Browsing Department of Clinical Science by Title
Now showing items 629-648 of 2390
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E-Learning. A study of students’ attitudes and learning outcome when using blended learning with integration of multimedia instructions
(Doctoral thesis, 2012-09-06)The advent of new technologies has provided opportunities and challenges for education institutions to seek more effective ways of teaching and learning. Elearning is now an established phenomenon in education and institutions ... -
The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α
(Peer reviewed; Journal article, 2018-08-24)The transcription factor hepatocyte nuclear factor-1α (HNF-1A) is involved in normal pancreas development and function. Rare variants in the HNF1A gene can cause monogenic diabetes, while common variants confer type 2 ... -
Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort
(Journal article; Peer reviewed, 2022)Objective: The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until ... -
Early Gut Fungal and Bacterial Microbiota and Childhood Growth
(Journal article; Peer reviewed, 2020)Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut ... -
Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children
(Journal article; Peer reviewed, 2020)Background Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2–17 years old in Europe in 2012 and is administered as a nasal spray. Live-attenuated influenza vaccine induces both mucosal ... -
Early life environment and snoring in adulthood
(Peer reviewed; Journal article, 2008-08-22)Background: To our knowledge, no studies of the possible association of early life environment with snoring in adulthood have been published. We aimed to investigate whether early life environment is associated with snoring ... -
Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age
(Journal article; Peer reviewed, 2021)Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for ... -
Early manifestations of genetic risk for neurodevelopmental disorders
(Journal article; Peer reviewed, 2021)Background: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important ... -
Early outcome and restenosis after coronary stenting : intervention with stent-coatings, antioxidants and radiation
(Doctoral thesis, 2007-03-16) -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
(Journal article; Peer reviewed, 2022)Background: Immune checkpoint blockade (ICB) results in radiologic tumour response dynamics that differ from chemotherapy efficacy measures and require an early signal of clinical utility. Methods: Previously untreated, ... -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
(Journal article; Peer reviewed, 2023)Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a ... -
Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors
(Peer reviewed; Journal article, 2016)Background: Skin and soft tissue infections are common reasons for medical care. Use of broad-spectrum therapy and costs have increased. Assessment of early treatment response has been given a central role both in clinical ... -
Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study
(Journal article; Peer reviewed, 2022)Objective: To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. Setting: All neonatal intensive ... -
Early vascular aging in young and middle-aged ischemic stroke patients: The Norwegian stroke in the young study
(Peer reviewed; Journal article, 2014-11-18)Background: Ischemic stroke survivors have high risk of cardiovascular morbidity and mortality even at young age, suggesting that early arterial aging is common among such patients. Methods: We measured aortic stiffness ... -
Early-Onset Sepsis in Neonates - A Population-Based Study in South-West Norway From 1996 to 2018
(Journal article; Peer reviewed, 2021)Background: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy ... -
The effect of antibiotic stewardship interventions with stakeholder involvement in hospital settings: A multicentre, cluster randomized controlled intervention study
(Peer reviewed; Journal article, 2018-09-10)Background: There is limited evidence from multicenter, randomized controlled studies to inform planning and implementation of antibiotic stewardship interventions in hospitals. Methods: A cluster randomized, controlled, ... -
The Effect of Biological Treatment on Fatigue in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
(Journal article; Peer reviewed, 2023)Background: Fatigue is a frequent complaint in patients with inflammatory bowel disease. Biological drugs have demonstrated beneficial effects on some extraintestinal manifestations, but the effect on fatigue is not ... -
The effect of drug-eluting stents on target lesion revascularization in native coronary arteries: results from the NORSTENT randomized study
(Journal article; Peer reviewed, 2020)Background: The NORSTENT trial randomized 9,013 patients to percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) or bare-metal stent (BMS) with 5-year follow-up. No difference was found in the composite ... -
The effect of electroconvulsive therapy (ECT) on serum kynurenine pathway metabolites in late-life depression
(Journal article; Peer reviewed, 2023)Background: Depression is reportedly associated with alterations in kynurenine pathway metabolites (kynurenines). Several kynurenines are involved in glutamate signaling, and some have potentially neurotoxic effects while ...