Now showing items 912-931 of 1167

    • Prevention of Hypertension and Organ Damage in 2-Kidney, 1-Clip Rats by Tetradecylthioacetic Acid 

      Gudbrandsen, Oddrun Anita; Hultström, Michael; Leh, Sabine Maria; Bivol, Liliana Monica; Vågnes, Øyvind; Berge, Rolf Kristian; Iversen, Bjarne M. (Peer reviewed; Journal article, 2006-07-17)
      Dietary lipids are reported to affect the blood pressure in both humans and experimental animal models with hypertension. In the present study, 2-kidney, 1-clip (2K1C) hypertensive rats were treated with the modified fatty ...
    • Prevention of urinary tract infections in nursing homes: lack of evidence-based prescription? 

      Bergman, Jenny; Schjøtt, Jan; Blix, Hege S. (Peer reviewed; Journal article, 2011-11-01)
      Background: Urinary tract infections (UTIs, including upper and lower symptomatic) are the most common infections in nursing homes and prevention may reduce patient suffering, antibiotic use and resistance. The spectre of ...
    • Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases 

      Grønning, Kaja; Sharma, Archana; Mastroianni, Maria Adele; Karlsson, Bo Daniel; Husebye, Eystein Sverre; Løvås, Kristian; Nermoen, Ingrid (Journal article; Peer reviewed, 2020-03)
      Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report ...
    • Primary aldosteronism in Western Norway. Studies of diagnostic approach and treatment outcome 

      Grytaas, Marianne Aardal (Doctoral thesis; Peer reviewed, 2018-09-06)
      Primary aldosteronism (PA) is the most common cause of secondary hypertension (HT), accounting for 5 to 12% of all hypertensive individuals. Patients with PA experience increased cardiovascular, renal and metabolic ...
    • Primary Hyperparathyroidism Influences the Expression of Inflammatory and Metabolic Genes in Adipose Tissue 

      Christensen, Monika H. E.; Dankel, Simon N.; Nordbø, Yngve; Varhaug, Jan Erik; Almås, Bjørg; Lien, Ernst Asbjørn; Mellgren, Gunnar (Peer reviewed; Journal article, 2011-06-17)
      Background: Primary hyperparathyroidism (PHPT) is characterised by increased production of parathyroid hormone (PTH) resulting in elevated serum calcium levels. The influence on bone metabolism with altered bone resorption ...
    • Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study 

      Mehl, Arne; Harthug, Stig; Lydersen, Stian; Paulsen, Julie; Åsvold, Bjørn Olav; Solligård, Erik; Damås, Jan Kristian; Edna, Tom-Harald (Peer reviewed; Journal article, 2015-03)
      n several studies on patients with bloodstream infection (BSI), prior use of statins has been associated with improved survival. Gram-positive and Gram-negative bacteria alert the innate immune system in different ways. ...
    • Produksjon av EPA- og DHA-konsentrat fra frysetørket silderogn og sildemelke ved hjelp av ureakompleksering 

      Nguyen, Thea (Master thesis, 2012-08-29)
      Herring roe and milt are high in omega-3 fatty acids that are proven to have various health benefits. The effects are best documented for cardiovascular disease, as well as inflammatory disorders such as arthritis. The ...
    • Prognostic impact of vitamin B6 metabolism in lung cancer 

      Galluzzi, Lorenzo; Vitale, Ilio; Senovilla, Laura; Olaussen, Ken André; Pinna, Guillaume; Eisenberg, Tobias; Goubar, Aïcha; Martins, Isabelle; Michels, Judith; Kratassiouk, Guerorgui; Carmona-Gutierrez, Didac; Scoazec, Marie; Vacchelli, Erika; Schlemmer, Frederic; Kepp, Oliver; Shen, Sheshi; Tailler, Maximilien; Niso-Santano, Mireia; Morselli, Eugenia; Criollo, Alfredo; Adjemian, Sandy; Jemaa, Mohamed; Chaba, Kariman; Pailleret, Claire; Michaud, Mickaël; Pietrocola, Federico; Tajeddine, Nicolas; Rouge, Thibault de La Motte; Araujo, Natalia; Morozova, Nadya; Robert, Thomas; Ripoche, Hugues; Commo, Frederic; Besse, Benjamin; Validire, Pierre; Fouret, Pierre; Robin, Angélique; Dorvault, Nicolas; Girard, Philippe; Gouy, Sébastien; Pautier, Patricia; Jägemann, Nora; Nickel, Ann-Christin; Marsili, Sabrina; Paccard, Caroline; Servant, Nicolas; Hupé, Philippe; Behrens, Carmen; Behnam-Motlagh, Paviz; Kohno, Kimitoshi; Cremer, Isabelle; Damotte, Diane; Alifano, Marco; Midttun, Øivind; Ueland, Per Magne; Lazar, Vladimir; Dessen, Philippe; Zischka, Hans; Chatelut, Etienne; Castedo, Maria; Madeo, Frank; Barillot, Emmanuel; Thomale, Jürgen; Wistuba, Ignacio Ivan; Sautes-Fridman, Catherine; Zitvogel, Laurence; Soria, Jean-Charles; Harel-Bellan, Annick; Kroemer, Guido (Peer reviewed; Journal article, 2012-08-30)
      Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we identified vitamin B6 metabolism as a central regulator of cisplatin ...
    • Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy 

