• Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials 

      Pazan, Farhad; Petrovic, Mirko; Cherubini, Antonio; Onder, Graziano; Cruz-Jentoft, Alfonso J.; Denkinger, Michael D.; van der Cammen, Tischa J. M.; Stevenson, Jennifer M.; Ibrahim, Kinda; Rajkumar, Chakravarthi; Bakken, Marit Stordal; Baeyens, Jean-Pierre; Crome, Peter; Frühwald, Thomas; Gallaghar, Paul; Guðmundsson, Adalsteinn; Knol, Wilma; O’Mahony, Denis; Pilotto, Alberto; Rönnemaa, Elina; Serra-Rexach, José Antonio; Soulis, George; van Marum, Rob J.; Ziere, Gijsbertus; Mair, Alpana; Burkhardt, Heinrich; Neumann-Podczaska, Agnieszka; Wieczorowska-Tobis, Katarzyna; Fernandes, Marilia Andreia; Gruner, Heidi; Dallmeier, Dhayana; Beuscart, Jean-Baptiste; Van Der Velde, Nathalie; Wehling, Martin (Journal article; Peer reviewed, 2021)
      Background Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest ...