Browsing Department of Clinical Science by Author "Falk, Anna"
Now showing items 1-2 of 2
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Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD
Drakulic, Danijela; Djurovic, Srdjan; Syed, Yasir Ahmed; Trattaro, Sebastiano; Caporale, Nicolò; Falk, Anna; Ofir, Rivka; Heine, Vivi M.; Chawner, Samuel J.R.A.; Rodriguez-Moreno, Antonio; van den Bree, Marianne B.M.; Testa, Giuseppe; Petrakis, Spyros; Harwood, Adrian J. (Journal article; Peer reviewed, 2020)Patients diagnosed with chromosome microdeletions or duplications, known as copy number variants (CNVs), present a unique opportunity to investigate the relationship between patient genotype and cell phenotype. CNVs have ... -
Modeling psychiatric disorders: From genomic findings to cellular phenotypes
Falk, Anna; Heine, Vivi M.; Harwood, Adrian J.; Sullivan, Patrick F.; Peitz, Michael; Brüstle, Oliver; Shen, Sanbring; Sun, Yuh-Man; Glover, Joel; Posthuma, Daniëlle; Djurovic, Srdjan (Peer reviewed; Journal article, 2016)Major programs in psychiatric genetics have identified >150 risk loci for psychiatric disorders. These loci converge on a small number of functional pathways, which span conventional diagnostic criteria, suggesting a partly ...