      Pedersen, Kjetil Boye; Jacob, Havjin; Frikstad, Kari-Anne; Nesland, Jahn M; Mælandsmo, Gunhild; Dahl, Olav; Nesbakken, Arild; Flatmark, Kjersti (Peer reviewed; Journal article, 2016-08)
      Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, and there is a need for novel biomarkers to improve the selection of patients. The ...
    • Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway 

      Næsgaard, Patrycja A.; Pønitz, Volker; Aarsetøy, Hildegunn; Andersen, Trygve Brugger; Grundt, Heidi; Harris, William S; Staines, Harry; Nilsen, Dennis W.T. (Peer reviewed; Journal article, 2015)
      BACKGROUND: An inverse relationship between cardiovascular risk and levels of vitamin D and omega-3 index may exist. OBJECTIVES: To evaluate the prognostic utility of serum 25-hydroxyvitamin D [25(OH)D] in 871 patients ...
    • Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy 

      Cao, Maria Dung; Giskeødegård, Guro F.; Bathen, Tone Frost; Sitter, Beathe; Bofin, Anna; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S. (Peer reviewed; Journal article, 2012-01-25)
      Background: Today’s clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor metabolic changes in patients with locally advanced ...
    • Progression of renal disease. Pathogenetic aspects and treatment options 

      Leh, Sabine Maria (Doctoral thesis, 2012-02-17)
    • Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia 

      Zangenberg, Mike; Johansen, Øystein Haarklau; Abdissa, Alemseged; Eshetu, Beza; Kurtzhals, Jørgen Anders; Friis, Henrik; Sommerfelt, Halvor; Langeland, Nina; Hanevik, Kurt (Peer reviewed; Journal article, 2019)
      Objectives: To assess the prevalence of prolonged and persistent diarrhoea, to estimate their co‐occurrence with acute malnutrition and association with demographic and clinical factors. Methods: Case–control study where ...
    • A proposed method to investigate reliability throughout a questionnaire 

      Wentzel-Larsen, Tore; Norekvål, Tone M.; Ulvik, Bjørg; Nygård, Ottar; Pripp, Are Hugo (Peer reviewed; Journal article, 2011-10-05)
      Background: Questionnaires are used extensively in medical and health care research and depend on validity and reliability. However, participants may differ in interest and awareness throughout long questionnaires, which ...
    • A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen-UVA photochemical treatment 

      Knutson, Folkre; Osselaer, Jean Claude; Pierelli, Luca; Lozano, Miguel; Cid, Joan Rodríguez; Tardivel, René H.; Garraud, Olivier; Hervig, Tor; Domanović, Dragoslav; Cukjati, Marko; Gudmundsson, Sveinn; Hjálmarsdóttir, Ína B.; Castrillo, Azucena; González, Rocío; Brihante, Dialina; Santos, Marlene; Schlenke, Peter; Elliott, Anne; Lin, Jin-Sying; Tappe, David; Stassinopoulos, Adonis; Green, Jennifer M.; Corash, Larry (Peer reviewed; Journal article, 2015-05-15)
      Background and Objectives: A photochemical treatment process (PCT) utilizing amotosalen and UVA light (INTERCEPT™ Blood System) has been developed for inactivation of viruses, bacteria, parasites and leucocytes that can ...
    • A protein extract from chicken reduces plasma homocysteine in rats 

      Lysne, Vegard; Bjørndal, Bodil; Vik, Rita; Nordrehaug, Jan Erik; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-06-04)
      The present study aimed to evaluate effects of a water-soluble protein fraction of chicken (CP), with a low methionine/glycine ratio, on plasma homocysteine and metabolites related to homocysteine metabolism. Male Wistar ...
    • Protein Post-Translational Modification Crosstalk in Acute Myeloid Leukemia Calls for Action 

      Hernandez-Valladares, Maria; Wangen, Rebecca; Berven, Frode; Guldbrandsen, Astrid (Peer reviewed; Journal article, 2019)
      Background: Post-translational modification (PTM) crosstalk is a young research field. However, there is now evidence of the extraordinary characterization of the different proteoforms and their interactions in a biological ...
    • Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid 

      Berle, Magnus; Kroksveen, Ann Cathrine; Haaland, Øystein; Aye, Thin T.; Opsahl, Jill Anette; Oveland, Eystein; Wester, Knut; Ulvik, Rune Johan; Helland, Christian Andre; Berven, Frode S. (Peer reviewed; Journal article, 2011-05-20)
      Background: The mechanisms behind formation and filling of intracranial arachnoid cysts (AC) are poorly understood. The aim of this study was to evaluate AC fluid by proteomics to gain further knowledge about ACs. Two goals ...
    • Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database 

      De Souza, Gustavo A.; Arntzen, Magnus Øverlie; Fortuin, Suereta; Schürch, Anita; Målen, Hiwa; McEvoy, Christopher R.; Van Soolingen, Dick; Thiede, Bernd; Warren, Robin M.; Wiker, Harald G. (Peer reviewed; Journal article, 2011-01)
      Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...