood dependent on child’s sex and severity of exposure: Follow-up of a nested case-control study 

      Byberg, Kristine Kjer; Øymar, Knut; Eide, Geir Egil; Forman, Michele R.; Júlíusson, Pétur Benedikt (Peer reviewed; Journal article, 2017-05-09)
      Background and objective An adverse intrauterine environment may affect offspring growth and development. Our aim was to explore whether preeclampsia (PE) exposure in utero influences growth from birth to 13 years. Methods ...

    • The expressed mutational landscape of microsatellite stable colorectal cancers 

      Sveen, Anita; Johannessen, Bjarne; Eilertsen, Ina Andrassy; Røsok, Bård Ingvald; Gulla, Marie; Eide, Peter Andreas Wold; Bruun, Jarle; Kryeziu, Kushtrim; Meza, Leonardo Zepeda; Myklebost, Ola; Bjørnbeth, Bjørn Atle; Skotheim, Rolf I.; Nesbakken, Arild; Lothe, Ragnhild Adelheid (Journal article; Peer reviewed, 2021)
      Background Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients benefiting from biomarker-guided therapy. Mutation expression is essential for accurate interpretation of mutations as ...

    • Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders 

      Aas, Monica; Andreassen, Ole; Gjerstad, Johannes; Rødevand, Linn; Hjell, Gabriela; Johansen, Ingrid Torp; Lunding, Synve Hoffart; Ormerod, Monica Bettina E. Greenwood; Lagerberg, Trine Vik; Steen, Nils Eiel; Djurovic, Srdjan; Akkouh, Ibrahim Ahmed (Journal article; Peer reviewed, 2023)
      Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in ...

    • The expression of B & T cell activation markers in children’s tonsils following live attenuated influenza vaccine 

      Panapasa, Jack A.; Cox, Rebecca Jane; Mohn, Kristin Greve-Isdahl; Aqrawi, Lara Adnan; Brokstad, Karl Albert (Peer reviewed; Journal article, 2015-07-06)
      Live attenuated influenza vaccines (LAIV) can prevent influenza illness and death in children. The absence of known correlates of protection induced by LAIV requires human studies of underlying mechanisms of vaccine-induced ...