Browsing Department of Clinical Science by Author "Falkowski, Katherine"
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Discovery of novel potential reversible peptidyl arginine deiminase inhibitor
Aliko, Ardita; Kaminska, Marta; Falkowski, Katherine; Bielecka, Ewa; Benedyk-Machaczka, Malgorzata; Malicki, Stanislaw; Koziel, Joanna; Wong, Alicia; Bryzek, Danuta; Kantyka, Tomasz Tadeusz; Mydel, Piotr Mateusz (Peer reviewed; Journal article, 2019)Citrullination, a posttranslational modification, is catalyzed by peptidylarginine deiminases (PADs), a unique family of enzymes that converts peptidyl-arginine to peptidyl-citrulline. Overexpression and/or increased PAD ...