• Candidate markers for stratification and classification in rheumatoid arthritis 

      Bader, Lucius; Gullaksen, Stein-Erik; Blaser, Nello; Brun, Morten; Bringeland, Gerd Haga; Sulen, Andre; Gjesdal, Clara Gram; Vedeler, Christian A.; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-05)
      Rheumatoid arthritis (RA) is a chronic autoimmune, inflammatory disease, characterized by synovitis in small- and medium-sized joints and, if not treated early and efficiently, joint damage, and destruction. RA is a ...
    • Exploration of Cellular Signaling Patterns for the Stratification of Patients with Rheumatoid Arthritis 

      Bader, Lucius (Doctoral thesis, 2020-09-16)
      Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by synovial inflammation that, if not treated early and efficiently, causes joint damage. The proinflammatory cytokine tumor necrosis ...
    • Signaling effects of sodium hydrosulfide in healthy donor peripheral blood mononuclear cells 

      Sulen, Andre; Gullaksen, Stein-Erik; Bader, Lucius; McClymont, David; Skavland, Jørn; Gavasso, Sonia; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2016-11)
      Hydrogen sulfide (H2S) is an endogenous gasotransmitter in human physiology and inflammatory disease, however, with limited knowledge of how signal transduction pathways are involved in immune cells. To examine the effects ...
    • Titrating complex mass cytometry panels 

      Gullaksen, Stein-Erik; Bader, Lucius; Hellesøy, Monica; Sulen, Andre; Fagerholt, Oda Helen Eck; Engen, Caroline Benedicte Nitter; Skavland, Jørn; Gjertsen, Bjørn Tore; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-13)
      We describe here a simple and efficient antibody titration approach for cell‐surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well‐characterized backbone ...