Browsing Department of Clinical Science by Author "Aabakken, Lars"

Now showing items 1-5 of 5

    • Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease 

      Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Peer reviewed; Journal article, 2020)
      Background and Aim: Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut‐off concentration of adalimumab ...

    • Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2022)
      Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing knowledge ...

    • Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease 

      Grimstad, Tore; Kvivik, Ingeborg; Kvaløy, Jan Terje; Aabakken, Lars; Omdal, Roald (Peer reviewed; Journal article, 2020)
      Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ...

    • Histologic healing and factors associated with complete remission following conventional treatment in ulcerative colitis 

      Steinsbø, Øyvind; Carlsen, Arne; Aasprong, Ole Gunnar; Aabakken, Lars; Tvedt-Gundersen, Espen; Bjørkhaug, Steinar Traae; Gjerde, Rune; Karlsen, Lars Normann; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2022)
      Background: Endoscopic and histological activity scores in ulcerative colitis (UC) are associated with clinical outcomes and have become important targets of clinical trials. However, these endpoints have been scarcely ...

    • Less, but not gone—gluten-free diet effects on fatigue in celiac disease: a prospective controlled study 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2023)
      Introduction: Fatigue is a frequent complaint in patients with celiac disease. A gluten-free diet is the only established treatment for celiac disease, but how this diet influences fatigue is uncertain. We aimed to investigate ...