• Epidemiology and health related quality of life in hypoparathyroidism in Norway 

      Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and ...
    • GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility 

      Eriksson, Daniel; Røyrvik, Ellen Christine; Aranda-Guillen, Maribel; Berger, Amund Holte; Landegren, Nils; Artaza, Haydee; Hallgren, Åsa; Grytaas, Marianne; Strøm, Sara; Bratland, Eirik; Botusan, Ileana; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Vaudel, Marc; Helgeland, Øyvind; Falorni, Alberto; Jørgensen, Anders Palmstrøm; Hulting, Anna-Lena; Svartberg, Johan; Ekwall, Olov; Fougner, Kristian J; Wahlberg, Jeanette; Nedrebø, Bjørn Gunnar; Dahlqvist, Per; Study group, Norwegian Addison Registry; Study Group, Swedish Addison Registry; Knappskog, Per Morten; Wolff, Anette Susanne Bøe; Bensing, Sophie; Johansson, Stefan; Kämpe, Olof; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)
      Autoimmune Addison’s disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first ...
    • Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6 

      Astor, Marianne; Løvås, Kristian; Wolff, Anette Susanne Bøe; Nedrebø, Bjørn Gunnar; Bratland, Eirik; Steen-Johnsen, Jon; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2015)
      Primary hypomagnesemia with secondary hypocalcemia (HSH) is an autosomal recessive disorder characterized by neuromuscular symptoms in infancy due to extremely low levels of serum magnesium and moderate to severe hypocalcemia. ...
    • Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy 

      Flølo, Tone Nygaard; Fosså, Alexander; Nedkvitne, Jonas Ingolf Petersson; Waage, Jo Erling Riise; Rekdal, Magne; Dankel, Simon N; Fernø, Johan; Mellgren, Gunnar; Nedrebø, Bjørn Gunnar (Journal article; Peer reviewed, 2023)
      We investigated whether adding gastropexy to sleeve gastrectomy (SG) reduced gastroesophageal reflux disease (GERD) in patients operated for severe obesity, assessed mainly by use of anti-reflux medication (ARM) and second ...
    • A longitudinal follow-up of autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2016-08)
      Context: Autoimmune polyendocrine syndrome type 1 (APS1) is a childhood-onset monogenic disease defined by the presence of two of the three major components: hypoparathyroidism, primary adrenocortical insufficiency, and ...
    • Markers of Subclinical Atherosclerosis in Severe Obesity and One Year after Bariatric Surgery 

      Kovac, Nina; Grymyr, Lisa Marie Dale; Gerdts, Eva; Nadirpour, Saied; Nedrebø, Bjørn Gunnar; Hjertaas, Johannes Just; Matre, Knut; Cramariuc, Dana (Journal article; Peer reviewed, 2022)
      Background: Aortic valve sclerosis (AVS), mitral valve sclerosis (MVS), remodeling of major arteries, and increased pericardial fat are associated with subclinical atherosclerosis. We assessed these markers of atherosclerosis ...
    • One-year impact of bariatric surgery on left ventricular mechanics: results from the prospective FatWest study 

      Grymyr, Lisa Marie Dale; Nadirpour, Saied; Gerdts, Eva; Nedrebø, Bjørn Gunnar; Hjertaas, Johannes Just; Matre, Knut; Cramariuc, Dana (Journal article; Peer reviewed, 2021)
      Aims Patients with severe obesity are predisposed to left ventricular (LV) hypertrophy, increased myocardial oxygen demand, and impaired myocardial mechanics. Bariatric surgery leads to rapid weight loss and improves ...
    • Plasma-Metanephrines in Patients with Autoimmune Addison’s Disease with and without Residual Adrenocortical Function 

      Åkerman, Anna-Karin; Sævik, Åse Bjorvatn; Thorsby, Per Medbøe; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Höybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Øksnes, Marianne; Bensing, Sophie (Journal article; Peer reviewed, 2023-05-22)
      Purpose: Residual adrenocortical function, RAF, has recently been demonstrated in one-third of patients with autoimmune Addison’s disease (AAD). Here, we set out to explore any influence of RAF on the levels of plasma ...
    • Residual Corticosteroid Production in Autoimmune Addison Disease 

      Sævik, Åse Bjorvatn; Åkerman, Anna-Karin; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Høybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Valland, Susanna Fonneland; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Bensing, Sophie; Øksnes, Marianne (Journal article; Peer reviewed, 2020)
      Design: Two-staged, cross-sectional clinical study in 17 centers (Norway, Sweden, and Germany). Residual glucocorticoid (GC) production was defined as quantifiable serum cortisol and 11-deoxycortisol and residual ...
    • Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance 

      Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, André; Skartveit, Linn; Fjære, Even; McCann, Adrian; Dyer, Laurence; Willems, Aron; Bjune, Jan-Inge; Bjune, Mona Synnøve; Våge, Villy; Nielsen, Hans Jørgen; Thorsen, Håvard Luong; Nedrebø, Bjørn Gunnar; Busch, Christian; Steen, Vidar M.; Blüher, Matthias; Jacobson, Peter; Svensson, Per-Arne; Fernø, Johan; Rydén, Mikael; Arner, Peter; Nygård, Ottar; Claussnitzer, Melina; Ellingsen, Ståle; Madsen, Lise; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2021)
      Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose ...
    • Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy 

      Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)
      Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ...